Reactome | GPR35 [plasma membrane]

GPR35 [plasma membrane]

Stable Identifier

R-HSA-3295332

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

G-protein coupled receptor 35, GPR35_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HC97 GPR35

Gene Names

GPR35

Chain

chain:1-309

Reference Genes

BioGPS Gene:2859 GPR35

COSMIC (genes):GPR35 GPR35

CTD Gene:2859 GPR35

dbSNP Gene:2859 GPR35

ENSEMBL:ENSG00000178623 GPR35

HGNC:4492 GPR35

KEGG:hsa:2859 GPR35

Monarch:2859 GPR35

NCBI Gene:2859 GPR35

OMIM:602646 GPR35

UCSC:Q9HC97 GPR35

Reference Transcript

Other Identifiers

11729307_x_at

11738894_a_at

11752441_s_at

11756998_s_at

16893246

210264_3p_at

210264_PM_at

210264_at

2535904

2535905

2535909

2535910

2535911

2535915

2535918

2535919

2535928

2535929

2535930

2535931

2535932

2535934

2535935

2535936

2535938

2535940

2859

31700_at

8049722

84195_at

A_14_P139695

A_23_P154245

A_23_P305550

A_33_P3375368

GE62650

GE87092

GO:0004930

GO:0004950

GO:0005886

GO:0007010

GO:0007186

GO:0007200

GO:0007204

GO:0016020

GO:0016494

GO:0035025

GO:0060089

GO:0070098

GO:1901386

GO:1904456

HMNXSV003028091

HMNXSV003050264

ILMN_1677357

ILMN_1710221

PH_hs_0012912

TC02005016.hg

g10503932_3p_at

g10503932_3p_x_at

Participates

as a component of

GPR35:Kynurenic acid [plasma membrane] (Homo sapiens)

as an input of

GPR35 binds kynurenic acid (Homo sapiens)

Inferred To

Gpr35 [plasma membrane] (Mus musculus)

Gpr35 [plasma membrane] (Rattus norvegicus)

LOC100490589 [plasma membrane] (Xenopus tropicalis)

Homologues of GPR35 [plasma membrane] (Gallus gallus)

gpr35.1 [plasma membrane] (Danio rerio)

gnrr-4 [plasma membrane] (Caenorhabditis elegans)

GPR35 [plasma membrane] (Bos taurus)

GPR35 [plasma membrane] (Canis familiaris)

GPR35 [plasma membrane] (Gallus gallus)

GPR35 [plasma membrane] (Sus scrofa)

Cross References

ZINC - World Drugs

GPR35_HUMAN

Guide to Pharmacology - Targets

102

OpenTargets

ENSG00000178623

ENSEMBL

ENST00000407714, ENST00000438013, ENSP00000322731, ENST00000430267, ENSP00000415890, ENST00000319838, ENSP00000385140, ENSP00000384263, ENSP00000411788, ENST00000403859

ZINC - FDA approved

GPR35_HUMAN

ZINC - Substances

GPR35_HUMAN

ZINC - Biogenic

GPR35_HUMAN

ZINC target

Q9HC97

PRO

Q9HC97

GlyGen

Q9HC97

PDB

8H8J

ZINC - Investigational

GPR35_HUMAN

ZINC - Metabolites

GPR35_HUMAN

HPA

ENSG00000178623-GPR35

Pharos - Targets

Q9HC97

Orphanet

GPR35

ZINC - Predictions - Purchasable

GPR35_HUMAN

HMDB Protein

HMDBP13667

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15800 MSMO1	1	MSMO1 [endoplasmic reticulum membrane] (R-HSA-194648)	0.547	2
UniProt:O95197 RTN3	1	RTN3 [plasma membrane] (R-HSA-8849907)	0.547	2
UniProt:O43760 SNG2			0.547	2
UniProt:Q9NX61 T161A			0.547	2
UniProt:Q9Y679 AUP1			0.547	2
UniProt:Q5BJH7 YIF1B			0.547	2
UniProt:Q6S8J3 POTEE	1	POTEE [cytosol] (R-HSA-9715126)	0.527	2
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.527	2
UniProt:Q96EK9 KTI12			0.527	2
UniProt:Q9UII2 ATIF1			0.527	2
UniProt:P17931 LGALS3	3	LGALS3 [ficolin-1-rich granule membrane] (R-HSA-6803307) LGALS3 [plasma membrane] (R-HSA-879445) LGALS3 [secretory granule membrane] (R-HSA-6803327)	0.527	2

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