Reactome | ATP5MG [mitochondrial inner membrane]

ATP5MG [mitochondrial inner membrane]

Stable Identifier

R-HSA-50518

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATPase subunit g, ATP5L, ATP synthase g chain, mitochondrial

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MG [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5MG [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75964 ATP5MG

Gene Names

ATP5MG, ATP5L

Chain

initiator methionine:, chain:2-103

Reference Genes

BioGPS Gene:10632 ATP5MG

COSMIC (genes):ATP5MG ATP5MG

CTD Gene:10632 ATP5MG

dbSNP Gene:10632 ATP5MG

ENSEMBL:ENSG00000167283 ATP5L

HGNC:14247 ATP5MG

KEGG:hsa:10632 ATP5MG

Monarch:10632 ATP5MG

NCBI Gene:10632 ATP5MG

OMIM:617473 ATP5MG

UCSC:O75964 ATP5MG

Reference Transcript

RefSeq:NM_006476.4 ATP5MG

Other Identifiers

10632

11721238_s_at

11721239_x_at

11757636_x_at

16731846

207573_PM_x_at

207573_x_at

208745_PM_at

208745_at

208746_PM_x_at

208746_x_at

210453_PM_x_at

210453_x_at

3351360

3351361

3351364

3351365

3351366

3351367

3351368

3351369

3351370

3351371

3351372

3351373

3351374

3351375

3351377

3351378

3351382

3351384

3351386

38693_at

7944216

A_14_P115231

A_14_P139887

A_23_P75622

A_24_P96527

GE56285

GE703397

GE85997

GE86529

GO:0000276

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0006754

GO:0015078

GO:0015986

GO:0016020

GO:0016874

GO:0042776

GO:0043226

GO:0045259

GO:0045263

GO:0046933

GO:0055085

GO:0055086

GO:1901135

GO:1902600

HMNXSV003019965

Hs.107476.1.S2_3p_at

ILMN_1812638

ILMN_2079285

PH_hs_0005969

TC11001063.hg

TC11002898.hg

g4454685_3p_x_at

g5453560_3p_a_at

p28284

p2962

Participates

as a member of

Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as a component of

ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ATP20 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

ATP5MG [mitochondrial inner membrane] (Bos taurus)

ATP5MG [mitochondrial inner membrane] (Canis familiaris)

ATP5MG [mitochondrial inner membrane] (Sus scrofa)

Atp5mg [mitochondrial inner membrane] (Mus musculus)

Atp5mg [mitochondrial inner membrane] (Rattus norvegicus)

asg-2 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATPsynG [mitochondrial inner membrane] (Drosophila melanogaster)

ATP5L [mitochondrial inner membrane] (Gallus gallus)

atp5l [mitochondrial inner membrane] (Danio rerio)

Cross References

ENSEMBL

ENSP00000300688, ENST00000300688

OpenTargets

ENSG00000167283

HPA

ENSG00000167283-ATP5MG

PRO

O75964

Pharos - Targets

O75964

PDB

8H9J, 8KHF, 8H9S, 8H9Q, 8H9T, 8H9M, 8H9U, 8H9F, 8H9V, 8KI3

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	7