Reactome | VPU (P05919) [plasma membrane]

VPU (P05919) [plasma membrane]

Stable Identifier

R-HIV-3149423

Type

Protein [EntityWithAccessionedSequence]

Species

Human immunodeficiency virus 1

Compartment

plasma membrane

GO Cellular Component

host cell endoplasmic reticulum membrane (0044167)

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External Reference Information

External Reference

UniProt:P05919 vpu

Gene Names

vpu

Chain

chain:1-81

Participates

as an input of

Packaging of HIV virion on the host cell plasma membrane (Homo sapiens)

as an output of

Transport of VPU to Plasma Membrane (Homo sapiens)

Other forms of this molecule

VPU (P05919) protein [extracellular region]

VPU (P05919) protein [cytosol]

VPU (P05919) protein [nucleoplasm]

VPU (P05919) [endoplasmic reticulum membrane]

VPU (P05919) [Golgi membrane]

Cross References

PDB

2N29

Interactors (43)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y297 BTRC	2	BTRC [cytosol] (R-HSA-174237) BTRC [nucleoplasm] (R-HSA-3361753)	0.597	3
UniProt:Q13616 CUL1	3	G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519) CUL1 [nucleoplasm] (R-HSA-187551) CUL1 [cytosol] (R-HSA-174230)	0.597	4
UniProt:P01730 CD4	4	CD4 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869082) CD4 [early endosome] (R-HSA-182147) CD4 [endoplasmic reticulum membrane] (R-HSA-180575) CD4 [plasma membrane] (R-HSA-167542)	0.524	3
UniProt:Q9NQC3 RTN4	1	RTN4 [plasma membrane] (R-HSA-194556)	0.462	4
UniProt:Q9GZT3 SLIRP			0.462	4
UniProt:P42695 NCAPD3	3	p-T1415,S1419-NCAPD3 [nucleoplasm] (R-HSA-2294594) p-T1415-NCAPD3 [nucleoplasm] (R-HSA-2294587) NCAPD3 [nucleoplasm] (R-HSA-1629790)	0.462	2
UniProt:Q99653 CHP1	1	p-CHP1 [plasma membrane] (R-HSA-5333747)	0.462	2
UniProt:Q63HN8 RNF213	3	RNF213(1-1172)-p-7Y ALK(1058-1620) fusion [cytosol] (R-HSA-9715284) RNF213(1-1172)-ALK(1058-1620) fusion [cytosol] (R-HSA-9715291) RNF213 [cytosol] (R-HSA-9635613)	0.462	2
UniProt:Q15185 PTGES3	2	PTGES3 [nucleoplasm] (R-HSA-5082403) PTGES3 [cytosol] (R-HSA-265269)	0.462	2
UniProt:Q8TC07 TBC1D15	1	TBC1D15 [cytosol] (R-HSA-8854150)	0.462	2
UniProt:P20020 ATP2B1	1	ATP2B1 [plasma membrane] (R-HSA-418301)	0.462	2
UniProt:P26038 MSN	4	p-T558-MSN [cytosol] (R-HSA-9663005) MSN(2-448)-p-7Y ALK(1064-1620) fusion [cytosol] (R-HSA-9711971) MSN(2-448)-ALK(1064-1620) fusion [cytosol] (R-HSA-9711966) MSN [cytosol] (R-HSA-437350)	0.462	2
UniProt:P78527 PRKDC	4	K48polyUb-PRKDC [cytosol] (R-HSA-8938766) PRKDC [cytosol] (R-HSA-3134816) PRKDC [nucleoplasm] (R-HSA-62161) p-T2609,S2612,T2638,T2647-PRKDC [nucleoplasm] (R-HSA-76302)	0.462	2
UniProt:O14980 XPO1	2	XPO1 [nucleoplasm] (R-HSA-165529) XPO1 [cytosol] (R-HSA-165539)	0.462	2
UniProt:P63208 SKP1	2	SKP1 [nucleoplasm] (R-HSA-187538) SKP1 [cytosol] (R-HSA-174150)	0.462	4
UniProt:O95197 RTN3	1	RTN3 [plasma membrane] (R-HSA-8849907)	0.462	4
UniProt:Q86T03 PIP4P1	2	TMEM55B [nucleoplasm] (R-HSA-6810405) TMEM55B [late endosome membrane] (R-HSA-6810395)	0.462	4
UniProt:P13598 ICAM2	1	ICAM2 [plasma membrane] (R-HSA-197852)	0.462	2
UniProt:P06576 ATP5F1B	6	ATP5B [mitochondrial inner membrane] (R-HSA-1299441) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B [mitochondrial matrix] (R-HSA-164576)	0.462	2
UniProt:P42704 LRPPRC	1	LRPPRC [mitochondrial matrix] (R-HSA-5336174)	0.462	4
UniProt:O14828 SCAM3			0.462	4
UniProt:Q9UHQ9 CYB5R1	3	CYB5R1 [plasma membrane] (R-HSA-8848888) CYB5R1 [platelet alpha granule membrane] (R-HSA-8848891) CYB5R1 [endoplasmic reticulum membrane] (R-HSA-6806847)	0.462	4
UniProt:P78357 CNTNAP1	1	CNTNAP1 [plasma membrane] (R-HSA-373626)	0.462	2
UniProt:Q16537 PPP2R5E	1	PPP2R5E [cytosol] (R-HSA-1638770)	0.462	2
UniProt:Q9NVI7 ATD3A			0.462	4
UniProt:P24539 ATP5PB	1	ATP5F1 [mitochondrial inner membrane] (R-HSA-164537)	0.462	2
UniProt:Q9HAV4 XPO5	2	XPO5 [cytosol] (R-HSA-847719) XPO5 [nucleoplasm] (R-HSA-847721)	0.462	2
UniProt:Q96P70 IPO9			0.462	4
UniProt:Q96F15 GIMA5			0.462	2
UniProt:P48047 ATP5PO	1	ATP5O [mitochondrial inner membrane] (R-HSA-164533)	0.462	2
UniProt:Q86XR8 CEP57	1	CEP57 [cytosol] (R-HSA-380271)	0.462	2
UniProt:P30049 ATP5F1D	1	ATP5D [mitochondrial matrix] (R-HSA-164574)	0.462	2
UniProt:O95573 ACSL3	2	ACSL3 [endoplasmic reticulum membrane] (R-HSA-548787) ACSL3 [mitochondrial outer membrane] (R-HSA-9632656)	0.462	2
UniProt:Q53GQ0 HSD17B12	1	HSD17B12 [endoplasmic reticulum membrane] (R-HSA-548766)	0.462	2
UniProt:Q969Z0 FAKD4			0.462	2
UniProt:Q9Y6D6 BIG1			0.462	2
UniProt:Q9Y6D5 ARFGEF2	1	ARFGEF2 [cytosol] (R-HSA-391301)	0.462	2
UniProt:P55084 HADHB	1	HADHB [mitochondrial inner membrane] (R-HSA-77266)	0.462	4
UniProt:P18859 ATP5PF	1	ATP5J [mitochondrial inner membrane] (R-HSA-164532)	0.462	4
UniProt:Q5T9A4 ATAD3B	3	ATAD3B [ficolin-1-rich granule membrane] (R-HSA-6801277) ATAD3B [plasma membrane] (R-HSA-6806518) ATAD3B [secretory granule membrane] (R-HSA-6801313)	0.462	4
UniProt:P40939 HADHA	1	HADHA [mitochondrial inner membrane] (R-HSA-77264)	0.462	4
UniProt:Q9UBB4 ATX10			0.462	4
UniProt:Q9UKB1 FBXW11	1	FBXW11 [cytosol] (R-HSA-976035)	0.462	4

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