Reactome | ATP5A1(1-553) [cytosol]

ATP5A1(1-553) [cytosol]

Stable Identifier

R-HSA-1267955

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ATP5A1 precursor, ATP synthase alpha chain precursor

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P25705 ATP5F1A

Gene Names

ATP5F1A, ATP5A, ATP5A1, ATP5AL2, ATPM

Chain

transit peptide:1-43, chain:44-553

Reference Genes

BioGPS Gene:498 ATP5F1A

COSMIC (genes):ATP5F1A ATP5F1A

CTD Gene:498 ATP5F1A

dbSNP Gene:498 ATP5F1A

ENSEMBL:ENSG00000152234 ATP5A1

ENSEMBL_homo_sapiens_GENE:ENSG00000152234.16 ATP5F1A

HGNC:823 ATP5F1A

KEGG Gene (Homo sapiens):498 ATP5F1A

Monarch:498 ATP5F1A

NCBI Gene:498 ATP5F1A

OMIM:164360 ATP5F1A

UCSC:P25705 ATP5F1A

Reference Transcript

Other Identifiers

11728637_a_at

11753328_a_at

11753329_x_at

11756890_s_at

16734670

16854926

16854928

16909411

213738_PM_s_at

213738_s_at

2603023

3206246

3206249

3206267

3206269

3206653

3697993

3698012

3806248

3806250

3806252

3806254

3806255

3806256

3806258

3806259

3806261

3806263

3806265

3806266

3806267

3806271

3806273

3806274

3806275

3806279

3806282

3806283

3806284

3806285

3806286

3806288

40096_at

498

67371_at

7945892

8023061

8023063

8059648

A_19_P00802407

A_24_P245358

D14710_at

GE57089

GE584414

GE792903

GO:0000166

GO:0000275

GO:0001937

GO:0002020

GO:0003723

GO:0003824

GO:0005215

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005739

GO:0005743

GO:0005753

GO:0005754

GO:0005759

GO:0005886

GO:0006091

GO:0006629

GO:0006754

GO:0006811

GO:0008180

GO:0009986

GO:0014850

GO:0015986

GO:0016020

GO:0016469

GO:0016787

GO:0016874

GO:0016887

GO:0032559

GO:0042288

GO:0042776

GO:0043226

GO:0043531

GO:0043532

GO:0043536

GO:0045121

GO:0045259

GO:0045261

GO:0045471

GO:0046034

GO:0046933

GO:0048870

GO:0055085

GO:0055086

GO:0070062

GO:0071549

GO:0071732

GO:0140657

GO:1901135

GO:1902600

HMNXSV003042184

Hs.155101.3.A1_3p_a_at

ILMN_1764494

ILMN_1874613

ILMN_2341363

TC18000479.hg

TC18000480.hg

Participates

as a candidate of

Cargo of TOMM40 [cytosol] (Homo sapiens)

Other forms of this molecule

ATP5A1(1-553) [mitochondrial intermembrane space]

ATP5F1A [mitochondrial matrix]

Cross References

RefSeq

NP_004037.1, NP_001244263.1, NP_001244264.1, NP_001001935.1, NP_001001937.1

Guide to Pharmacology - Targets

796

OpenTargets

ENSG00000152234

HPA

ENSG00000152234-ATP5F1A

GeneCards

P25705

Ensembl

ENST00000398752, ENSP00000467037, ENSG00000152234, ENSP00000465477, ENSP00000282050, ENST00000590665, ENST00000282050, ENST00000593152, ENSP00000381736

PRO

P25705

Pharos - Targets

P25705

Orphanet

22151

HMDB Protein

HMDBP01448

PDB

8H9P, 8H9I, 8H9E, 8H9S, 8H9U, 8H9L, 8H9V, 8H9T

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.744	7
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.688	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	20
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q9NTG7 SIRT3	2	SIRT3 [nucleoplasm] (R-HSA-9622879) SIRT3(?-399) [mitochondrial matrix] (R-HSA-1605416)	0.524	2

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