Reactome | MT-ATP8 [mitochondrial inner membrane]

MT-ATP8 [mitochondrial inner membrane]

Stable Identifier

R-HSA-50500

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase protein 8 , ATPase subunit 8, A6L

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Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        MT-ATP8 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        MT-ATP8 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P03928 MT-ATP8

Gene Names

MT-ATP8, ATP8, ATPASE8, MTATP8

Chain

chain:1-68

Reference Genes

BioGPS Gene:4509 MT-ATP8

COSMIC (genes):MT-ATP8 MT-ATP8

CTD Gene:4509 MT-ATP8

dbSNP Gene:4509 MT-ATP8

ENSEMBL:ENSG00000228253 MT-ATP8

HGNC:7415 MT-ATP8

KEGG:hsa:4509 MT-ATP8

Monarch:4509 MT-ATP8

NCBI Gene:4509 MT-ATP8

OMIM:516070 MT-ATP8

UCSC:P03928 MT-ATP8

Reference Transcript

RefSeq:NC_012920.1 MT-CYB

Other Identifiers

11758423_s_at

1553567_3p_s_at

1553567_PM_s_at

1553567_s_at

17100663

17100665

17126266

17126268

2315317

2315318

2315319

2492706

2492708

4037635

4037637

4037639

4037640

4037641

4037642

4037643

4037644

4037645

4037646

4037647

4509

7896752

8043375

8165665

8165667

8165669

A_23_P337726

A_33_P3410700

GO:0000276

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0006754

GO:0015078

GO:0015986

GO:0016020

GO:0016874

GO:0031966

GO:0042776

GO:0043226

GO:0045259

GO:0045263

GO:0046933

GO:0055085

GO:0055086

GO:1901135

GO:1902600

HMNXSV003022003

HMNXSV003041642

Hs2Affx.1.41.S1_3p_s_at

Hs2Affx.1.43.S1_3p_x_at

PH_hs_0033947

PH_hs_0036541

RNA143496|tRNA_413_70

TC01000013.hg

TC0M000005.hg

TC0M000022.hg

Participates

as a component of

ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)

Inferred To

Mt-atp8 [mitochondrial inner membrane] (Rattus norvegicus)

Mtatp8 [mitochondrial inner membrane] (Mus musculus)

MT-ATP8 [mitochondrial inner membrane] (Bos taurus)

MT-ATP8 [mitochondrial inner membrane] (Sus scrofa)

Ghost homologue of MT-ATP8 [mitochondrial inner membrane] (Caenorhabditis elegans)

Ghost homologue of MT-ATP8 [mitochondrial inner membrane] (Canis familiaris)

Ghost homologue of MT-ATP8 [mitochondrial inner membrane] (Danio rerio)

Ghost homologue of MT-ATP8 [mitochondrial inner membrane] (Drosophila melanogaster)

Ghost homologue of MT-ATP8 [mitochondrial inner membrane] (Gallus gallus)

Cross References

Guide to Pharmacology - Targets

809

ENSEMBL

ENSP00000355265, ENSG00000228253, ENST00000361851

OpenTargets

ENSG00000228253

GeneCards

MT-ATP8

HPA

ENSG00000228253-MT-ATP8

PRO

P03928

Pharos - Targets

P03928

Orphanet

MT-ATP8

HMDB Protein

HMDBP01315

PDB

8H9T, 8H9F, 8KI3, 8H9M, 8H9Q, 8H9V, 8H9J, 8H9S, 8KHF, 8H9U

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25090 FPR2	4	FPR2 [plasma membrane] (R-HSA-416408) FPR2 [tertiary granule membrane] (R-HSA-6803296) FPR2 [specific granule membrane] (R-HSA-6803319) FPR2 [ficolin-1-rich granule membrane] (R-HSA-6803335)	0.527	2