Reactome | UniProt:P54253 ATX1

UniProt:P54253 ATX1

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

ATXN1, Q17S02, Q9UJG2, Q9Y4J1, ATX1, SCA1, Spinocerebellar ataxia type 1 protein, ENSP00000244769.3, ENSP00000416360.1

List of interactors in Reactome

Interactors (79)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P62258	1	YWHAE [cytosol] (R-HSA-194368)	0.919	15
P63104	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.882	13
Q12933	1	TRAF2 [cytosol] (R-HSA-66370)	0.859	14
Q6NXG1	1	ESRP1 [nucleoplasm] (R-HSA-6803472)	0.805	12
P46108	1	CRK [cytosol] (R-HSA-2980677)	0.77	9
P31946	1	YWHAB [cytosol] (R-HSA-48888)	0.737	5
Q14012	1	CAMK1 [cytosol] (R-HSA-9619207)	0.718	12
Q92993	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.709	9
P23528	2	CFL1 [cytosol] (R-HSA-350751) p-S3-CFL1 [cytosol] (R-HSA-399813)	0.703	11
P63208	1	SKP1 [cytosol] (R-HSA-174150)	0.696	6
Q9BZK7	1	TBL1XR1 [nucleoplasm] (R-HSA-351643)	0.696	6
P26368	2	5OHK15,276-U2AF2 [nucleoplasm] (R-HSA-9630011) U2AF2 [nucleoplasm] (R-HSA-71987)	0.674	5
O43684	1	BUB3 [cytosol] (R-HSA-141416)	0.666	7
O43776	1	NARS [cytosol] (R-HSA-379625)	0.666	4
O75925	1	PIAS1 [nucleoplasm] (R-HSA-877307)	0.666	7
P06241	3	FYN [cytosol] (R-HSA-200917) p-Y420-FYN [cytosol] (R-HSA-391821) p-Y531-FYN [cytosol] (R-HSA-391819)	0.666	8
P11142	5	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.666	13
P14324	1	FDPS [cytosol] (R-HSA-981566)	0.666	4
P17980	1	PSMC3 [cytosol] (R-HSA-68774)	0.666	7
P25789	1	PSMA4 [cytosol] (R-HSA-68730)	0.666	7
P36956	1	SREBF1(1-1147) [endoplasmic reticulum membrane] (R-HSA-1368141)	0.666	5
P41222	1	PTGDS [endoplasmic reticulum membrane] (R-HSA-2142814)	0.666	5
P61421	2	ATP6V0D1 [endosome membrane] (R-HSA-912592) ATP6V0D1 [lysosomal membrane] (R-HSA-9640177)	0.666	7
P63279	3	monoSUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [cytosol] (R-HSA-4655342) UBE2I [nucleoplasm] (R-HSA-912481)	0.666	7
Q13501	2	K7 ub-SQSTM1 [cytosol] (R-HSA-9759088) SQSTM1 [cytosol] (R-HSA-193937)	0.666	4
Q15717	3	ELAVL1 [nucleoplasm] (R-HSA-450601) p-S158,S221-ELAVL1 [nucleoplasm] (R-HSA-450576) p-S221,S318-ELAVL1 [nucleoplasm] (R-HSA-450532)	0.666	7
Q6DKK2	1	TTC19 [mitochondrial inner membrane] (R-HSA-9906047)	0.666	7
Q969X2	1	ST6GALNAC6 [Golgi membrane] (R-HSA-981855)	0.666	7
Q9H0E2	1	TOLLIP [cytosol] (R-HSA-446885)	0.666	7
Q9UBE8	1	NLK [cytosol] (R-HSA-4411330)	0.666	4
Q13887	1	KLF5 [nucleoplasm] (R-HSA-381279)	0.659	7
Q06330	1	RBPJ [nucleoplasm] (R-HSA-3008668)	0.641	7
O00560	1	SDCBP [cytosol] (R-HSA-373639)	0.556	6
O14503	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.556	3
O43909	1	EXTL3 [endoplasmic reticulum membrane] (R-HSA-535476)	0.556	3
O60828	1	PQBP1 [nucleoplasm] (R-HSA-8867889)	0.556	3
O95630	1	STAMBP [cytosol] (R-HSA-5693063)	0.556	6
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.556	8
P06576	1	ATP5F1B [mitochondrial matrix] (R-HSA-164576)	0.556	3
P09017	1	HOXC4 [nucleoplasm] (R-HSA-5617871)	0.556	6
P0DMV8	2	HSPA1A [cytosol] (R-HSA-6792602) HSPA1A [nucleoplasm] (R-HSA-6792605)	0.556	3
P14678	1	SNRPB [cytosol] (R-HSA-191798)	0.556	3
P17612	2	PRKACA [cytosol] (R-HSA-57844) PRKACA [mitochondrial matrix] (R-HSA-9838291)	0.556	3
P18847	1	ATF3 [nucleoplasm] (R-HSA-535543)	0.556	6
P22681	3	CBL [cytosol] (R-HSA-112199) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826)	0.556	3
P25786	1	PSMA1 [cytosol] (R-HSA-68724)	0.556	3
P28070	2	pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.556	6
P31749	8	AKT1 [cytosol] (R-HSA-58252) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 [cytosol] (R-HSA-9841264) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.556	6
P37173	2	NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 [plasma membrane] (R-HSA-170842)	0.556	3
P39687	1	ANP32A [nucleoplasm] (R-HSA-450467)	0.556	3
P42336	1	PIK3CA [cytosol] (R-HSA-74787)	0.556	3
P46782	1	RPS5 [nucleoplasm] (R-HSA-6791188)	0.556	3
P50454	1	SERPINH1 [endoplasmic reticulum lumen] (R-HSA-2127480)	0.556	3
P54819	1	AK2 [mitochondrial intermembrane space] (R-HSA-57822)	0.556	3
P55072	2	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [cytosol] (R-HSA-1181251)	0.556	3
P55854	2	SUMO3 [nucleoplasm] (R-HSA-2984269) SUMO3(1-103) [nucleoplasm] (R-HSA-2990830)	0.556	6
P62316	1	SNRPD2 [cytosol] (R-HSA-191810)	0.556	3
P62318	1	2xMe-SNRPD3 [cytosol] (R-HSA-191781)	0.556	3
Q06547	1	NRF2 beta-2 subunit [nucleoplasm] (R-HSA-1592200)	0.556	6
Q08117	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
Q09028	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.556	3
Q14457	1	BECN1 [cytosol] (R-HSA-1632841)	0.556	6
Q15738	1	NSDHL [endoplasmic reticulum membrane] (R-HSA-194707)	0.556	3
Q6VY07	1	PACS1 [cytosol] (R-HSA-167634)	0.556	6
Q70CQ3	1	USP30 [peroxisomal membrane] (R-HSA-9674135)	0.556	3
Q96HC4	1	PDLIM5 [cytosol] (R-HSA-6794246)	0.556	6
Q96NC0	1	ZMAT2 [nucleoplasm] (R-HSA-9770248)	0.556	6
Q9BUB5	1	p-T250,T255,T385,S437-MKNK1 [cytosol] (R-HSA-947860)	0.556	6
Q9BYZ2	1	LDHAL6B [mitochondrial matrix] (R-HSA-6807613)	0.556	6
Q9H0Y0	1	ATG10 [cytosol] (R-HSA-5671733)	0.556	6
Q9H553	1	ALG2 [endoplasmic reticulum membrane] (R-HSA-449336)	0.556	3
Q9P1U0	1	ZNRD1 [nucleoplasm] (R-HSA-5419292)	0.556	3
P32243	1	OTX2 [nucleoplasm] (R-HSA-9832936)	0.553	2
Q15637	1	SF1 [nucleoplasm] (R-HSA-8865928)	0.547	2
O75909	1	CCNK [nucleoplasm] (R-HSA-6796619)	0.508	2
P53990	1	IST1 [cytosol] (R-HSA-9668516)	0.508	2
Q9NWB1	1	RBFOX1 [nucleoplasm] (R-HSA-400307)	0.508	2
Q96HA1	1	POM121 [nuclear envelope] (R-HSA-157747)	0.488	2
P37840	3	p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.462	3