Reactome | B4GALT3 [Golgi membrane]

B4GALT3 [Golgi membrane]

Stable Identifier

R-HSA-975922

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Beta-1,4-galactosyltransferase 3, B4GT3_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
        
        N-Glycan antennae elongation (Homo sapiens)
        
        Addition of galactose by beta 4-galactosyltransferases (Homo sapiens)
        
        B4GALT1-6 homodimers [Golgi membrane] (Homo sapiens)
        
        B4GALT3 homodimer [Golgi membrane] (Homo sapiens)
        
        B4GALT3 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O60512 B4GALT3

Gene Names

B4GALT3

Chain

chain:1-393

Reference Genes

BioGPS Gene:8703 B4GALT3

COSMIC (genes):B4GALT3 B4GALT3

CTD Gene:8703 B4GALT3

dbSNP Gene:8703 B4GALT3

ENSEMBL:ENSG00000158850 B4GALT3

HGNC:926 B4GALT3

KEGG:hsa:8703 B4GALT3

Monarch:8703 B4GALT3

NCBI Gene:8703 B4GALT3

OMIM:604014 B4GALT3

UCSC:O60512 B4GALT3

Reference Transcript

Other Identifiers

11716856_a_at

16695602

210243_PM_s_at

210243_s_at

238312_PM_s_at

238312_s_at

2440665

2440666

2440667

2440669

2440670

2440671

2440672

2440673

2440674

2440675

2440676

2440677

2440678

2440679

2440680

2440681

2440682

2440683

2440684

2440685

2440686

2440687

2440688

2440689

2440690

2440691

2440692

2440693

2440694

2440695

2440696

2440697

39445_at

7921806

83744_at

8703

A_23_P103919

A_33_P3335999

GE54326

GO:0000139

GO:0003831

GO:0003945

GO:0005794

GO:0005829

GO:0005975

GO:0006486

GO:0006629

GO:0006682

GO:0008378

GO:0016020

GO:0016740

GO:0016757

GO:0032580

GO:0046872

GO:0070062

GO:0070085

GO:1901135

HMNXSV003019217

Hs.157267.1.A1_3p_at

ILMN_1692267

PH_hs_0016047

TC01003420.hg

g3132897_3p_s_at

Participates

as a component of

B4GALT3 homodimer [Golgi membrane] (Homo sapiens)

Inferred To

b4galt3 [Golgi membrane] (Xenopus tropicalis)

B4GALT3 [Golgi membrane] (Bos taurus)

B4GALT3 [Golgi membrane] (Canis familiaris)

B4GALT3 [Golgi membrane] (Gallus gallus)

B4GALT3 [Golgi membrane] (Sus scrofa)

B4galt3 [Golgi membrane] (Mus musculus)

B4galt3 [Golgi membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_054195372.1, XP_054195374.1, NP_001186803.1, NP_001186802.1, XP_047289355.1, NP_003770.1, XP_054195375.1, XP_054195373.1, XP_024306308.1, XP_024306309.1, XP_005245623.1

OpenTargets

ENSG00000158850

ENSEMBL

ENSG00000158850, ENST00000367998, ENST00000622395, ENST00000319769, ENSP00000480428, ENSP00000320965, ENSP00000356977

IntEnz

2.4.1.38, 2.4.1.90, 2.4.1.275

HPA

ENSG00000158850-B4GALT3

GeneCards

B4GALT3

PRO

O60512

Pharos - Targets

O60512

GlyGen

O60512

HMDB Protein

HMDBP01032

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:P06576 ATP5F1B	6	ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B [mitochondrial inner membrane] (R-HSA-1299441) ATP5F1B [mitochondrial matrix] (R-HSA-164576)	0.527	4
UniProt:Q9H5K3 POMK	1	POMK [endoplasmic reticulum membrane] (R-HSA-8879120)	0.527	2
UniProt:P27824 CANX	3	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum membrane] (R-HSA-9932989)	0.527	2