Reactome | B4GALT3 [Golgi membrane]

B4GALT3 [Golgi membrane]

Stable Identifier

R-HSA-975922

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Beta-1,4-galactosyltransferase 3, B4GT3_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - N-glycan antennae elongation in the medial/trans-Golgi (Homo sapiens)
        
        N-Glycan antennae elongation (Homo sapiens)
        
        Addition of galactose by beta 4-galactosyltransferases (Homo sapiens)
        
        B4GALT1-6 homodimers [Golgi membrane] (Homo sapiens)
        
        B4GALT3 homodimer [Golgi membrane] (Homo sapiens)
        
        B4GALT3 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O60512 B4GALT3

Gene Names

B4GALT3

Chain

chain:1-393

Reference Genes

BioGPS Gene:8703 B4GALT3

COSMIC (genes):B4GALT3 B4GALT3

CTD Gene:8703 B4GALT3

dbSNP Gene:8703 B4GALT3

ENSEMBL:ENSG00000158850 B4GALT3

ENSEMBL_homo_sapiens_GENE:ENSG00000158850.15 B4GALT3

HGNC:926 B4GALT3

KEGG Gene (Homo sapiens):8703 B4GALT3

Monarch:8703 B4GALT3

NCBI Gene:8703 B4GALT3

OMIM:604014 B4GALT3

UCSC:O60512 B4GALT3

Reference Transcript

Other Identifiers

11716856_a_at

16695602

210243_PM_s_at

210243_s_at

238312_PM_s_at

238312_s_at

2440665

2440666

2440667

2440669

2440671

2440674

2440676

2440677

2440678

2440680

2440681

2440682

2440683

2440685

2440686

2440694

2440695

2440696

2440697

39445_at

7921806

83744_at

8703

A_23_P103919

A_33_P3335999

GE54326

GO:0000139

GO:0003824

GO:0003831

GO:0003945

GO:0005576

GO:0005615

GO:0005794

GO:0005829

GO:0005975

GO:0006486

GO:0006629

GO:0006682

GO:0008378

GO:0016020

GO:0016740

GO:0016757

GO:0032580

GO:0036211

GO:0043226

GO:0046872

GO:0070062

GO:0070085

GO:1901135

HMNXSV003019217

Hs.157267.1.A1_3p_at

ILMN_1692267

PH_hs_0016047

g3132897_3p_s_at

Participates

as a component of

B4GALT3 homodimer [Golgi membrane] (Homo sapiens)

Inferred To

beta4GalNAcTB [Golgi membrane] (Drosophila melanogaster)

Homologues of B4GALT3 [Golgi membrane] (Drosophila melanogaster)

b4galt3 [Golgi membrane] (Xenopus tropicalis)

B4GALT3 [Golgi membrane] (Bos taurus)

B4GALT3 [Golgi membrane] (Canis familiaris)

B4GALT3 [Golgi membrane] (Gallus gallus)

B4GALT3 [Golgi membrane] (Mus musculus)

B4GALT3 [Golgi membrane] (Rattus norvegicus)

B4GALT3 [Golgi membrane] (Sus scrofa)

beta4GalNAcTA [Golgi membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_003770.1, NP_001186802.1, XP_005245623.1, NP_001186803.1

OpenTargets

ENSG00000158850

IntEnz

2.4.1.38, 2.4.1.90, 2.4.1.275

HPA

ENSG00000158850-B4GALT3

GeneCards

O60512

Ensembl

ENST00000622395, ENSG00000158850, ENSP00000320965, ENSP00000356977, ENSP00000480428, ENST00000367998, ENST00000319769

PRO

O60512

Pharos - Targets

O60512

HMDB Protein

HMDBP01032

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.527	4
UniProt:Q9H5K3 POMK	1	POMK [endoplasmic reticulum membrane] (R-HSA-8879120)	0.527	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:P27824 CANX	2	CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091) CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.527	2