Cytosolic branched-chain-amino-acid aminotransferase (BCAT1) catalyzes the reversible reactions of alpha-ketoisocaproate, alpha-keto-beta-methylvalerate, or a-ketoisovalerate with glutamate to form leucine, isoleucine, or valine, respectively, and alpha-ketoglutarate (2-oxoglutarate). The active enzyme is a homodimer (Goto et al. 2005).
Hirotsu, K, Goto, M, Islam, MM, Conway, ME, Hutson, SM, Yennawar, NH, Miyahara, I
branched-chain-amino-acid transaminase activity of BCAT1 dimer [cytosol]
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