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Our Logo
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2OG [mitochondrial matrix]
Stable Identifier
R-ALL-113594
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
2-Oxoglutarate, 2-oxoglutaric acid, Oxoglutaric acid, 2-Ketoglutaric acid, alpha-Ketoglutaric acid, 2-oxoglutarate(2-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Aspartate and asparagine metabolism (Bos taurus)
GOT2 dimer deaminates L-Asp (Bos taurus)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Bos taurus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Bos taurus)
2OG [mitochondrial matrix]
Lysine catabolism (Bos taurus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Bos taurus)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Bos taurus)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Bos taurus)
2OG [mitochondrial matrix]
Tryptophan catabolism (Bos taurus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Bos taurus)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Bos taurus)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Bos taurus)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Bos taurus)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Bos taurus)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Bos taurus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)
2OG [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Alanine metabolism (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Caenorhabditis elegans)
GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Caenorhabditis elegans)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Carnitine synthesis (Caenorhabditis elegans)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Caenorhabditis elegans)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Lysine catabolism (Caenorhabditis elegans)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Caenorhabditis elegans)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism and Citric Acid (TCA) cycle (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Caenorhabditis elegans)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Caenorhabditis elegans)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Caenorhabditis elegans)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Caenorhabditis elegans)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Caenorhabditis elegans)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter release cycle (Caenorhabditis elegans)
GABA synthesis, release, reuptake and degradation (Caenorhabditis elegans)
Degradation of GABA (Caenorhabditis elegans)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Caenorhabditis elegans)
2OG [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Aspartate and asparagine metabolism (Canis familiaris)
GOT2 dimer deaminates L-Asp (Canis familiaris)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Canis familiaris)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Canis familiaris)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Canis familiaris)
2OG [mitochondrial matrix]
Carnitine synthesis (Canis familiaris)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Canis familiaris)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Canis familiaris)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Canis familiaris)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Canis familiaris)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Canis familiaris)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Canis familiaris)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Canis familiaris)
2OG [mitochondrial matrix]
Lysine catabolism (Canis familiaris)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Canis familiaris)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Canis familiaris)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Canis familiaris)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)
2OG [mitochondrial matrix]
Tryptophan catabolism (Canis familiaris)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Canis familiaris)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Canis familiaris)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Canis familiaris)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Canis familiaris)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Canis familiaris)
Pyruvate metabolism and Citric Acid (TCA) cycle (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Canis familiaris)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Canis familiaris)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Canis familiaris)
2OG [mitochondrial matrix]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter release cycle (Canis familiaris)
GABA synthesis, release, reuptake and degradation (Canis familiaris)
Degradation of GABA (Canis familiaris)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Canis familiaris)
2OG [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Alanine metabolism (Danio rerio)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Danio rerio)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Danio rerio)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Danio rerio)
GOT2 dimer deaminates L-Asp (Danio rerio)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Danio rerio)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Danio rerio)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Danio rerio)
2OG [mitochondrial matrix]
Carnitine synthesis (Danio rerio)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Danio rerio)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Danio rerio)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Danio rerio)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Danio rerio)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Danio rerio)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Danio rerio)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Danio rerio)
2OG [mitochondrial matrix]
Lysine catabolism (Danio rerio)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Danio rerio)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Danio rerio)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Danio rerio)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Danio rerio)
2OG [mitochondrial matrix]
Tryptophan catabolism (Danio rerio)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Danio rerio)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Danio rerio)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Danio rerio)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Danio rerio)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Danio rerio)
Pyruvate metabolism and Citric Acid (TCA) cycle (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Danio rerio)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Danio rerio)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Danio rerio)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Danio rerio)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Danio rerio)
2OG [mitochondrial matrix]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter release cycle (Danio rerio)
GABA synthesis, release, reuptake and degradation (Danio rerio)
Degradation of GABA (Danio rerio)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Danio rerio)
2OG [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Alanine metabolism (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Dictyostelium discoideum)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Dictyostelium discoideum)
GOT2 dimer deaminates L-Asp (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Dictyostelium discoideum)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Dictyostelium discoideum)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Lysine catabolism (Dictyostelium discoideum)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Dictyostelium discoideum)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Dictyostelium discoideum)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Tryptophan catabolism (Dictyostelium discoideum)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Dictyostelium discoideum)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Dictyostelium discoideum)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Dictyostelium discoideum)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Dictyostelium discoideum)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Neuronal System (Dictyostelium discoideum)
Transmission across Chemical Synapses (Dictyostelium discoideum)
Neurotransmitter release cycle (Dictyostelium discoideum)
GABA synthesis, release, reuptake and degradation (Dictyostelium discoideum)
Degradation of GABA (Dictyostelium discoideum)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Dictyostelium discoideum)
2OG [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Alanine metabolism (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Drosophila melanogaster)
GOT2 dimer deaminates L-Asp (Drosophila melanogaster)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Drosophila melanogaster)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Drosophila melanogaster)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Drosophila melanogaster)
2OG [mitochondrial matrix]
Carnitine synthesis (Drosophila melanogaster)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Drosophila melanogaster)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Drosophila melanogaster)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Drosophila melanogaster)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Drosophila melanogaster)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Drosophila melanogaster)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Drosophila melanogaster)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Drosophila melanogaster)
2OG [mitochondrial matrix]
Lysine catabolism (Drosophila melanogaster)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Drosophila melanogaster)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Drosophila melanogaster)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Drosophila melanogaster)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Drosophila melanogaster)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism and Citric Acid (TCA) cycle (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Drosophila melanogaster)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Drosophila melanogaster)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Drosophila melanogaster)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Drosophila melanogaster)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Drosophila melanogaster)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Drosophila melanogaster)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Drosophila melanogaster)
2OG [mitochondrial matrix]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter release cycle (Drosophila melanogaster)
GABA synthesis, release, reuptake and degradation (Drosophila melanogaster)
Degradation of GABA (Drosophila melanogaster)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Drosophila melanogaster)
2OG [mitochondrial matrix]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Alanine metabolism (Gallus gallus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Gallus gallus)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Gallus gallus)
2OG [mitochondrial matrix]
Carnitine synthesis (Gallus gallus)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Gallus gallus)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Gallus gallus)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Gallus gallus)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Gallus gallus)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Gallus gallus)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Gallus gallus)
2OG [mitochondrial matrix]
Lysine catabolism (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Gallus gallus)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Gallus gallus)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Gallus gallus)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Gallus gallus)
2OG [mitochondrial matrix]
Tryptophan catabolism (Gallus gallus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Gallus gallus)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Gallus gallus)
Glucose metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Gallus gallus)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Gallus gallus)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Gallus gallus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Gallus gallus)
Citric acid cycle (TCA cycle) (Gallus gallus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Gallus gallus)
2OG [mitochondrial matrix]
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Gallus gallus)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Gallus gallus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Gallus gallus)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Gallus gallus)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Gallus gallus)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Gallus gallus)
2OG [mitochondrial matrix]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter release cycle (Gallus gallus)
GABA synthesis, release, reuptake and degradation (Gallus gallus)
Degradation of GABA (Gallus gallus)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Gallus gallus)
2OG [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Alanine metabolism (Homo sapiens)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Homo sapiens)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Homo sapiens)
GOT2 dimer deaminates L-Asp (Homo sapiens)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Homo sapiens)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Homo sapiens)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Homo sapiens)
2OG [mitochondrial matrix]
Carnitine synthesis (Homo sapiens)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Homo sapiens)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Homo sapiens)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Homo sapiens)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Homo sapiens)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Homo sapiens)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Homo sapiens)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Homo sapiens)
2OG [mitochondrial matrix]
Lysine catabolism (Homo sapiens)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Homo sapiens)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Homo sapiens)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Homo sapiens)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)
2OG [mitochondrial matrix]
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu (Homo sapiens)
2OG [mitochondrial matrix]
Tryptophan catabolism (Homo sapiens)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Homo sapiens)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Homo sapiens)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Homo sapiens)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Homo sapiens)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
Pyruvate metabolism and Citric Acid (TCA) cycle (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Homo sapiens)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Homo sapiens)
2OG [mitochondrial matrix]
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Homo sapiens)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Homo sapiens)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Homo sapiens)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Homo sapiens)
2OG [mitochondrial matrix]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
GABA synthesis, release, reuptake and degradation (Homo sapiens)
Degradation of GABA (Homo sapiens)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Homo sapiens)
2OG [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Alanine metabolism (Mus musculus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Mus musculus)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Mus musculus)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Mus musculus)
GOT2 dimer deaminates L-Asp (Mus musculus)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Mus musculus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Mus musculus)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Mus musculus)
2OG [mitochondrial matrix]
Carnitine synthesis (Mus musculus)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Mus musculus)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Mus musculus)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Mus musculus)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Mus musculus)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Mus musculus)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Mus musculus)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Mus musculus)
2OG [mitochondrial matrix]
Lysine catabolism (Mus musculus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Mus musculus)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Mus musculus)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Mus musculus)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)
2OG [mitochondrial matrix]
Tryptophan catabolism (Mus musculus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Mus musculus)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Mus musculus)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Mus musculus)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Mus musculus)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Mus musculus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Mus musculus)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Mus musculus)
2OG [mitochondrial matrix]
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Mus musculus)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Mus musculus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Mus musculus)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Mus musculus)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Mus musculus)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Mus musculus)
2OG [mitochondrial matrix]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter release cycle (Mus musculus)
GABA synthesis, release, reuptake and degradation (Mus musculus)
Degradation of GABA (Mus musculus)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Mus musculus)
2OG [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Aspartate and asparagine metabolism (Plasmodium falciparum)
GOT2 dimer deaminates L-Asp (Plasmodium falciparum)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Plasmodium falciparum)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Plasmodium falciparum)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Plasmodium falciparum)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Plasmodium falciparum)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Plasmodium falciparum)
Glucose metabolism (Plasmodium falciparum)
Gluconeogenesis (Plasmodium falciparum)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Plasmodium falciparum)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Plasmodium falciparum)
2OG [mitochondrial matrix]
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Plasmodium falciparum)
2OG [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Alanine metabolism (Rattus norvegicus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Rattus norvegicus)
GOT2 dimer deaminates L-Asp (Rattus norvegicus)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Rattus norvegicus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Rattus norvegicus)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Rattus norvegicus)
2OG [mitochondrial matrix]
Carnitine synthesis (Rattus norvegicus)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Rattus norvegicus)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Rattus norvegicus)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Rattus norvegicus)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Rattus norvegicus)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Rattus norvegicus)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Rattus norvegicus)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Rattus norvegicus)
2OG [mitochondrial matrix]
Lysine catabolism (Rattus norvegicus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Rattus norvegicus)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Rattus norvegicus)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Rattus norvegicus)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)
2OG [mitochondrial matrix]
Tryptophan catabolism (Rattus norvegicus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Rattus norvegicus)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Rattus norvegicus)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Rattus norvegicus)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Rattus norvegicus)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Rattus norvegicus)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Rattus norvegicus)
2OG [mitochondrial matrix]
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Rattus norvegicus)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Rattus norvegicus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Rattus norvegicus)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Rattus norvegicus)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Rattus norvegicus)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Rattus norvegicus)
2OG [mitochondrial matrix]
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter release cycle (Rattus norvegicus)
GABA synthesis, release, reuptake and degradation (Rattus norvegicus)
Degradation of GABA (Rattus norvegicus)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Rattus norvegicus)
2OG [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Alanine metabolism (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Saccharomyces cerevisiae)
GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Saccharomyces cerevisiae)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Lysine catabolism (Saccharomyces cerevisiae)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism and Citric Acid (TCA) cycle (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Saccharomyces cerevisiae)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Neuronal System (Saccharomyces cerevisiae)
Transmission across Chemical Synapses (Saccharomyces cerevisiae)
Neurotransmitter release cycle (Saccharomyces cerevisiae)
GABA synthesis, release, reuptake and degradation (Saccharomyces cerevisiae)
Degradation of GABA (Saccharomyces cerevisiae)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Saccharomyces cerevisiae)
2OG [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Alanine metabolism (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Aspartate and asparagine metabolism (Schizosaccharomyces pombe)
GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Branched-chain amino acid catabolism (Schizosaccharomyces pombe)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Lysine catabolism (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism and Citric Acid (TCA) cycle (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Schizosaccharomyces pombe)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Neuronal System (Schizosaccharomyces pombe)
Transmission across Chemical Synapses (Schizosaccharomyces pombe)
Neurotransmitter release cycle (Schizosaccharomyces pombe)
GABA synthesis, release, reuptake and degradation (Schizosaccharomyces pombe)
Degradation of GABA (Schizosaccharomyces pombe)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Schizosaccharomyces pombe)
2OG [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Alanine metabolism (Sus scrofa)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)
2OG [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Sus scrofa)
2OG [mitochondrial matrix]
Carnitine synthesis (Sus scrofa)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Sus scrofa)
2OG [mitochondrial matrix]
Glutamate and glutamine metabolism (Sus scrofa)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Sus scrofa)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Sus scrofa)
2OG [mitochondrial matrix]
Lysine catabolism (Sus scrofa)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Sus scrofa)
2OG [mitochondrial matrix]
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Sus scrofa)
2OG [mitochondrial matrix]
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Sus scrofa)
2OG [mitochondrial matrix]
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)
2OG [mitochondrial matrix]
Tryptophan catabolism (Sus scrofa)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Sus scrofa)
2OG [mitochondrial matrix]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Sus scrofa)
2OG [mitochondrial matrix]
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Sus scrofa)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Sus scrofa)
Pyruvate metabolism and Citric Acid (TCA) cycle (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Sus scrofa)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Sus scrofa)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)
2OG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Sus scrofa)
2OG [mitochondrial matrix]
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Sus scrofa)
2OG [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Glutamate and glutamine metabolism (Xenopus tropicalis)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Xenopus tropicalis)
2OG [mitochondrial matrix]
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Xenopus tropicalis)
2OG [mitochondrial matrix]
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Xenopus tropicalis)
2OG [mitochondrial matrix]
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Xenopus tropicalis)
2OG [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism and Citric Acid (TCA) cycle (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Xenopus tropicalis)
2OG [mitochondrial matrix]
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Xenopus tropicalis)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Xenopus tropicalis)
2OG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Xenopus tropicalis)
2OG [mitochondrial matrix]
External Reference Information
External Reference
2-oxoglutarate(2-) [ChEBI:16810]
Participates
as an input of
2-oxoglutarate (alpha-ketoglutarate) + CoASH + NAD+ => succinylCoA + CO2 + NADH + H+ (Gallus gallus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Caenorhabditis elegans)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Canis familiaris)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Dictyostelium discoideum)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Drosophila melanogaster)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Danio rerio)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Gallus gallus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Homo sapiens)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Mus musculus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Rattus norvegicus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Sus scrofa)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Xenopus tropicalis)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Bos taurus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Caenorhabditis elegans)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Canis familiaris)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Dictyostelium discoideum)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Drosophila melanogaster)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Danio rerio)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Gallus gallus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Homo sapiens)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Mus musculus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Rattus norvegicus)
2-oxoglutarate [mitochondrial matrix] + 2-oxoadipate [cytosol] <=> 2-oxoglutarate [cytosol] + 2-oxoadipate [mitochondrial matrix] (Sus scrofa)
2-oxoglutarate [mitochondrial matrix] + malate [cytosol] <=> 2-oxoglutarate [cytosol] + malate [mitochondrial matrix] (Gallus gallus)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Bos taurus)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Canis familiaris)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Dictyostelium discoideum)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Danio rerio)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Gallus gallus)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Homo sapiens)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Mus musculus)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Rattus norvegicus)
alpha-aminoadipate + alpha-ketoglutarate <=> alpha-ketoadipate + glutamate (Sus scrofa)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Caenorhabditis elegans)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Dictyostelium discoideum)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Drosophila melanogaster)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Danio rerio)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Gallus gallus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Homo sapiens)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Mus musculus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Plasmodium falciparum)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Rattus norvegicus)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Saccharomyces cerevisiae)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Schizosaccharomyces pombe)
alpha-ketoglutarate + CoASH + NAD+ => succinyl-CoA + CO2 + NADH + H+ (Sus scrofa)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Caenorhabditis elegans)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Canis familiaris)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Dictyostelium discoideum)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Drosophila melanogaster)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Danio rerio)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Gallus gallus)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Homo sapiens)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Mus musculus)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Rattus norvegicus)
alpha-ketoglutarate + NH4+ + NAD(P)H + H+ <=> glutamate + NAD(P)+ [GLUD1] (Xenopus tropicalis)
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Bos taurus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Caenorhabditis elegans)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Canis familiaris)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Dictyostelium discoideum)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Drosophila melanogaster)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Danio rerio)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Gallus gallus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Homo sapiens)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Mus musculus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Rattus norvegicus)
Exchange of alpha-ketoglutarate (2-oxoglutarate) and malate across the inner mitochondrial membrane (Sus scrofa)
GOT2 dimer deaminates L-Asp (Bos taurus)
GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)
GOT2 dimer deaminates L-Asp (Canis familiaris)
GOT2 dimer deaminates L-Asp (Dictyostelium discoideum)
GOT2 dimer deaminates L-Asp (Drosophila melanogaster)
GOT2 dimer deaminates L-Asp (Danio rerio)
GOT2 dimer deaminates L-Asp (Homo sapiens)
GOT2 dimer deaminates L-Asp (Mus musculus)
GOT2 dimer deaminates L-Asp (Plasmodium falciparum)
GOT2 dimer deaminates L-Asp (Rattus norvegicus)
GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)
GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)
GOT2 dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu (Homo sapiens)
Got2:PLXP dimer transfers amino group from L-Cys to 2OG to form 3MPYR and Glu (Rattus norvegicus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Bos taurus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Canis familiaris)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Dictyostelium discoideum)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Danio rerio)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Gallus gallus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Homo sapiens)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Mus musculus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Rattus norvegicus)
kynurenine + 2-oxoglutarate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + glutamate (Sus scrofa)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Caenorhabditis elegans)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Canis familiaris)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Dictyostelium discoideum)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Drosophila melanogaster)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Danio rerio)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Homo sapiens)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Mus musculus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Rattus norvegicus)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Saccharomyces cerevisiae)
leu, ile, or val + alpha-ketoglutarate <=> a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate [BCAT2] (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Dictyostelium discoideum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Danio rerio)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Gallus gallus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Saccharomyces cerevisiae)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Caenorhabditis elegans)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Canis familiaris)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Dictyostelium discoideum)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Drosophila melanogaster)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Danio rerio)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Gallus gallus)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Homo sapiens)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Mus musculus)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Plasmodium falciparum)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Rattus norvegicus)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Saccharomyces cerevisiae)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Schizosaccharomyces pombe)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Sus scrofa)
ornithine + alpha-ketoglutarate <=> glutamate + L-glutamate gamma-semialdehyde [OAT] (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Danio rerio)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Gallus gallus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Homo sapiens)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Mus musculus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Caenorhabditis elegans)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Canis familiaris)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Dictyostelium discoideum)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Drosophila melanogaster)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Danio rerio)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Gallus gallus)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Homo sapiens)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Mus musculus)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Rattus norvegicus)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Saccharomyces cerevisiae)
PXLP-K357-ABAT dimer:2Fe-2S transforms GABA to SUCCSA (Schizosaccharomyces pombe)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Caenorhabditis elegans)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Canis familiaris)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Drosophila melanogaster)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Danio rerio)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Gallus gallus)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Homo sapiens)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Mus musculus)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Rattus norvegicus)
TMLHE dimer dioxygenates TMLYS and 2OG to form HTMLYS and SUCCA (Sus scrofa)
as an output of
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Caenorhabditis elegans)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Drosophila melanogaster)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Gallus gallus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Mus musculus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Rattus norvegicus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Saccharomyces cerevisiae)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Schizosaccharomyces pombe)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Caenorhabditis elegans)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Dictyostelium discoideum)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Drosophila melanogaster)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Danio rerio)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Gallus gallus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Homo sapiens)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Mus musculus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Rattus norvegicus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Sus scrofa)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Xenopus tropicalis)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Caenorhabditis elegans)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Drosophila melanogaster)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Gallus gallus)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Mus musculus)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Rattus norvegicus)
(S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Caenorhabditis elegans)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Canis familiaris)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Dictyostelium discoideum)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Drosophila melanogaster)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Danio rerio)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Homo sapiens)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Mus musculus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Rattus norvegicus)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Saccharomyces cerevisiae)
a-ketoisocaproate, a-keto-b-methylvalerate, or a-ketoisovalerate + glutamate <=> leu, ile, or val + alpha-ketoglutarate [BCAT2] (Schizosaccharomyces pombe)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Bos taurus)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Canis familiaris)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Dictyostelium discoideum)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Danio rerio)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Gallus gallus)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Homo sapiens)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Mus musculus)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Rattus norvegicus)
alpha-ketoadipate + glutamate <=> alpha-aminoadipate + alpha-ketoglutarate (Sus scrofa)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Caenorhabditis elegans)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Canis familiaris)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Dictyostelium discoideum)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Drosophila melanogaster)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Danio rerio)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Gallus gallus)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Homo sapiens)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Mus musculus)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Plasmodium falciparum)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Rattus norvegicus)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Saccharomyces cerevisiae)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Schizosaccharomyces pombe)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Sus scrofa)
glutamate + L-glutamate gamma-semialdehyde <=> ornithine + alpha-ketoglutarate [OAT] (Xenopus tropicalis)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Caenorhabditis elegans)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Canis familiaris)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Dictyostelium discoideum)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Drosophila melanogaster)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Danio rerio)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Gallus gallus)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Homo sapiens)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Mus musculus)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Rattus norvegicus)
glutamate + NAD(P)+ => alpha-ketoglutarate + NH4+ + NAD(P)H + H+ [GLUD1] (Xenopus tropicalis)
isocitrate + NAD+ => 2-oxoglutarate (alpha-ketoglutarate) + CO2 + NADH + H+ (Gallus gallus)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Caenorhabditis elegans)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Dictyostelium discoideum)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Drosophila melanogaster)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Danio rerio)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Homo sapiens)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Mus musculus)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Rattus norvegicus)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Saccharomyces cerevisiae)
isocitrate + NAD+ => alpha-ketoglutarate + CO2 + NADH + H+ [IDH3] (Schizosaccharomyces pombe)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Bos taurus)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Caenorhabditis elegans)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Canis familiaris)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Gallus gallus)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Homo sapiens)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Mus musculus)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Plasmodium falciparum)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Rattus norvegicus)
isocitrate + NADP+ => alpha-ketoglutarate + CO2 + NADPH + H+ [IDH2] (Xenopus tropicalis)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Bos taurus)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Caenorhabditis elegans)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Canis familiaris)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Dictyostelium discoideum)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Drosophila melanogaster)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Danio rerio)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Gallus gallus)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Homo sapiens)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Mus musculus)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Rattus norvegicus)
malate [mitochondrial matrix] + alpha-ketoglutarate [cytosol] <=> malate [cytosol] + alpha-ketoglutarate [mitochondrial matrix] (Sus scrofa)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Bos taurus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Caenorhabditis elegans)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Canis familiaris)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Dictyostelium discoideum)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Drosophila melanogaster)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Danio rerio)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Homo sapiens)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Mus musculus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Plasmodium falciparum)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Rattus norvegicus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Saccharomyces cerevisiae)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate [GOT2] (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Danio rerio)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Gallus gallus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Mus musculus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Sus scrofa)
Other forms of this molecule
2OG [cytoplasm]
2OG [endoplasmic reticulum lumen]
2OG [peroxisomal matrix]
2OG [nucleoplasm]
2OG [cytosol]
2OG [extracellular region]
Cross References
KNApSAcK
C00000769
AraCyc
2-KETOGLUTARATE
PubChem
164533
CAS
328-50-7
COMPOUND
C00026
KEGG Gene
C00026
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![2OG [mitochondrial matrix] icon](/icon/R-ICO-012365.svg){kind=icon}
