PXLP-K200-PSAT1 dimer transfers amino group from L-Glu to 3POPA

Stable Identifier
R-HSA-977333
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
3-phosphonooxypyruvic acid + L-glutamate = O-phospho-L-serine + 2-oxoglutarate
ReviewStatus
5/5
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The amino group needed for serine biosynthesis comes from glutamate (L-Glu). Its transfer onto 3-phosphonooxpyruvate (3POPA) is catalysed by PSAT1 dimer which needs pyridoxal phosphate (PXLP) as cofactor. (Baek et al. 2003)
Literature References
PubMed ID Title Journal Year
12633500 Characterization of human phosphoserine aminotransferase involved in the phosphorylated pathway of L-serine biosynthesis

Baek, JY, Jun, DY, Kim, YH, Taub, D

Biochem J 2003
Participants
Participates
Catalyst Activity

O-phospho-L-serine:2-oxoglutarate aminotransferase activity of PXLP-K200-PSAT1 dimer [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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