Graph Database :: Data Schema
Graph Database :: Data Schema
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DatabaseObject
- AbstractModifiedResidue [53211]
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Affiliation
[346]
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CatalystActivity
[38657]
- ControlReference [3115]
- ControlledVocabulary [21]
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DatabaseIdentifier
[649627]
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EntityFunctionalStatus
[690]
- Event [115012]
- ExternalOntology [981]
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Figure
[879]
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FunctionalStatus
[27]
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FunctionalStatusType
[5]
- GO_Term [3033]
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InstanceEdit
[148017]
- Interaction [71815]
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MetaDatabaseObject
[76624]
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Deleted
[7481]
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DeletedInstance
[10182]
- Release [139]
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UpdateTracker
[58822]
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Deleted
[7481]
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NegativePrecedingEvent
[556]
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Person
[163938]
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PhysicalEntity
[399186]
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Cell
[15]
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Complex
[106900]
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Drug
[1144]
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ChemicalDrug
[1053]
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ProteinDrug
[90]
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RNADrug
[1]
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ChemicalDrug
[1053]
- EntitySet [43924]
- GenomeEncodedEntity [241559]
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OtherEntity
[345]
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Polymer
[1523]
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SimpleEntity
[3776]
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Cell
[15]
- Publication [40501]
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ReferenceDatabase
[104]
- ReferenceEntity [813113]
- Regulation [7317]
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Summation
[20688]
- Taxon [400]
Entries: FailedReaction
Select species:
| Identifier | Name |
|---|---|
| R-HSA-9915356 | ACAT1 mutants don't synthesize propionyl-CoA or acetyl-CoA |
| R-HSA-9824402 | ADAMTS13 variant does not cleave VWF multimer |
| R-HSA-5246696 | APC truncation mutants are not K63 polyubiquitinated |
| R-HSA-4791278 | APC truncation mutants have impaired AXIN binding |
| R-HSA-9700646 | ASP-3026- resistant ALK mutants don't bind ASP-3026 |
| R-HSA-9914271 | AUH mutants don't synthesize 3-hydroxy-methylglutaryl-CoA |
| R-HSA-4839734 | AXIN mutants destabilize the destruction complex |
| R-HSA-3304394 | Activated TGFBR1 cannot phosphorylate SMAD2 and SMAD3 Phosphorylation Motif Mutants |
| R-HSA-9005561 | Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308 |
| R-HSA-3656523 | An anchoring protein ZFYVE9 (SARA) does not recruit SMAD2/3 to TGFB1:TGFBR2:p-TGFBR1 KD Mutants |
| R-HSA-9865121 | BCKDHA or BCKDHB loss-of-function mutants don't synthesize BCAA-CoA |
| R-HSA-9912480 | BCKDK loss-of-function mutations do not phosphorylate BCKDH |
| R-HSA-9763200 | BRCA2 mutants do not bind SEM1 (DSS1) |
| R-HSA-9709571 | BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 |
| R-HSA-9706356 | CBL mutants don't ubiquitinate FLT3 |
| R-HSA-9656207 | CR2 RAF1 mutants don't bind YWHAB |
| R-HSA-4839634 | CTNNB1 S33 mutants aren't phosphorylated by GSK3beta |
| R-HSA-4839635 | CTNNB1 S37 mutants aren't phosphorylated by GSK3beta |
| R-HSA-4827388 | CTNNB1 S45 mutants aren't phosphorylated by CK1alpha |
| R-HSA-4839638 | CTNNB1 T41 mutants aren't phosphorylated by GSK3beta |
| R-HSA-5602170 | CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol |
| R-HSA-9652816 | Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs |
| R-HSA-9674398 | D842V PDGFRA doesn't bind sunitinib |
| R-HSA-9865115 | DBT loss-of-function mutants don't synthesize BCAA-CoA |
| R-HSA-9669855 | Dasatinib-resistant KIT mutants do not bind dasatinib |
| R-HSA-5682111 | Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane |
| R-HSA-5682311 | Defective ABCA12 does not transport lipids from cytosol to extracellular region |
| R-HSA-5688397 | Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body |
| R-HSA-5683672 | Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body |
| R-HSA-2466802 | Defective ABCA4 does not transport NRPE from disc membranes |
| R-HSA-5678517 | Defective ABCB11 does not transport bile salts from cytosol to extracellular region |
| R-HSA-5678749 | Defective ABCB4 does not transport PC from plasma membrane to extracellular region |
| R-HSA-5683355 | Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix |
| R-HSA-5679031 | Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region |
| R-HSA-5690340 | Defective ABCC6 does not transport organic anion from cytosol to extracellular region |
| R-HSA-5683113 | Defective ABCC8 does not form functional KATP channels, causing hyperinsulinemic hypoglycemia |
| R-HSA-5678418 | Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol |
| R-HSA-5684043 | Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix |
| R-HSA-5683325 | Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol |
| R-HSA-5679145 | Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region |
| R-HSA-5679101 | Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region |
| R-HSA-5603251 | Defective ACTH does not bind MCR2 |
| R-HSA-5579081 | Defective ACY1 does not hydrolyse mercapturic acids |
| R-HSA-9734745 | Defective ADA does not deaminate (deoxy)adenosine |
| R-HSA-5579084 | Defective AHCY does not hydrolyse AdoHcy |
| R-HSA-5656438 | Defective ALDOB does not cleave Fru 1-P to GA and DHAP |
| R-HSA-4549382 | Defective ALG1 does not transfer the first Man to the N-glycan precursor |
| R-HSA-4551297 | Defective ALG11 does not transfer Man to the N-glycan precursor |
| R-HSA-4720497 | Defective ALG12 does not add mannose to the N-glycan precursor |
| R-HSA-5633241 | Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP |
| R-HSA-4549368 | Defective ALG2 does not transfer a second Man to N-glycan precursor |
| R-HSA-4720473 | Defective ALG3 does not add mannose to the N-glycan precursor |
| R-HSA-4724291 | Defective ALG6 does not add glucose to the N-glycan precursor |
| R-HSA-4724330 | Defective ALG8 does not add glucose to the N-glycan precursor |
| R-HSA-9035514 | Defective ALG9 does not add the last mannose to the N-glycan precursor |
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