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Graph Database :: Data Schema

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Entries: FailedReaction
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Identifier Name
R-HSA-9824402 ADAMTS13 variant does not cleave VWF multimer
R-HSA-5246696 APC truncation mutants are not K63 polyubiquitinated
R-HSA-4791278 APC truncation mutants have impaired AXIN binding
R-HSA-9700646 ASP-3026- resistant ALK mutants don't bind ASP-3026
R-HSA-4839734 AXIN mutants destabilize the destruction complex
R-HSA-3304394 Activated TGFBR1 cannot phosphorylate SMAD2 and SMAD3 Phosphorylation Motif Mutants
R-HSA-9005561 Active PKA, CaMK IV do not phosphorylate MECP2 mutants R306C,(R306H) at T308
R-HSA-3656523 An anchoring protein ZFYVE9 (SARA) does not recruit SMAD2/3 to TGFB1:TGFBR2:p-TGFBR1 KD Mutants
R-HSA-9763200 BRCA2 mutants do not bind SEM1 (DSS1)
R-HSA-9709571 BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51
R-HSA-9706356 CBL mutants don't ubiquitinate FLT3
R-HSA-9656207 CR2 RAF1 mutants don't bind YWHAB
R-HSA-4839634 CTNNB1 S33 mutants aren't phosphorylated by GSK3beta
R-HSA-4839635 CTNNB1 S37 mutants aren't phosphorylated by GSK3beta
R-HSA-4827388 CTNNB1 S45 mutants aren't phosphorylated by CK1alpha
R-HSA-4839638 CTNNB1 T41 mutants aren't phosphorylated by GSK3beta
R-HSA-5602170 CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol
R-HSA-9652816 Constitutively active MAPK1 mutants are not dephosphorylated by DUSPs
R-HSA-9674398 D842V PDGFRA doesn't bind sunitinib
R-HSA-9669855 Dasatinib-resistant KIT mutants do not bind dasatinib
R-HSA-5682111 Defective ABCA1 does not transport CHOL from transport vesicle membrane to plasma membrane
R-HSA-5682311 Defective ABCA12 does not transport lipids from cytosol to extracellular region
R-HSA-5683672 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body
R-HSA-5688397 Defective ABCA3 does not transport PC, PG from ER membrane to lamellar body
R-HSA-2466802 Defective ABCA4 does not transport NRPE from disc membranes
R-HSA-5678517 Defective ABCB11 does not transport bile salts from cytosol to extracellular region
R-HSA-5678749 Defective ABCB4 does not transport PC from plasma membrane to extracellular region
R-HSA-5683355 Defective ABCB6 does not transport porphyrin from cytosol into mitochondria matrix
R-HSA-5679031 Defective ABCC2 does not transport BMG,BDG from cytosol to extracellular region
R-HSA-5690340 Defective ABCC6 does not transport organic anion from cytosol to extracellular region
R-HSA-5683113 Defective ABCC8 does not form functional KATP channels, causing hyperinsulinemic hypoglycemia
R-HSA-5678418 Defective ABCC9 (in KCNJ11:ABCC9) does not transport K+ from extracellular region to cytosol
R-HSA-5684043 Defective ABCD1 does not transfer LCFAs from cytosol to peroxisomal matrix
R-HSA-5683325 Defective ABCD4:LMBRD1 does not transport Cbl from lysosomal lumen to cytosol
R-HSA-5679145 Defective ABCG5 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region
R-HSA-5679101 Defective ABCG8 (in ABCG5:ABCG8) does not transport sterols from cytosol to extracellular region
R-HSA-5603251 Defective ACTH does not bind MCR2
R-HSA-5579081 Defective ACY1 does not hydrolyse mercapturic acids
R-HSA-9734745 Defective ADA does not deaminate (deoxy)adenosine
R-HSA-5579084 Defective AHCY does not hydrolyse AdoHcy
R-HSA-5656438 Defective ALDOB does not cleave Fru 1-P to GA and DHAP
R-HSA-4549382 Defective ALG1 does not transfer the first Man to the N-glycan precursor
R-HSA-4551297 Defective ALG11 does not transfer Man to the N-glycan precursor
R-HSA-4720497 Defective ALG12 does not add mannose to the N-glycan precursor
R-HSA-5633241 Defective ALG14 does not transfer GlcNAc from UDP-GlcNAc to GlcNAcDOLP
R-HSA-4549368 Defective ALG2 does not transfer a second Man to N-glycan precursor
R-HSA-4720473 Defective ALG3 does not add mannose to the N-glycan precursor
R-HSA-4724291 Defective ALG6 does not add glucose to the N-glycan precursor
R-HSA-4724330 Defective ALG8 does not add glucose to the N-glycan precursor
R-HSA-9035514 Defective ALG9 does not add the last mannose to the N-glycan precursor
R-HSA-4720478 Defective ALG9 does not add the seventh mannose to the N-glycan precursor
R-HSA-3296477 Defective AMN does not transport GIF:Cbl
R-HSA-9734193 Defective APRT does not convert adenine to AMP
R-HSA-2282889 Defective ARSB does not hydrolyse C4S/C6S chains
R-HSA-9036065 Defective ARSB does not hydrolyse DS
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