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Entries: RegulationReference
Identifier Name
9642964 Negative gene expression regulation by '(p-S451-RUNX2:CBFB,RUNX2:CBFB,RUNX2:HDAC6):CDKN1A gene [nucleoplasm]' Glucose-activated RUNX2 phosphorylation promotes endothelial cell proliferation and an angiogenic phenotype
9641570 Negative gene expression regulation by '2x(p-STAT5A,p-STAT5B):BRWD1 gene [nucleoplasm]' Histone reader BRWD1 targets and restricts recombination to the Igk locus
9641613 Negative gene expression regulation by 'CREM:PER1 gene [nucleoplasm]' Inducible cAMP early repressor regulates the Period 1 gene of the hepatic and adrenal clocks
9641730 Negative gene expression regulation by 'CRHR2:UCN(83-122) [plasma membrane]' Urocortin 1 reduces food intake and ghrelin secretion via CRF(2) receptors
9642802 Negative gene expression regulation by 'DREAM complex:CDC25A gene [nucleoplasm]' Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
9641835 Negative gene expression regulation by 'DREAM complex:CDC6 gene [nucleoplasm]' Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
9642011 Negative gene expression regulation by 'DREAM complex:E2F1 gene [nucleoplasm]' Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
9642359 Negative gene expression regulation by 'DREAM complex:PCNA gene [nucleoplasm]' Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
9641974 Negative gene expression regulation by 'DREAM complex:RBL1 gene [nucleoplasm]' Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
9642902 Negative gene expression regulation by 'DREAM complex:TOP2A gene [nucleoplasm]' Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence
9641265 Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):APAF1 gene [nucleoplasm]' E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1
9643017 Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):BRCA1 gene [nucleoplasm]' E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
9642627 Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):CBX5 gene [nucleoplasm]' E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
9642014 Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):RAD51 gene [nucleoplasm]' Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
9641954 Negative gene expression regulation by 'E2F6:(TFDP1,TFDP2):RBBP4 gene [nucleoplasm]' E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
9641693 Negative gene expression regulation by 'E2F6:(TFDP1.TFDP2):RBBP8 gene [nucleoplasm]' E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9
9642139 Negative gene expression regulation by 'E2F6:TFDP1/2,(E2F6:TFDP1:MGA:MAX:EHMT1:EHMT2:CBX3:PRC1.6) [nucleoplasm]' A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells
9641666 Negative gene expression regulation by 'E2F7,E2F8 dimers:E2F1 Gene [nucleoplasm]' E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression
9642932 Negative gene expression regulation by 'EGR2 [nucleoplasm]' PIASxbeta acts as an activator of Hoxb1 and is antagonized by Krox20 during hindbrain segmentation
9642410 Negative gene expression regulation by 'EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm]' The p400 E1A-associated protein is a novel component of the p53 --> p21 senescence pathway
9642854 Negative gene expression regulation by 'ERBB4s80:TAB2:NCOR1:GFAP gene [nucleoplasm]' Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain
9641839 Negative gene expression regulation by 'ERBB4s80:TAB2:NCOR1:S100B gene [nucleoplasm]' Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain
9642650 Negative gene expression regulation by 'ERF:ETS2 Gene [nucleoplasm]' ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
9641582 Negative gene expression regulation by 'ESR1:estrogen:AXIN1 gene [nucleoplasm]' RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer
9643014 Negative gene expression regulation by 'ESRRA:PPARG1CB:RUNX2 gene [nucleoplasm]' Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform
9642206 Negative gene expression regulation by 'Glucocorticoid ligand:NR3C1:RUNX2 gene [nucleoplasm]' Down-regulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis
9642954 Negative gene expression regulation by 'HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CCNA2 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9641640 Negative gene expression regulation by 'HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:CDK1 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9641575 Negative gene expression regulation by 'HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:E2F1 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9641316 Negative gene expression regulation by 'HDAC1:RBL2:E2F4,E2F5:TFDP1,TFDP2; HDAC1:RBL1:E2F4:TFDP1,TFDP2:MYBL2 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9642189 Negative gene expression regulation by 'HOXB3 [nucleoplasm]' Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning
9641427 Negative gene expression regulation by 'Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:Ccna2 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9641229 Negative gene expression regulation by 'Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:Cdk1 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9642989 Negative gene expression regulation by 'Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:E2f1 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9642204 Negative gene expression regulation by 'Hdac1:Rbl2:E2f4,E2f5:Tfdp1,Tfdp2; Hdac1:Rbl1:E2f4:Tfdp1,Tfdp2:Mybl2 gene [nucleoplasm]' E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex
9641389 Negative gene expression regulation by 'Ik1:Ptcra gene [nucleoplasm]' Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing
9643022 Negative gene expression regulation by 'JUN:PTEN gene [nucleoplasm]' Suppression of PTEN expression is essential for antiapoptosis and cellular transformation by oncogenic Ras
9642718 Negative gene expression regulation by 'KSRP:mRNA Degradation Complex [cytosol]' IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR
9641914 Negative gene expression regulation by 'Lhx2:Robo1 gene [nucleoplasm]' The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors
9642467 Negative gene expression regulation by 'Lhx2:Robo2 gene [nucleoplasm]' The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors
9642379 Negative gene expression regulation by 'MECOM:(PRC1.4,PRC2 (EZH2) core):PTEN gene [nucleoplasm]' Evi1 represses PTEN expression and activates PI3K/AKT/mTOR via interactions with polycomb proteins
9641810 Negative gene expression regulation by 'MECP2:PTPN1 gene [nucleoplasm]' PTP1B inhibition suggests a therapeutic strategy for Rett syndrome
9642881 Negative gene expression regulation by 'MECP2:SIN3A:HDAC1:BDNF gene [nucleoplasm]' DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
9642654 Negative gene expression regulation by 'MSX2:RUNX2 gene [nucleoplasm]' Dlx5 specifically regulates Runx2 type II expression by binding to homeodomain-response elements in the Runx2 distal promoter
9641892 Negative gene expression regulation by 'MTF1 dimer:12Zn2+:HMGCR gene [nucleoplasm]' Comparative analysis of MTF-1 binding sites between human and mouse
9641856 Negative gene expression regulation by 'MYC gene:CEBPA:E2F1:(TFDP1,TFDP2) [nucleoplasm]' The amino terminal and E2F interaction domains are critical for C/EBP alpha-mediated induction of granulopoietic development of hematopoietic cells
9641715 Negative gene expression regulation by 'Mecp2 mRNA:miR-132 RISC [cytosol]' MeCP2 controls hippocampal brain-derived neurotrophic factor expression via homeostatic interactions with microRNA‑132 in rats with depression
9642117 Negative gene expression regulation by 'Mecp2:Crh gene [nucleoplasm]' Enhanced anxiety and stress-induced corticosterone release are associated with increased Crh expression in a mouse model of Rett syndrome
9642753 Negative gene expression regulation by 'Mecp2:Dll1 gene [nucleoplasm]' Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway
9642211 Negative gene expression regulation by 'Mecp2:Fkbp5 gene [nucleoplasm]' Mecp2-null mice provide new neuronal targets for Rett syndrome
9642147 Negative gene expression regulation by 'Mecp2:Grin2b gene [nucleoplasm]' Activity-dependent NR2B expression is mediated by MeCP2-dependent epigenetic regulation
9642568 Negative gene expression regulation by 'Mecp2:Mef2c gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
9641931 Negative gene expression regulation by 'Mecp2:Mobp gene [nucleoplasm]' Mecp2-null mice provide new neuronal targets for Rett syndrome
9641866 Negative gene expression regulation by 'Mecp2:Notch1 gene [nucleoplasm]' Cell cycle-linked MeCP2 phosphorylation modulates adult neurogenesis involving the Notch signalling pathway
9641246 Negative gene expression regulation by 'Mecp2:Pparg gene [nucleoplasm]' MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis