RB1 L158Mfs*19 [cytosol]

Stable Identifier
R-HSA-9688141
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
RB1 L158Mfs*19 [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
RB1
Chain
initiator methionine:, chain:2-928
Reference Transcript
Other Identifiers
11717702_a_at
11749112_a_at
11753684_a_at
1571_f_at
1672_f_at
16774690
1900_at
1905_s_at
203132_PM_at
203132_at
2044_s_at
211540_PM_s_at
211540_s_at
3489023
3489024
3489026
3489035
3489036
3489037
3489038
3489039
3489042
3489043
3489044
3489045
3489046
3489050
3489052
3489054
3489057
3489058
3489059
3489060
3489061
3489079
3489080
3489081
3489082
3489083
3489085
3489086
3489090
3489091
3489092
3489093
3489094
3489095
3489098
3489099
3489100
3489101
3489108
5925
7969017
A_14_P110907
A_14_P139049
A_23_P204850
A_24_P102636
GE57770
GE85157
GO:0000082
GO:0000122
GO:0000785
GO:0000977
GO:0001558
GO:0001894
GO:0002062
GO:0003180
GO:0003674
GO:0003677
GO:0003714
GO:0005515
GO:0005575
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0005819
GO:0005829
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006469
GO:0006915
GO:0007224
GO:0007265
GO:0007283
GO:0007346
GO:0008024
GO:0008150
GO:0008283
GO:0008285
GO:0010629
GO:0012501
GO:0014009
GO:0016514
GO:0016605
GO:0019899
GO:0019900
GO:0022414
GO:0030154
GO:0030182
GO:0030308
GO:0031134
GO:0031175
GO:0031507
GO:0031625
GO:0032869
GO:0034088
GO:0034349
GO:0035189
GO:0035914
GO:0042551
GO:0042802
GO:0043226
GO:0043353
GO:0043433
GO:0043550
GO:0045445
GO:0045651
GO:0045786
GO:0045842
GO:0045879
GO:0045892
GO:0045930
GO:0045944
GO:0048565
GO:0048667
GO:0048856
GO:0050673
GO:0050680
GO:0050728
GO:0051146
GO:0051219
GO:0051276
GO:0051301
GO:0051402
GO:0051726
GO:0060090
GO:0060253
GO:0060255
GO:0061629
GO:0061676
GO:0061793
GO:0071459
GO:0071466
GO:0071901
GO:0080090
GO:0090230
GO:0097284
GO:0097718
GO:0120163
GO:0140110
GO:0140297
GO:1902948
GO:1903055
GO:1903944
GO:1904028
GO:1904761
GO:2000045
GO:2000134
GO:2000679
GO:2001234
HMNXSV003035055
ILMN_1696591
L41870_at
L49209_s_at
L49218_f_at
L49229_f_at
PH_hs_0024754
TC13000190.hg
g190967_3p_a_at
g4506434_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Replacement of residues 158 to 175 by MYCLHSSANWKGHVNLYI
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
head and neck squamous cell carcinoma DOID:5520 carcinoma of the head and neck, squamous cell carcinoma of the head and neck
Cross References
RefSeq
OpenTargets
ZINC - Substances
ZINC target
PRO
GlyGen
COSMIC
Pharos - Targets
Orphanet
RB1
ZINC - Predictions - Purchasable
Interactors (65)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q01094 E2F1  2 0.97 30
 UniProt:P03129 VE7      0.969 28
 UniProt:Q13547 HDAC1  2 0.955 18
 UniProt:P03070 LT      0.927 9
 UniProt:P03255 E1A      0.921 10
 UniProt:O00716 E2F3  2 0.822 5
 UniProt:Q14209 E2F2  1 0.78 5
 UniProt:P06788 VE7      0.772 4
 UniProt:P62136 PPP1CA  1 0.771 5
 UniProt:Q16254 E2F4  1 0.757 6
 UniProt:Q14188 TFDP2  1 0.744 5
 UniProt:Q14186 TFDP1  1 0.744 6
 UniProt:Q00987 MDM2  11 0.734 5
 UniProt:P24385 CCND1  4 0.73 5
 UniProt:P04020 VE7      0.702 3
 UniProt:P03255-2      0.702 3
 UniProt:P06464 VE7      0.688 3
 UniProt:Q9Y463 DYR1B      0.67 4
 UniProt:Q13627 DYRK1A  1 0.67 4
 UniProt:P06400 RB1  20 0.667 3
 UniProt:P06465 VE7      0.647 3
 UniProt:Q13363 CTBP1  3 0.643 3
 UniProt:P52927  1 0.632 5
 UniProt:P30285 Cdk4  6 0.623 2
 UniProt:Q16539 MAPK14  7 0.623 4
 UniProt:P24941 CDK2  5 0.623 3
 UniProt:P39880 CUX1  2 0.611 4
 UniProt:P62993 GRB2  1 0.61 4
 UniProt:Q15329 E2F5  1 0.609 2
 UniProt:Q923E4 Sirt1  2 0.602 4
 UniProt:O96017 CHEK2  3 0.602 3
 UniProt:Q14686 NCOA6  1 0.593 3
 UniProt:Q96PU4 UHRF2  1 0.591 4
 UniProt:Q13574-2 DGKZ      0.591 6
 UniProt:P03255-1      0.589 2
 UniProt:Q3TKT4 Smarca4  2 0.573 4
 UniProt:Q93009 USP7  2 0.571 8
 UniProt:Q99708 RBBP8  4 0.564 2
 UniProt:P03254 E1A      0.558 3
 UniProt:O14757 CHEK1  3 0.558 3
 UniProt:P0C6X7-PRO_0000037321 REP      0.556 3
 UniProt:Q8VSP9 OSPF      0.544 2
 IntAct:EBI-971875 DGKZ-MARCKS-PSD      0.544 2
 UniProt:P55345 ANM2      0.544 3
 UniProt:Q9R002 IFI2      0.544 5
 UniProt:P42685 FRK  4 0.544 3
 UniProt:Q6ZUJ4 CC062      0.527 2
 UniProt:Q5H9I0 TFDP3      0.527 3
 UniProt:Q9NQ55 SSF1      0.527 2
 UniProt:P04637 TP53  20 0.527 2
 UniProt:P40937 RFC5  1 0.527 2
 UniProt:Q9Y676 MRPS18B  1 0.525 2
 UniProt:O15151 MDM4  5 0.524 4
 UniProt:Q86500-PRO_0000041225      0.524 3
 UniProt:A0MPS7 A0MPS7      0.524 2
 UniProt:P07197 NFM      0.524 2
 UniProt:Q9UQ80 PA2G4  2 0.524 4
 UniProt:Q00577 PURA      0.524 6
 UniProt:P24863 CCNC  1 0.524 4
 UniProt:O75150 RNF40  1 0.508 3
 UniProt:P29375 KDM5A  1 0.499 2
 UniProt:Q14653 IRF3  6 0.499 2
 UniProt:O43524 FOXO3  11 0.499 2
 UniProt:Q9UKV8 AGO2  2 0.499 3
 UniProt:Q5R372-2 RABGAP1L      0.488 2
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