CUX1-FGFR1 fusion [cytosol]

Stable Identifier
R-HSA-1614371
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
CUX1(1-339)-FGFR1(429-822) fusion, t(7;8) CUX1-FGFR1 fusion
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
21330321 The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with T-lymphoblastic leukemia/lymphoma and t(7;8)(q22;p11)

Wasag, B, Lierman, E, Meeus, P, Cools, J, Vandenberghe, P

Haematologica 2011
External Reference Information
External Reference
Gene Names
CUX1, CUTL1
Chain
chain:1-1505
Other Identifiers
0001690014
0002260019
11717338_a_at
11732370_a_at
11749496_a_at
11751749_a_at
1523
17049729
202367_at
214743_at
225935_at
225937_at
227069_at
3003473
3016381
3016382
3016384
3016385
3016400
3016414
3016423
3016431
3016433
3016436
3016438
3016455
3016460
3016462
3016465
3016467
3016469
3016471
3016472
3016473
3016474
3016475
3016476
3016477
3016478
3016479
3016492
3016493
3016494
3016496
3016498
3016499
3016500
3016501
3016502
3016503
3016504
3016505
3016506
3016507
3016508
3016510
3016511
3016512
3016513
3016514
3016516
3016518
3016520
3016521
3016522
3016523
3016625
3016627
3016628
3016629
3016630
3016631
3016632
3016634
3052946
31822_at
31823_at
48445_at
54869_at
8135114
87296_at
90590_at
A_14_P123491
A_23_P253375
A_24_P220454
A_24_P691604
A_33_P3298785
GE56961
GE56987
GE58066
GE62532
GO:0000122
GO:0000139
GO:0000228
GO:0000301
GO:0000790
GO:0000902
GO:0000977
GO:0000981
GO:0003674
GO:0003677
GO:0003700
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005794
GO:0005829
GO:0006355
GO:0006357
GO:0006810
GO:0006891
GO:0007275
GO:0008150
GO:0009058
GO:0016192
GO:0030154
GO:0030173
GO:0030674
GO:0034641
GO:0043226
GO:0043565
GO:0048193
GO:0048856
GO:0050775
GO:1990837
Hs.147049.1.S1_3p_at
Hs.19215.0.A1_3p_at
Hs.19215.0.A2_3p_at
Hs.77273.2.A1_3p_at
ILMN_1687567
ILMN_1744659
ILMN_2278636
ILMN_2330213
M74099_at
PH_hs_0016862
PH_hs_0025715
TC07002501.hg
g4503168_3p_at
Participant Of
Other forms of this molecule
Modified Residues
Name
Insertion of residues 429 to 822 at 340 from UniProt:P11362 FGFR1
Coordinate
340
Disease
Name Identifier Synonyms
precursor lymphoblastic lymphoma/leukemia 5600
subacute leukemia 3264
myelodysplastic myeloproliferative cancer 4972 Myeloproliferative/Myelodysplastic syndromes, unclassifiable myelodysplastic myeloproliferative disease, Unclassifiable Myeloproliferative/Myelodysplastic syndrome, Myelodysplastic/myeloproliferative disease (morphologic abnormality)
Interactors (1)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P06400 RB1  394 0.611 4
Cite Us!