Reactome | MRPS18B [mitochondrial inner membrane]

MRPS18B [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368234

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

28S ribosomal protein S18b, mitochondrial, RT18B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y676 MRPS18B

Gene Names

MRPS18B, C6orf14, HSPC183, PTD017

Chain

transit peptide:1-35, chain:36-258

Reference Genes

BioGPS Gene:28973 MRPS18B

COSMIC (genes):MRPS18B MRPS18B

CTD Gene:28973 MRPS18B

dbSNP Gene:28973 MRPS18B

ENSEMBL:ENSG00000204568 MRPS18B

HGNC:14516 MRPS18B

KEGG:hsa:28973 MRPS18B

Monarch:28973 MRPS18B

NCBI Gene:28973 MRPS18B

OMIM:611982 MRPS18B

UCSC:Q9Y676 MRPS18B

Reference Transcript

RefSeq:NM_014046.3 MRPS18B

Other Identifiers

11746187_x_at

11754356_x_at

17006324

17027506

17030351

17033056

17035176

17037835

17040549

208907_PM_s_at

208907_s_at

217408_PM_at

217408_at

28973

2901824

2901825

2901826

2901827

2901828

2901829

2901830

2901831

2901832

2901834

2901836

2901837

2901838

2901839

2901840

2901842

2901843

2901844

2901845

2901846

2901847

2901848

32221_at

8117955

8177824

8179139

A_14_P101539

A_14_P132249

A_23_P59107

A_33_P3336992

GE61838

GO:0003735

GO:0005198

GO:0005515

GO:0005654

GO:0005739

GO:0005743

GO:0005763

GO:0005840

GO:0006412

GO:0030054

GO:0032543

GO:0043226

GO:1990904

HMNXSV003036402

Hs.274417.2.S1_3p_at

ILMN_1721337

ILMN_2121282

PH_hs_0014163

PH_hs_0032419

TC06000343.hg

TC6_cox_hap2000041.hg

TC6_dbb_hap3000034.hg

TC6_mann_hap4000036.hg

TC6_mcf_hap5000028.hg

TC6_qbl_hap6000034.hg

TC6_ssto_hap7000034.hg

g13529220_3p_a_at

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)

Inferred To

mrps-18b [mitochondrial inner membrane] (Caenorhabditis elegans)

mRpS18B [mitochondrial inner membrane] (Drosophila melanogaster)

mrps18b [mitochondrial inner membrane] (Danio rerio)

MRPS18B [mitochondrial inner membrane] (Bos taurus)

MRPS18B [mitochondrial inner membrane] (Canis familiaris)

MRPS18B [mitochondrial inner membrane] (Sus scrofa)

Mrps18b [mitochondrial inner membrane] (Mus musculus)

Mrps18b [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000204568

ENSEMBL

ENSP00000259873, ENST00000412451, ENST00000426945, ENST00000259873, ENST00000454427, ENST00000451032, ENST00000327800, ENSP00000397790, ENSP00000415703, ENSP00000383438, ENST00000430402, ENSP00000398494, ENSP00000414972, ENSP00000402718

HPA

ENSG00000204568-MRPS18B

PRO

Q9Y676

Pharos - Targets

Q9Y676

GlyGen

Q9Y676

PDB

7A5G, 7A5I, 6RW5, 7A5F, 6NU3, 8ANY, 6NU2, 6RW4, 7QI6, 7P2E, 7PO3, 7OG4, 7PNZ, 8CSU, 7QI4, 6ZSE, 6VLZ, 7L08, 6ZSD, 6ZSC, 6ZM5, 6ZM6, 7PO2, 8CST, 7QI5, 7PO1, 7PNY, 6VMI, 6ZSA, 6ZS9, 6ZSB, 7PNX, 3J9M, 6ZSG, 8OIS, 8CSQ, 7PO0, 7A5K, 8CSS, 8OIR, 8CSP, 8CSR

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62753 RPS6	4	RPS6 [cytosol] (R-HSA-72381) p-5S-RPS6 [cytosol] (R-HSA-165727) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) RPS6 [nucleoplasm] (R-HSA-6790606)	0.569	3
UniProt:O43561-2 LAT	2	p-5Y-LAT-2 [plasma membrane] (R-HSA-2396597) LAT-2 [plasma membrane] (R-HSA-2396548)	0.556	3
UniProt:P78382 SLC35A1	2	SLC35A1 [Golgi membrane] (R-HSA-727812) SLC35A1 V93Cfs*17 [Golgi membrane] (R-HSA-5651957)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:P24593 IGFBP5	5	IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956738) p-IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956988) IGFBP5 [extracellular region] (R-HSA-381414) IGFBP5(21-163) [extracellular region] (R-HSA-381415) IGFBP5(164-272) [extracellular region] (R-HSA-381478)	0.556	3
UniProt:Q8N2H4 SYS1	1	SYS1 [trans-Golgi network membrane] (R-HSA-6813921)	0.556	3
UniProt:P06400 RB1	20	RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288)	0.525	2
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.483	2

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