Reactome | PA2G4 [extracellular region]

PA2G4 [extracellular region]

Stable Identifier

R-HSA-6806200

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

EBP1 (PA2G4), Proliferation-associated protein 2G4, PA2G4_HUMAN, EBP1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UQ80 PA2G4

Gene Names

PA2G4, EBP1

Chain

initiator methionine:1, chain:2-394

Reference Genes

BioGPS Gene:5036 PA2G4

COSMIC (genes):PA2G4 PA2G4

CTD Gene:5036 PA2G4

dbSNP Gene:5036 PA2G4

ENSEMBL:ENSG00000170515 PA2G4

ENSEMBL:ENSG00000170515.14 PA2G4

HGNC:8550 PA2G4

KEGG Gene (Homo sapiens):5036 PA2G4

Monarch:5036 PA2G4

NCBI Gene:5036 PA2G4

OMIM:602145 PA2G4

UCSC:Q9UQ80 PA2G4

Reference Transcript

RefSeq:NM_006191.2 PA2G4

Other Identifiers

11723412_s_at

11757850_s_at

208676_PM_s_at

208676_s_at

214794_PM_at

214794_at

2970336

3170522

3417310

3417311

3417312

3417313

3417318

3417319

3417321

3417323

3417324

3417326

3417327

3417329

3417331

3417333

3417335

3417336

3417337

3417338

3417339

3417340

3417341

3417342

3876803

4020072

41600_at

5036

7956152

80456_s_at

A_23_P116679

A_32_P11181

A_33_P3227209

GE61650

GO:0003676

GO:0003714

GO:0003723

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005730

GO:0005737

GO:0005764

GO:0005773

GO:0006351

GO:0006355

GO:0006364

GO:0006417

GO:0012501

GO:0016020

GO:0030154

GO:0031410

GO:0031625

GO:0035578

GO:0042254

GO:0043066

GO:0043226

GO:0045597

GO:0045892

GO:0070062

GO:0140110

GO:1990904

HMNXSV003044766

Hs.5181.2.S1_3p_at

Hs.5181.2.S1_3p_x_at

ILMN_1728984

PH_hs_0018140

TC12003244.hg

g4099505_3p_a_at

Participates

as a member of

Azurophil granule lumen proteins [extracellular region] (Homo sapiens)

Other forms of this molecule

PA2G4 [azurophil granule lumen]

Inferred To

ARX1 [extracellular region] (Saccharomyces cerevisiae)

BEST:CK00496 [extracellular region] (Drosophila melanogaster)

cdb4 [extracellular region] (Schizosaccharomyces pombe)

Pa2g4 [extracellular region] (Mus musculus)

Pa2g4 [extracellular region] (Rattus norvegicus)

pa2g4 [extracellular region] (Danio rerio)

pa2g4 [extracellular region] (Xenopus tropicalis)

prlA [extracellular region] (Dictyostelium discoideum)

PA2G4 [extracellular region] (Bos taurus)

PA2G4 [extracellular region] (Caenorhabditis elegans)

PA2G4 [extracellular region] (Canis familiaris)

PA2G4 [extracellular region] (Gallus gallus)

PA2G4 [extracellular region] (Plasmodium falciparum)

PA2G4 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_006182.2

OpenTargets

ENSG00000170515

HPA

ENSG00000170515-PA2G4

GeneCards

Q9UQ80

Ensembl

ENSP00000302886, ENSG00000170515, ENST00000303305

PRO

Q9UQ80

Pharos - Targets

Q9UQ80

PDB

6Z6L, 6ZME, 3J2I, 6ZMO, 6CHT, 6ZMI, 6WM8, 6LSR, 6Z6N, 6Z6M, 6SXO, 6ZM7, 2Q8K, 7BHP

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96ST3 SIN3A	2	SIN3A [nucleoplasm] (R-HSA-351657) monoSUMO1-SIN3A [nucleoplasm] (R-HSA-4086071)	0.602	4
UniProt:P62917 RPL8	3	3OHH216-RPL8 [nucleoplasm] (R-HSA-9630976) RPL8 [nucleoplasm] (R-HSA-9630985) RPL8 [cytosol] (R-HSA-72490)	0.528	2
UniProt:P06400 RB1	20	RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288)	0.524	4
UniProt:P19338 NCL	1	NCL [nucleoplasm] (R-HSA-6791213)	0.499	2
UniProt:P06748 NPM1	11	monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1 [granular component] (R-HSA-9017702) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679)	0.491	3

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