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RB1 A635Gfs*6 [cytosol]
Stable Identifier
R-HSA-9688024
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of mitotic cell cycle (Homo sapiens)
Aberrant regulation of mitotic cell cycle due to RB1 defects (Homo sapiens)
Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects (Homo sapiens)
Defective translocation of RB1 mutants to the nucleus (Homo sapiens)
Defective RB1 does not translocate to the nucleus (Homo sapiens)
RB1 mutants (localization) [cytosol] (Homo sapiens)
RB1 A635Gfs*6 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P06400 RB1
Gene Names
RB1
Chain
initiator methionine:, chain:2-928
Reference Genes
BioGPS Gene:5925 RB1
COSMIC (genes):RB1 RB1
CTD Gene:5925 RB1
dbSNP Gene:5925 RB1
ENSEMBL:ENSG00000139687 RB1
ENSEMBL_homo_sapiens_GENE:ENSG00000139687.16 RB1
HGNC:9884 RB1
KEGG Gene (Homo sapiens):5925 RB1
Monarch:5925 RB1
NCBI Gene:5925 RB1
OMIM:614041 RB1
UCSC:P06400 RB1
Reference Transcript
RefSeq:NM_000321.2 RB1
Other Identifiers
11717702_a_at
11749112_a_at
11753684_a_at
1571_f_at
1672_f_at
16774690
1900_at
1905_s_at
203132_PM_at
203132_at
2044_s_at
211540_PM_s_at
211540_s_at
3489023
3489024
3489026
3489036
3489037
3489038
3489039
3489042
3489043
3489045
3489046
3489050
3489052
3489054
3489057
3489058
3489059
3489060
3489061
3489080
3489081
3489082
3489083
3489085
3489086
3489090
3489094
3489095
3489098
3489099
3489100
5925
7969017
A_14_P110907
A_14_P139049
A_23_P204850
GE57770
GO:0000082
GO:0000122
GO:0000278
GO:0000785
GO:0000977
GO:0001558
GO:0001894
GO:0002062
GO:0002376
GO:0003180
GO:0003677
GO:0003714
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005819
GO:0005829
GO:0005856
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006469
GO:0006915
GO:0006954
GO:0007049
GO:0007059
GO:0007224
GO:0007265
GO:0007283
GO:0007346
GO:0008024
GO:0008283
GO:0008285
GO:0010629
GO:0012501
GO:0014009
GO:0016514
GO:0016605
GO:0019899
GO:0019900
GO:0022414
GO:0023052
GO:0030154
GO:0030182
GO:0030198
GO:0030308
GO:0031134
GO:0031175
GO:0031507
GO:0031625
GO:0032869
GO:0034088
GO:0034349
GO:0035189
GO:0035914
GO:0036211
GO:0042551
GO:0042802
GO:0043226
GO:0043353
GO:0043433
GO:0043550
GO:0045445
GO:0045651
GO:0045786
GO:0045842
GO:0045879
GO:0045892
GO:0045930
GO:0045944
GO:0048565
GO:0048667
GO:0048856
GO:0050673
GO:0050680
GO:0050728
GO:0051146
GO:0051172
GO:0051219
GO:0051276
GO:0051301
GO:0051402
GO:0051726
GO:0060090
GO:0060253
GO:0060255
GO:0061629
GO:0061676
GO:0061793
GO:0065003
GO:0071459
GO:0071466
GO:0071901
GO:0080090
GO:0090230
GO:0097284
GO:0097718
GO:0120163
GO:0140014
GO:0140110
GO:0140297
GO:1902948
GO:1903055
GO:1903944
GO:1904028
GO:1904761
GO:2000045
GO:2000134
GO:2000679
GO:2001234
HMNXSV003035055
ILMN_1696591
L41870_at
L49209_s_at
L49218_f_at
L49229_f_at
PH_hs_0024754
TC13000190.hg
g190967_3p_a_at
g4506434_3p_at
Participates
as a candidate of
RB1 mutants (localization) [cytosol] (Homo sapiens)
Other forms of this molecule
RB1 R661W [nucleoplasm]
RB1 C706F [nucleoplasm]
RB1 N480del [nucleoplasm]
RB1 C706Y [nucleoplasm]
RB1 R661Q [nucleoplasm]
RB1 I703_E737del [nucleoplasm]
RB1 R830_G887del [cytosol]
RB1 K791* [cytosol]
RB1 Q176* [cytosol]
RB1 S114* [cytosol]
RB1 K765* [cytosol]
RB1 W99* [cytosol]
RB1 S149* [cytosol]
RB1 E166* [cytosol]
RB1 G100* [cytosol]
RB1 E125* [cytosol]
RB1 Q121* [cytosol]
RB1 E184* [cytosol]
RB1 E137* [cytosol]
RB1 K745* [cytosol]
RB1 E209* [cytosol]
RB1 S618* [cytosol]
RB1 S463* [cytosol]
RB1 K720* [cytosol]
RB1 K429* [cytosol]
RB1 K652* [cytosol]
RB1 K715* [cytosol]
RB1 K615* [cytosol]
RB1 K412* [cytosol]
RB1 S567* [cytosol]
RB1 S807* [cytosol]
RB1 R467* [cytosol]
RB1 S834* [cytosol]
RB1 S576* [cytosol]
RB1 S758* [cytosol]
RB1 R7Pfs*24 [cytosol]
RB1 S443* [cytosol]
RB1 S648* [cytosol]
RB1 S391* [cytosol]
RB1 S829* [cytosol]
RB1 D32Tfs*33 [cytosol]
RB1 Y651Ifs*7 [cytosol]
RB1 K143Mfs*19 [cytosol]
RB1 V754Sfs*4 [cytosol]
RB1 L44Rfs*4 [cytosol]
RB1 E97Gfs*13 [cytosol]
RB1 I679* [cytosol]
RB1 W195* [cytosol]
RB1 G100Efs*11 [cytosol]
RB1 S648Tfs*4 [cytosol]
RB1 H281Qfs*6 [cytosol]
RB1 Q384* [cytosol]
RB1 S182Yfs*2 [cytosol]
RB1 L343Sfs*3 [cytosol]
RB1 L337Wfs*12 [cytosol]
RB1 S318* [cytosol]
RB1 N627Mfs*16 [cytosol]
RB1 N290Kfs*20 [cytosol]
RB1 F299Lfs*4 [cytosol]
RB1 Q637* [cytosol]
RB1 L76* [cytosol]
RB1 Q762* [cytosol]
RB1 Y655Lfs*4 [cytosol]
RB1 N480Kfs*13 [cytosol]
RB1 Q444* [cytosol]
RB1 T77Lfs*34 [cytosol]
RB1 E747Gfs*3 [cytosol]
RB1 M825* [cytosol]
RB1 L649Ffs*11 [cytosol]
RB1 N472Ifs*6 [cytosol]
RB1 Y813Kfs*12 [cytosol]
RB1 I324Mfs*17 [cytosol]
RB1 M460Ifs*3 [cytosol]
RB1 Y655Ifs*3 [cytosol]
RB1 L769Cfs*41 [cytosol]
RB1 P28Lfs*37 [cytosol]
RB1 E677Dfs*19 [cytosol]
RB1 P370Lfs*10 [cytosol]
RB1 N593Tfs*11 [cytosol]
RB1 K329* [cytosol]
RB1 S249Ffs*22 [cytosol]
RB1 K240* [cytosol]
RB1 L199Ffs*4 [cytosol]
RB1 P253Gfs*5 [cytosol]
RB1 K289* [cytosol]
RB1 S360Pfs*2 [cytosol]
RB1 E323Kfs*9 [cytosol]
RB1 L326* [cytosol]
RB1 P808Kfs*12 [cytosol]
RB1 D584Nfs*2 [cytosol]
RB1 N406Kfs*4 [cytosol]
RB1 K417Wfs*23 [cytosol]
RB1 L797Ffs*18 [cytosol]
RB1 Q266Hfs*2 [cytosol]
RB1 R255* [cytosol]
RB1 K4* [cytosol]
RB1 P641Afs*12 [cytosol]
RB1 V450Sfs*13 [cytosol]
RB1 K524Rfs*28 [cytosol]
RB1 E280* [cytosol]
RB1 M825Ifs*13 [cytosol]
RB1 M761Nfs*21 [cytosol]
RB1 A11Rfs*20 [cytosol]
RB1 E275* [cytosol]
RB1 Q266* [cytosol]
RB1 I66Yfs*11 [cytosol]
RB1 Q257* [cytosol]
RB1 P39Rfs*26 [cytosol]
RB1 T664Nfs*4 [cytosol]
RB1 Y771Lfs*24 [cytosol]
RB1 R320Dfs*12 [cytosol]
RB1 E282* [cytosol]
RB1 L277Pfs*9 [cytosol]
RB1 I124* [cytosol]
RB1 N803Tfs*7 [cytosol]
RB1 M386Ifs*11 [cytosol]
RB1 E72Vfs*34 [cytosol]
RB1 R150Kfs*7 [cytosol]
RB1 L743* [cytosol]
RB1 R7Efs*58 [cytosol]
RB1 T140Nfs*6 [cytosol]
RB1 D479Efs*16 [cytosol]
RB1 L199* [cytosol]
RB1 G801* [cytosol]
RB1 S215* [cytosol]
RB1 G435* [cytosol]
RB1 G581* [cytosol]
RB1 L134* [cytosol]
RB1 Y529Lfs*26 [cytosol]
RB1 S816Qfs*10 [cytosol]
RB1 E693Nfs*3 [cytosol]
RB1 D346Rfs*4 [cytosol]
RB1 Q35* [cytosol]
RB1 I806Lfs*10 [cytosol]
RB1 E54* [cytosol]
RB1 L199Yfs*2 [cytosol]
RB1 E48* [cytosol]
RB1 N854* [cytosol]
RB1 W75* [cytosol]
RB1 L389Ffs*3 [cytosol]
RB1 S230* [cytosol]
RB1 H483Sfs*10 [cytosol]
RB1 S842* [cytosol]
RB1 W78* [cytosol]
RB1 G449Efs*8 [cytosol]
RB1 K63* [cytosol]
RB1 K537Nfs*14 [cytosol]
RB1 L206* [cytosol]
RB1 K63Rfs*38 [cytosol]
RB1 P732Lfs*12 [cytosol]
RB1 L158* [cytosol]
RB1 A562Hfs*49 [cytosol]
RB1 E72* [cytosol]
RB1 G540Afs*3 [cytosol]
RB1 N328Ifs*4 [cytosol]
RB1 E843* [cytosol]
RB1 L385* [cytosol]
RB1 E464* [cytosol]
RB1 N123Tfs*2 [cytosol]
RB1 E112Dfs*6 [cytosol]
RB1 E748* [cytosol]
RB1 M148Ifs*8 [cytosol]
RB1 R661* [cytosol]
RB1 Y453* [cytosol]
RB1 K95* [cytosol]
RB1 M484Vfs*8 [cytosol]
RB1 E533* [cytosol]
RB1 G86* [cytosol]
RB1 V654Sfs*14 [cytosol]
RB1 E747* [cytosol]
RB1 E79* [cytosol]
RB1 C553Wfs*53 [cytosol]
RB1 E677* [cytosol]
RB1 K96* [cytosol]
RB1 C102Yfs*7 [cytosol]
RB1 E737* [cytosol]
RB1 E97* [cytosol]
RB1 R579Qfs*29 [cytosol]
RB1 A525Pfs*7 [cytosol]
RB1 L542Kfs*11 [cytosol]
RB1 F482Sfs*10 [cytosol]
RB1 L797* [cytosol]
RB1 P250Afs*16 [cytosol]
RB1 S194Ffs*7 [cytosol]
RB1 N623Qfs*15 [cytosol]
RB1 T9Rfs*56 [cytosol]
RB1 Y813Qfs*10 [cytosol]
RB1 I768Cfs*23 [cytosol]
RB1 L477Mfs*17 [cytosol]
RB1 E675* [cytosol]
RB1 V654Cfs*4 [cytosol]
RB1 F650Lfs*5 [cytosol]
RB1 P39Sfs*10 [cytosol]
RB1 H281Sfs*2 [cytosol]
RB1 E551* [cytosol]
RB1 C61Vfs*4 [cytosol]
RB1 D145Ifs*8 [cytosol]
RB1 M148Hfs*9 [cytosol]
RB1 E837* [cytosol]
RB1 L158Mfs*19 [cytosol]
RB1 L832Ffs*5 [cytosol]
RB1 E440* [cytosol]
RB1 D224Afs*40 [cytosol]
RB1 P822Qfs*4 [cytosol]
RB1 M148Vfs*8 [cytosol]
RB1 L670Cfs*7 [cytosol]
RB1 E465* [cytosol]
RB1 S414Kfs*14 [cytosol]
RB1 K548Nfs*3 [cytosol]
RB1 L135Tfs*5 [cytosol]
RB1 Q207Tfs*5 [cytosol]
RB1 Q384Tfs*11 [cytosol]
RB1 L797Ffs*14 [cytosol]
RB1 P232Rfs*4 [cytosol]
RB1 T497Hfs*22 [cytosol]
RB1 E817* [cytosol]
RB1 N367* [cytosol]
RB1 L809Rfs*17 [cytosol]
RB1 E693* [cytosol]
RB1 K80* [cytosol]
RB1 W99Lfs*11 [cytosol]
RB1 A15Pfs*3 [cytosol]
RB1 Y239Lfs*25 [cytosol]
RB1 D571Lfs*41 [cytosol]
RB1 N186Ifs*6 [cytosol]
RB1 E837Dfs*12 [cytosol]
RB1 E672* [cytosol]
RB1 H483Yfs*9 [cytosol]
RB1 R775Gfs*35 [cytosol]
RB1 E580* [cytosol]
RB1 G617Rfs*36 [cytosol]
RB1 E492* [cytosol]
RB1 A333Ffs*13 [cytosol]
RB1 L564Sfs*47 [cytosol]
RB1 D156Vfs*19 [cytosol]
RB1 C438Vfs*19 [cytosol]
RB1 C278* [cytosol]
RB1 E209Vfs*3 [cytosol]
RB1 T116Lfs*8 [cytosol]
RB1 R698Afs*22 [cytosol]
RB1 V419* [cytosol]
RB1 I415Nfs*13 [cytosol]
RB1 Y173Ffs*11 [cytosol]
RB1 N133Tfs*3 [cytosol]
RB1 M695Rfs*10 [cytosol]
RB1 R418Sfs*9 [cytosol]
RB1 Q689* [cytosol]
RB1 A74Efs*4 [cytosol]
RB1 W99Yfs*5 [cytosol]
RB1 G442Dfs*15 [cytosol]
RB1 N258Efs*11 [cytosol]
RB1 S182Ifs*3 [cytosol]
RB1 Q436* [cytosol]
RB1 Q395Pfs*11 [cytosol]
RB1 Y606Lfs*47 [cytosol]
RB1 E539* [cytosol]
RB1 L317* [cytosol]
RB1 F104Lfs*7 [cytosol]
RB1 E691* [cytosol]
RB1 D340Yfs*5 [cytosol]
RB1 K740Tfs*10 [cytosol]
RB1 H483Ifs*12 [cytosol]
RB1 R611Lfs*43 [cytosol]
RB1 V291Ifs*9 [cytosol]
RB1 N133* [cytosol]
RB1 R334* [cytosol]
RB1 D697Qfs*23 [cytosol]
RB1 L647Ffs*5 [cytosol]
RB1 I723Nfs*28 [cytosol]
RB1 L486Ifs*6 [cytosol]
RB1 S565* [cytosol]
RB1 Y529Tfs*3 [cytosol]
RB1 Q631* [cytosol]
RB1 S318Nfs*13 [cytosol]
RB1 D856Efs*17 [cytosol]
RB1 P595Lfs*16 [cytosol]
RB1 P777Lfs*33 [cytosol]
RB1 G310Dfs*22 [cytosol]
RB1 P250Sfs*20 [cytosol]
RB1 Q850* [cytosol]
RB1 I124Rfs*6 [cytosol]
RB1 Q702* [cytosol]
RB1 E748Dfs*6 [cytosol]
RB1 Q736* [cytosol]
RB1 R798Qfs*4 [cytosol]
RB1 S588Ffs*6 [cytosol]
RB1 K574* [cytosol]
RB1 D156Mfs*19 [cytosol]
RB1 Y771Cfs*23 [cytosol]
RB1 I66Dfs*44 [cytosol]
RB1 Q685* [cytosol]
RB1 E125Kfs*11 [cytosol]
RB1 Y655Lfs*13 [cytosol]
RB1 R828Kfs*10 [cytosol]
RB1 Y659Ifs*4 [cytosol]
RB1 Q846* [cytosol]
RB1 E97Nfs*14 [cytosol]
RB1 Q770* [cytosol]
RB1 C666* [cytosol]
RB1 Q471* [cytosol]
RB1 R71Efs*39 [cytosol]
RB1 Q504* [cytosol]
RB1 R798Tfs*17 [cytosol]
RB1 Q639* [cytosol]
RB1 N328* [cytosol]
RB1 S576Rfs*34 [cytosol]
RB1 T726Nfs*25 [cytosol]
RB1 Q597* [cytosol]
RB1 I532Nfs*57 [cytosol]
RB1 K577Rfs*34 [cytosol]
RB1 R73Sfs*36 [cytosol]
RB1 E413Kfs*4 [cytosol]
RB1 K844Sfs*5 [cytosol]
RB1 A17Pfs*3 [cytosol]
RB1 Q395* [cytosol]
RB1 L523* [cytosol]
RB1 R251* [cytosol]
RB1 L389* [cytosol]
RB1 Q217* [cytosol]
RB1 Q344* [cytosol]
RB1 S634* [cytosol]
RB1 S397* [cytosol]
RB1 S838* [cytosol]
RB1 R556* [cytosol]
RB1 R787* [cytosol]
RB1 G304* [cytosol]
RB1 W516* [cytosol]
RB1 W681* [cytosol]
RB1 E322* [cytosol]
RB1 W563* [cytosol]
RB1 L550* [cytosol]
RB1 R552* [cytosol]
RB1 L512* [cytosol]
RB1 R455* [cytosol]
RB1 R763* [cytosol]
RB1 L779* [cytosol]
RB1 R445* [cytosol]
RB1 R544* [cytosol]
RB1 R320* [cytosol]
RB1 L832* [cytosol]
RB1 Y498* [cytosol]
RB1 Y446* [cytosol]
RB1 Y655* [cytosol]
RB1 E323* [cytosol]
RB1 E364* [cytosol]
RB1 C489* [cytosol]
RB1 G310* [cytosol]
RB1 L335* [cytosol]
RB1 E313* [cytosol]
RB1 E315* [cytosol]
RB1 D479Vfs*14 [cytosol]
RB1 C489Lfs*5 [cytosol]
RB1 Y454* [cytosol]
RB1 E137Rfs*3 [cytosol]
RB1 L676Ffs*16 [cytosol]
RB1 Y728* [cytosol]
RB1 I799Ffs*11 [cytosol]
RB1 D346Vfs*17 [cytosol]
RB1 F514Pfs*8 [cytosol]
RB1 N593Sfs*5 [cytosol]
RB1 T58Yfs*52 [cytosol]
RB1 N522Ifs*2 [cytosol]
RB1 C553Vfs*58 [cytosol]
RB1 P609Cfs*43 [cytosol]
RB1 N269* [cytosol]
RB1 E287Rfs*2 [cytosol]
RB1 E492Lfs*4 [cytosol]
RB1 Q383Nfs*3 [cytosol]
RB1 Y606* [cytosol]
RB1 Y756* [cytosol]
RB1 Y790* [cytosol]
RB1 T502Nfs*17 [cytosol]
RB1 Y709* [cytosol]
RB1 Y749* [cytosol]
RB1 T738_R775del [nucleoplasm]
hyperphosphorylated RB1 [nucleoplasm]
RB1 [cytosol]
p-S249-RB1 [nucleoplasm]
p-S230-RB1 [nucleoplasm]
p-T356-RB1 [nucleoplasm]
p-T826-RB1 [nucleoplasm]
p-T252-RB1 [nucleoplasm]
p-S807-RB1 [nucleoplasm]
p-T821-RB1 [nucleoplasm]
p-S795-RB1 [nucleoplasm]
p-S612-RB1 [nucleoplasm]
p-S780-RB1 [nucleoplasm]
p-S811-RB1 [nucleoplasm]
p-T373-RB1 [nucleoplasm]
RB1 [nucleoplasm]
p-S788-RB1 [nucleoplasm]
p-S608-RB1 [nucleoplasm]
Modified Residues
Name
Replacement of residues 635 to 639 by GPRSH
Disease
Name
Identifier
Synonyms
sebaceous carcinoma
DOID:4840
malignant Sebaceous tumor, malignant neoplasm of sebaceous gland
cancer
DOID:162
malignant tumor, malignant neoplasm, primary cancer
Cross References
RefSeq
NP_000312.2
OpenTargets
ENSG00000139687
ZINC - Substances
RB_HUMAN
ZINC target
P06400
PRO
P06400
PDB
4ELJ
,
1H25
,
2AZE
,
1AD6
,
1O9K
,
4ELL
,
1GUX
,
3POM
,
1PJM
,
1GH6
,
2QDJ
,
1N4M
,
4CRI
,
2R7G
,
3N5U
COSMIC
COSV57301811
HPA
ENSG00000139687-RB1
GeneCards
P06400
Ensembl
ENST00000267163
,
ENSP00000267163
,
ENSG00000139687
Pharos - Targets
P06400
ZINC - Predictions - Purchasable
RB_HUMAN
Orphanet
15191
Interactors (65)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01094 E2F1
2
E2F1 [nucleoplasm]
(R-HSA-68639)
p-E2F1 [nucleoplasm]
(R-HSA-187911)
0.97
30
UniProt:P03129 VE7
0.969
28
UniProt:Q13547 HDAC1
2
HDAC1 [nucleoplasm]
(R-HSA-205021)
monoSUMO1-K444,K476-HDAC1 [nucleoplasm]
(R-HSA-4616030)
0.955
18
UniProt:P03070 LT
0.927
9
UniProt:P03255 E1A
0.921
10
UniProt:O00716 E2F3
2
p-E2F3 [nucleoplasm]
(R-HSA-187933)
E2F3 [nucleoplasm]
(R-HSA-68655)
0.822
5
UniProt:Q14209 E2F2
1
E2F2 [nucleoplasm]
(R-HSA-68649)
0.78
5
UniProt:P06788 VE7
0.772
4
UniProt:P62136 PPP1CA
1
PPP1CA [cytosol]
(R-HSA-163525)
0.771
5
UniProt:Q16254 E2F4
1
E2F4 [nucleoplasm]
(R-HSA-68664)
0.757
6
UniProt:Q14188 TFDP2
1
TFDP2 [nucleoplasm]
(R-HSA-1362225)
0.744
5
UniProt:Q14186 TFDP1
1
TFDP1 [nucleoplasm]
(R-HSA-68652)
0.744
6
UniProt:Q00987 MDM2
11
PolyUb-MDM2 [nucleoplasm]
(R-HSA-6782472)
monoSUMO1-K182-MDM2 [nucleoplasm]
(R-HSA-3000408)
MDM2 [plasma membrane]
(R-HSA-416843)
MDM2 [endocytic vesicle membrane]
(R-HSA-416849)
p-5S,T-MDM2 [nucleoplasm]
(R-HSA-6804954)
PolyUb,p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6795669)
p-S166,S188,T218-MDM2 [nucleoplasm]
(R-HSA-6792862)
MDM2 [nucleoplasm]
(R-HSA-69486)
MDM2 [cytosol]
(R-HSA-198644)
p-S166,S188-MDM2 [cytosol]
(R-HSA-198638)
p-S166,S188-MDM2 [nucleoplasm]
(R-HSA-6793669)
0.734
5
UniProt:P24385 CCND1
4
CCND1 [nucleoplasm]
(R-HSA-113832)
CCND1 [cytosol]
(R-HSA-68328)
p-T286-CCND1 [nucleoplasm]
(R-HSA-75811)
p-T286-CCND1 [cytosol]
(R-HSA-75813)
0.73
5
UniProt:P04020 VE7
0.702
3
UniProt:P03255-2
0.702
3
UniProt:P06464 VE7
0.688
3
UniProt:Q13627 DYRK1A
1
DYRK1A [nucleoplasm]
(R-HSA-1362267)
0.67
4
UniProt:Q9Y463 DYR1B
0.67
4
UniProt:P06400 RB1
20
RB1 R661W [nucleoplasm]
(R-HSA-9659801)
RB1 C706F [nucleoplasm]
(R-HSA-9659812)
RB1 N480del [nucleoplasm]
(R-HSA-9659792)
RB1 C706Y [nucleoplasm]
(R-HSA-9659821)
RB1 R661Q [nucleoplasm]
(R-HSA-9659807)
RB1 I703_E737del [nucleoplasm]
(R-HSA-9661065)
RB1 R830_G887del [cytosol]
(R-HSA-9661059)
RB1 K791* [cytosol]
(R-HSA-9662284)
RB1 Q176* [cytosol]
(R-HSA-9661774)
RB1 S114* [cytosol]
(R-HSA-9661775)
RB1 K765* [cytosol]
(R-HSA-9662281)
RB1 W99* [cytosol]
(R-HSA-9661769)
RB1 S149* [cytosol]
(R-HSA-9661770)
RB1 E166* [cytosol]
(R-HSA-9661767)
RB1 G100* [cytosol]
(R-HSA-9661763)
RB1 E125* [cytosol]
(R-HSA-9661784)
RB1 Q121* [cytosol]
(R-HSA-9661780)
RB1 E184* [cytosol]
(R-HSA-9661781)
RB1 E137* [cytosol]
(R-HSA-9661782)
RB1 K745* [cytosol]
(R-HSA-9662288)
0.667
3
UniProt:P06465 VE7
0.647
3
UniProt:Q13363 CTBP1
3
monoSUMO1-K428-CTBP1 [nucleoplasm]
(R-HSA-3108200)
polySUMO2,3-K428-CTBP1 [nucleoplasm]
(R-HSA-3108226)
CTBP1 [nucleoplasm]
(R-HSA-212372)
0.643
3
UniProt:P52927
1
Hmga2 [nucleoplasm]
(R-MMU-1629831)
0.632
5
UniProt:P24941 CDK2
5
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
CDK2 [cytosol]
(R-HSA-157440)
CDK2 [nucleoplasm]
(R-HSA-68365)
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
0.623
3
UniProt:P30285 Cdk4
6
CDK4 [nucleoplasm]
(R-MMU-113730)
phospho-Cdk4(Thr 286) [nucleoplasm]
(R-MMU-182559)
Cdk4 [nucleoplasm]
(R-MMU-182567)
CDK4 [cytosol]
(R-MMU-68330)
CDK4 [nucleoplasm]
(R-MMU-113843)
phospho-p-T172-CDK4 [nucleoplasm]
(R-MMU-113830)
0.623
2
UniProt:Q16539 MAPK14
7
MAPK14 [secretory granule lumen]
(R-HSA-6803300)
MAPK14 [extracellular region]
(R-HSA-6806453)
MAPK14 [ficolin-1-rich granule lumen]
(R-HSA-6803280)
MAPK14 [nucleoplasm]
(R-HSA-446223)
MAPK14 [cytosol]
(R-HSA-428933)
p-T180,Y182-MAPK14 [cytosol]
(R-HSA-428935)
p-T180,Y182-MAPK14 [nucleoplasm]
(R-HSA-446227)
0.623
4
UniProt:P39880 CUX1
2
CUX1(1-339)-FGFR1(429-822) fusion [cytosol]
(R-HSA-1614371)
CUX1(1-339)-p-FGFR1(429-822) fusion [cytosol]
(R-HSA-1838991)
0.611
4
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.61
4
UniProt:Q15329 E2F5
1
E2F5 [nucleoplasm]
(R-HSA-68669)
0.609
2
UniProt:Q923E4 Sirt1
2
Sirt1 [nucleoplasm]
(R-MMU-5211238)
SIRT1 [nucleoplasm]
(R-MMU-427531)
0.602
4
UniProt:O96017 CHEK2
3
p-T68-CHEK2 [nucleoplasm]
(R-HSA-113825)
CHEK2 [nucleoplasm]
(R-HSA-113824)
p-S,3T-CHEK2 [nucleoplasm]
(R-HSA-5683784)
0.602
3
UniProt:Q14686 NCOA6
1
NCOA6 [nucleoplasm]
(R-HSA-376414)
0.593
3
UniProt:Q96PU4 UHRF2
1
UHRF2 [nucleoplasm]
(R-HSA-976050)
0.591
4
UniProt:Q13574-2 DGKZ
0.591
6
UniProt:P03255-1
0.589
2
UniProt:Q3TKT4 Smarca4
2
SMARCA4 [nucleoplasm]
(R-MMU-201686)
Smarca4 [nucleoplasm]
(R-MMU-9727480)
0.573
4
UniProt:Q93009 USP7
2
USP7 [cytosol]
(R-HSA-8853511)
USP7 [nucleoplasm]
(R-HSA-3215278)
0.571
8
UniProt:Q99708 RBBP8
4
p-S327,T847-RBBP8 [nucleoplasm]
(R-HSA-5684083)
RBBP8 [nucleoplasm]
(R-HSA-912399)
Ac-K-RBBP8 [nucleoplasm]
(R-HSA-5685955)
p-S327,T847,T859-RBBP8 [nucleoplasm]
(R-HSA-5684138)
0.564
2
UniProt:P03254 E1A
0.558
3
UniProt:O14757 CHEK1
3
CHEK1 [cytosol]
(R-HSA-205285)
CHEK1 [nucleoplasm]
(R-HSA-113826)
p-S317,S345-CHEK1 [nucleoplasm]
(R-HSA-113838)
0.558
3
UniProt:P0C6X7-PRO_0000037321 REP
0.556
3
UniProt:Q8VSP9 OSPF
0.544
2
IntAct:EBI-971875 DGKZ-MARCKS-PSD
0.544
2
UniProt:P55345 ANM2
0.544
3
UniProt:P42685 FRK
4
FRK [specific granule lumen]
(R-HSA-6801037)
FRK [extracellular region]
(R-HSA-6806235)
FRK [azurophil granule lumen]
(R-HSA-6799142)
p-Y387-FRK [cytosol]
(R-HSA-8847965)
0.544
3
UniProt:Q9R002 IFI2
0.544
5
UniProt:Q6ZUJ4 CC062
0.527
2
UniProt:Q5H9I0 TFDP3
0.527
3
UniProt:P40937 RFC5
1
RFC5 [nucleoplasm]
(R-HSA-68427)
0.527
2
UniProt:Q9NQ55 SSF1
0.527
2
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.527
2
UniProt:Q9Y676 MRPS18B
1
MRPS18B [mitochondrial inner membrane]
(R-HSA-5368234)
0.525
2
UniProt:O15151 MDM4
5
PolyUb-MDM4 [nucleoplasm]
(R-HSA-6782502)
p-S403-MDM4 [nucleoplasm]
(R-HSA-349461)
p-S346,S367,S403-MDM4 [nucleoplasm]
(R-HSA-349441)
PolyUb,p-S342,S367,S403-MDM4 [nucleoplasm]
(R-HSA-6804938)
MDM4 [nucleoplasm]
(R-HSA-349430)
0.524
4
UniProt:P24863 CCNC
1
CCNC [nucleoplasm]
(R-HSA-212418)
0.524
4
UniProt:Q86500-PRO_0000041225
0.524
3
UniProt:A0MPS7 A0MPS7
0.524
2
UniProt:P07197 NFM
0.524
2
UniProt:Q9UQ80 PA2G4
2
PA2G4 [extracellular region]
(R-HSA-6806200)
PA2G4 [azurophil granule lumen]
(R-HSA-6799205)
0.524
4
UniProt:Q00577 PURA
0.524
6
UniProt:O75150 RNF40
1
RNF40 [nucleoplasm]
(R-HSA-5689015)
0.508
3
UniProt:Q9UKV8 AGO2
2
AGO2 [nucleoplasm]
(R-HSA-5578701)
AGO2 [cytosol]
(R-HSA-209723)
0.499
3
UniProt:P29375 KDM5A
1
KDM5A [nucleoplasm]
(R-HSA-3215029)
0.499
2
UniProt:O43524 FOXO3
11
p-S215 FOXO3 [nucleoplasm]
(R-HSA-5687010)
p-S215 FOXO3 [cytosol]
(R-HSA-5687014)
FOXO3 [cytosol]
(R-HSA-5687032)
p-S43,S173,S294,S325-FOXO3 [nucleoplasm]
(R-HSA-8870627)
p-S43,S173,S294,S325-FOXO3 [cytosol]
(R-HSA-8870560)
FOXO3(?-673) [mitochondrial matrix]
(R-HSA-9841824)
Ac-K271,K290-FOXO3(?-673) [mitochondrial matrix]
(R-HSA-9841849)
Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm]
(R-HSA-9620514)
p-T32,S253,S315-FOXO3 [cytosol]
(R-HSA-9614413)
p-T32,S253,S315-FOXO3 [nucleoplasm]
(R-HSA-199289)
FOXO3 [nucleoplasm]
(R-HSA-199305)
0.499
2
UniProt:Q14653 IRF3
6
p-5S,T404-IRF3 [nucleoplasm]
(R-HSA-936418)
p-4S,T404-IRF3 [nucleoplasm]
(R-HSA-177654)
p-4S,T404-IRF3 [cytosol]
(R-HSA-166258)
IRF3(272-427) [cytosol]
(R-HSA-9729737)
IRF3(2-271) [cytosol]
(R-HSA-9729696)
IRF3 [cytosol]
(R-HSA-166251)
0.499
2
UniProt:Q5R372-2 RABGAP1L
0.488
2
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![RB1 A635Gfs*6 [cytosol] icon](/icon/R-ICO-013281.svg){kind=icon}
