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PA2G4 [azurophil granule lumen]
Stable Identifier
R-HSA-6799205
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
azurophil granule lumen
Synonyms
EBP1 (PA2G4), Proliferation-associated protein 2G4, PA2G4_HUMAN, EBP1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of azurophil granule lumen proteins (Homo sapiens)
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
PA2G4 [azurophil granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UQ80 PA2G4
Gene Names
PA2G4, EBP1
Chain
initiator methionine:, chain:2-394
Reference Genes
BioGPS Gene:5036 PA2G4
COSMIC (genes):PA2G4 PA2G4
CTD Gene:5036 PA2G4
dbSNP Gene:5036 PA2G4
ENSEMBL:ENSG00000170515 PA2G4
HGNC:8550 PA2G4
KEGG:hsa:5036 PA2G4
Monarch:5036 PA2G4
NCBI Gene:5036 PA2G4
OMIM:602145 PA2G4
UCSC:Q9UQ80 PA2G4
Reference Transcript
RefSeq:NM_006191.2 PA2G4
Other Identifiers
11723412_s_at
11757850_s_at
16752453
208676_PM_s_at
208676_s_at
214794_PM_at
214794_at
2970335
2970336
3170522
3417310
3417311
3417312
3417313
3417314
3417315
3417317
3417318
3417319
3417321
3417322
3417323
3417324
3417325
3417326
3417327
3417328
3417329
3417330
3417331
3417332
3417333
3417334
3417335
3417336
3417337
3417338
3417339
3417340
3417341
3417342
3417344
3876803
4020072
41600_at
5036
7956152
80456_s_at
A_23_P116679
A_32_P11181
A_33_P3227209
GE61650
GE84952
GO:0003676
GO:0003714
GO:0003723
GO:0005515
GO:0005576
GO:0005634
GO:0005730
GO:0005737
GO:0006355
GO:0006364
GO:0006417
GO:0016020
GO:0031625
GO:0035578
GO:0043066
GO:0043226
GO:0045597
GO:0045892
GO:0060090
GO:0070062
GO:0140110
GO:1990904
HMNXSV003044766
Hs.5181.2.S1_3p_at
Hs.5181.2.S1_3p_x_at
ILMN_1728984
PH_hs_0018140
TC12003244.hg
g4099505_3p_a_at
Participates
as a member of
Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)
Other forms of this molecule
PA2G4 [extracellular region]
Inferred To
BEST:CK00496 [azurophil granule lumen]
(Drosophila melanogaster)
cdb4 [azurophil granule lumen]
(Schizosaccharomyces pombe)
ARX1 [azurophil granule lumen]
(Saccharomyces cerevisiae)
Pa2g4 [azurophil granule lumen]
(Mus musculus)
Pa2g4 [azurophil granule lumen]
(Rattus norvegicus)
prlA [azurophil granule lumen]
(Dictyostelium discoideum)
pa2g4a [azurophil granule lumen]
(Danio rerio)
PA2G4 [azurophil granule lumen]
(Bos taurus)
PA2G4 [azurophil granule lumen]
(Caenorhabditis elegans)
PA2G4 [azurophil granule lumen]
(Canis familiaris)
PA2G4 [azurophil granule lumen]
(Gallus gallus)
PA2G4 [azurophil granule lumen]
(Plasmodium falciparum)
PA2G4 [azurophil granule lumen]
(Sus scrofa)
pa2g4 [azurophil granule lumen]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000303305
,
ENSP00000302886
OpenTargets
ENSG00000170515
HPA
ENSG00000170515-PA2G4
PRO
Q9UQ80
Pharos - Targets
Q9UQ80
GlyGen
Q9UQ80
PDB
6ZMI
,
2Q8K
,
7BHP
,
6CHT
,
6ZM7
,
3J2I
,
6ZMO
,
6WM8
,
6Z6N
,
6ZME
,
6Z6L
,
6SXO
,
6Z6M
,
6LSR
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96ST3 SIN3A
2
SIN3A [nucleoplasm]
(R-HSA-351657)
monoSUMO1-SIN3A [nucleoplasm]
(R-HSA-4086071)
0.602
4
UniProt:P62917 RPL8
3
RPL8 [cytosol]
(R-HSA-72490)
RPL8 [nucleoplasm]
(R-HSA-9630985)
3OHH216-RPL8 [nucleoplasm]
(R-HSA-9630976)
0.528
2
UniProt:Q15363 TMED2
5
TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-1911531)
TMED2 [endoplasmic reticulum membrane]
(R-HSA-5689480)
TMED2 [ER to Golgi transport vesicle membrane]
(R-HSA-5689847)
TMED2 [transport vesicle]
(R-HSA-6808806)
TMED2 [Golgi membrane]
(R-HSA-6808804)
0.527
2
UniProt:P10636-8 MAPT
3
MAPT-8 [cytosol]
(R-HSA-9619519)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
0.527
6
UniProt:P06400 RB1
20
RB1 R661W [nucleoplasm]
(R-HSA-9659801)
RB1 C706F [nucleoplasm]
(R-HSA-9659812)
RB1 N480del [nucleoplasm]
(R-HSA-9659792)
RB1 C706Y [nucleoplasm]
(R-HSA-9659821)
RB1 R661Q [nucleoplasm]
(R-HSA-9659807)
RB1 I703_E737del [nucleoplasm]
(R-HSA-9661065)
RB1 R830_G887del [cytosol]
(R-HSA-9661059)
RB1 K791* [cytosol]
(R-HSA-9662284)
RB1 Q176* [cytosol]
(R-HSA-9661774)
RB1 S114* [cytosol]
(R-HSA-9661775)
RB1 K765* [cytosol]
(R-HSA-9662281)
RB1 W99* [cytosol]
(R-HSA-9661769)
RB1 S149* [cytosol]
(R-HSA-9661770)
RB1 E166* [cytosol]
(R-HSA-9661767)
RB1 G100* [cytosol]
(R-HSA-9661763)
RB1 E125* [cytosol]
(R-HSA-9661784)
RB1 Q121* [cytosol]
(R-HSA-9661780)
RB1 E184* [cytosol]
(R-HSA-9661781)
RB1 E137* [cytosol]
(R-HSA-9661782)
RB1 K745* [cytosol]
(R-HSA-9662288)
0.524
4
UniProt:Q9NQT4 EXOSC5
2
EXOSC5 [cytosol]
(R-HSA-429889)
EXOSC5 [nucleoplasm]
(R-HSA-6791550)
0.519
2
UniProt:P19338 NCL
3
NCL [plasma membrane]
(R-HSA-9836466)
NCL [macropinosome membrane]
(R-HSA-9837666)
NCL [nucleoplasm]
(R-HSA-6791213)
0.499
2
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.491
3
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