Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PSMD11 [ficolin-1-rich granule lumen]
Stable Identifier
R-HSA-6800436
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
ficolin-1-rich granule lumen
Synonyms
26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory subunit S9, 26S proteasome regulatory subunit p44.5
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule lumen proteins (Homo sapiens)
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
PSMD11 [ficolin-1-rich granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00231 PSMD11
Gene Names
PSMD11
Chain
initiator methionine:, chain:2-422
Reference Genes
BioGPS Gene:5717 PSMD11
COSMIC (genes):PSMD11 PSMD11
CTD Gene:5717 PSMD11
dbSNP Gene:5717 PSMD11
ENSEMBL:ENSG00000108671 PSMD11
ENSEMBL_homo_sapiens_GENE:ENSG00000108671.11 PSMD11
HGNC:9556 PSMD11
KEGG Gene (Homo sapiens):5717 PSMD11
Monarch:5717 PSMD11
NCBI Gene:5717 PSMD11
OMIM:604449 PSMD11
UCSC:O00231 PSMD11
Reference Transcript
RefSeq:NM_002815.3 PSMD11
RefSeq:NM_001270482.1 PSMD11
Other Identifiers
11753142_a_at
11753982_a_at
1191_s_at
16833139
208776_PM_at
208776_at
208777_PM_s_at
208777_s_at
3717740
3717741
3717745
3717749
3717750
3717751
3717752
3717753
3717755
3717758
3717761
3717763
3717765
3717767
3717768
3717769
3717770
3717771
3717772
3717774
52399_at
5717
58557_at
58558_g_at
61789_i_at
8006392
AB003102_at
A_23_P207600
A_24_P73962
GE53109
GE85882
GO:0000502
GO:0005198
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005838
GO:0006511
GO:0008541
GO:0016020
GO:0022624
GO:0030154
GO:0030163
GO:0031410
GO:0032991
GO:0034774
GO:0043161
GO:0043226
GO:0043248
GO:0048863
GO:0065003
GO:1904813
HMNXSV003004469
Hs.90744.0.S2_3p_at
ILMN_1800952
PH_hs_0025894
TC17000376.hg
g2150045_3p_a_at
Participates
as a member of
Ficolin-rich granule lumen proteins [ficolin-1-rich granule lumen] (Homo sapiens)
Other forms of this molecule
PSMD11 [secretory granule lumen]
PSMD11 [extracellular region]
PSMD11 [nucleoplasm]
PSMD11 [cytosol]
Inferred To
rpn6 [ficolin-1-rich granule lumen]
(Schizosaccharomyces pombe)
psmd11 [ficolin-1-rich granule lumen]
(Xenopus tropicalis)
psmd11b [ficolin-1-rich granule lumen]
(Danio rerio)
PSMD11 [ficolin-1-rich granule lumen]
(Bos taurus)
PSMD11 [ficolin-1-rich granule lumen]
(Canis familiaris)
PSMD11 [ficolin-1-rich granule lumen]
(Gallus gallus)
PSMD11 [ficolin-1-rich granule lumen]
(Plasmodium falciparum)
PSMD11 [ficolin-1-rich granule lumen]
(Sus scrofa)
RPN6 [ficolin-1-rich granule lumen]
(Saccharomyces cerevisiae)
Rpn6 [ficolin-1-rich granule lumen]
(Drosophila melanogaster)
rpn-6.1 [ficolin-1-rich granule lumen]
(Caenorhabditis elegans)
psmD11 [ficolin-1-rich granule lumen]
(Dictyostelium discoideum)
Psmd11 [ficolin-1-rich granule lumen]
(Mus musculus)
Psmd11 [ficolin-1-rich granule lumen]
(Rattus norvegicus)
Cross References
RefSeq
NP_002806.2
,
NP_001257411.1
OpenTargets
ENSG00000108671
GeneCards
O00231
HPA
ENSG00000108671-PSMD11
Ensembl
ENSG00000108671
,
ENSP00000261712
,
ENST00000457654
,
ENST00000261712
,
ENST00000649012
,
ENSP00000497128
,
ENSP00000393185
PRO
O00231
Pharos - Targets
O00231
PDB
5T0I
,
5VHH
,
7W3B
,
5T0H
,
5GJQ
,
7W3A
,
7QYB
,
7QXN
,
5M32
,
5GJR
,
7QYA
,
5VHF
,
6MSB
,
5VFS
,
5VFR
,
7W37
,
8CVT
,
6MSK
,
5VGZ
,
5VFQ
,
6MSJ
,
6WJD
,
5VHS
,
7QXW
,
6MSH
,
5T0J
,
6MSG
,
5VHI
,
7W3M
,
7W3C
,
6MSE
,
7QXP
,
7W3K
,
6MSD
,
5VFU
,
5T0C
,
7W3J
,
5T0G
,
7W39
,
5VFT
,
7W3I
,
7W38
,
6WJN
,
7W3H
,
5LN3
,
7QY7
,
7W3G
,
7QXX
,
7W3F
,
5VFP
,
5L4K
,
7QXU
Interactors (37)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y5K5 UCHL5
2
UCHL5 [cytosol]
(R-HSA-1629778)
UCHL5 [nucleoplasm]
(R-HSA-5689584)
0.788
6
UniProt:Q9UNM6 PSMD13
5
PSMD13 [secretory granule lumen]
(R-HSA-6800983)
PSMD13 [extracellular region]
(R-HSA-6806469)
PSMD13 [ficolin-1-rich granule lumen]
(R-HSA-6800413)
PSMD13 [nucleoplasm]
(R-HSA-174326)
PSMD13 [cytosol]
(R-HSA-68794)
0.745
6
UniProt:P55036 PSMD4
1
PSMD4 [cytosol]
(R-HSA-68800)
0.745
5
UniProt:O75832 PSMD10
1
PSMD10 [cytosol]
(R-HSA-68788)
0.744
6
UniProt:O00232 PSMD12
5
PSMD12 [secretory granule lumen]
(R-HSA-6800934)
PSMD12 [extracellular region]
(R-HSA-6806480)
PSMD12 [ficolin-1-rich granule lumen]
(R-HSA-6800416)
PSMD12 [nucleoplasm]
(R-HSA-174339)
PSMD12 [cytosol]
(R-HSA-68792)
0.731
6
UniProt:P51665 PSMD7
5
PSMD7 [secretory granule lumen]
(R-HSA-6801008)
PSMD7 [extracellular region]
(R-HSA-6806488)
PSMD7 [ficolin-1-rich granule lumen]
(R-HSA-6800406)
PSMD7 [nucleoplasm]
(R-HSA-174309)
PSMD7 [cytosol]
(R-HSA-68806)
0.731
5
UniProt:P49721 PSMB2
2
PSMB2 [nucleoplasm]
(R-HSA-174335)
PSMB2 [cytosol]
(R-HSA-68744)
0.725
4
UniProt:P62195 PSMC5
2
PSMC5 [nucleoplasm]
(R-HSA-174312)
PSMC5 [cytosol]
(R-HSA-68780)
0.725
5
UniProt:P43686 PSMC4
2
PSMC4 [nucleoplasm]
(R-HSA-174315)
PSMC4 [cytosol]
(R-HSA-68777)
0.669
4
UniProt:Q15008 PSMD6
5
PSMD6 [secretory granule lumen]
(R-HSA-6801036)
PSMD6 [extracellular region]
(R-HSA-6806486)
PSMD6 [ficolin-1-rich granule lumen]
(R-HSA-6800440)
PSMD6 [nucleoplasm]
(R-HSA-174316)
PSMD6 [cytosol]
(R-HSA-68804)
0.667
4
UniProt:O00487 PSMD14
5
PSMD14 [secretory granule lumen]
(R-HSA-6800926)
PSMD14 [extracellular region]
(R-HSA-6806511)
PSMD14 [ficolin-1-rich granule lumen]
(R-HSA-6800419)
PSMD14 [nucleoplasm]
(R-HSA-174329)
PSMD14 [cytosol]
(R-HSA-68722)
0.648
3
UniProt:Q13200 PSMD2
5
PSMD2 [secretory granule lumen]
(R-HSA-6800919)
PSMD2 [extracellular region]
(R-HSA-6806479)
PSMD2 [ficolin-1-rich granule lumen]
(R-HSA-6800435)
PSMD2 [nucleoplasm]
(R-HSA-174311)
PSMD2 [cytosol]
(R-HSA-68796)
0.648
4
UniProt:O43242 PSMD3
5
PSMD3 [secretory granule lumen]
(R-HSA-6800873)
PSMD3 [extracellular region]
(R-HSA-6806443)
PSMD3 [ficolin-1-rich granule lumen]
(R-HSA-6800408)
PSMD3 [nucleoplasm]
(R-HSA-174328)
PSMD3 [cytosol]
(R-HSA-68798)
0.648
4
UniProt:Q99436 PSMB7
7
PSMB7(1-43) [cytosol]
(R-HSA-9908129)
pro-PSMB7 [cytosol]
(R-HSA-9908145)
PSMB7 [secretory granule lumen]
(R-HSA-6803279)
PSMB7 [extracellular region]
(R-HSA-6806449)
PSMB7 [ficolin-1-rich granule lumen]
(R-HSA-6803312)
PSMB7 [nucleoplasm]
(R-HSA-174331)
PSMB7 [cytosol]
(R-HSA-68759)
0.643
3
UniProt:P49720 PSMB3
2
PSMB3 [nucleoplasm]
(R-HSA-174341)
PSMB3 [cytosol]
(R-HSA-68747)
0.643
4
UniProt:Q16186 ADRM1
2
ADRM1 [nucleoplasm]
(R-HSA-9918361)
ADRM1 [cytosol]
(R-HSA-5665939)
0.643
5
UniProt:P10636-8 MAPT
3
p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol]
(R-HSA-9836400)
p-S262,S356,S396-MAPT-8 [cytosol]
(R-HSA-9619521)
MAPT-8 [cytosol]
(R-HSA-9619519)
0.643
6
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.597
4
UniProt:Q9BRP4 PAAF1
1
PAAF1 [cytosol]
(R-HSA-9907973)
0.564
2
UniProt:P61201 COPS2
2
COPS2 [cytosol]
(R-HSA-416971)
COPS2 [nucleoplasm]
(R-HSA-5697012)
0.556
3
UniProt:O43741 PRKAB2
2
PRKAB2 [cytosol]
(R-HSA-200413)
PRKAB2 [nucleoplasm]
(R-HSA-164096)
0.556
3
UniProt:P62333 PSMC6
2
PSMC6 [nucleoplasm]
(R-HSA-174319)
PSMC6 [cytosol]
(R-HSA-68783)
0.528
2
UniProt:P60896 SEM1
2
SEM1 [nucleoplasm]
(R-HSA-8866665)
SEM1 [cytosol]
(R-HSA-8866674)
0.528
2
UniProt:Q99460 PSMD1
4
PSMD1 [extracellular region]
(R-HSA-6806194)
PSMD1 [azurophil granule lumen]
(R-HSA-6798741)
PSMD1 [nucleoplasm]
(R-HSA-174348)
PSMD1 [cytosol]
(R-HSA-68786)
0.528
2
UniProt:P28070 PSMB4
4
PSMB4(1-45) [cytosol]
(R-HSA-9908122)
pro-PSMB4 [cytosol]
(R-HSA-9908138)
PSMB4 [nucleoplasm]
(R-HSA-174343)
PSMB4 [cytosol]
(R-HSA-68750)
0.527
2
UniProt:P54578 USP14
1
USP14 [cytosol]
(R-HSA-5689541)
0.527
2
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:Q53HC0 CCD92
0.527
3
UniProt:Q16401 PSMD5
1
PSMD5 [cytosol]
(R-HSA-68802)
0.527
3
UniProt:P20618 PSMB1
7
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [cytosol]
(R-HSA-68738)
0.527
3
UniProt:P28065 PSMB9
3
PSMB9(1-20) [cytosol]
(R-HSA-9908132)
PSMB9 [cytosol]
(R-HSA-68765)
pro-PSMB9 [cytosol]
(R-HSA-9908136)
0.527
4
UniProt:P62191 PSMC1
2
PSMC1 [nucleoplasm]
(R-HSA-174338)
PSMC1 [cytosol]
(R-HSA-68768)
0.527
2
UniProt:P25787 PSMA2
5
PSMA2 [secretory granule lumen]
(R-HSA-6803329)
PSMA2 [extracellular region]
(R-HSA-6806506)
PSMA2 [ficolin-1-rich granule lumen]
(R-HSA-6803285)
PSMA2 [nucleoplasm]
(R-HSA-174345)
PSMA2 [cytosol]
(R-HSA-68726)
0.527
2
UniProt:P17980 PSMC3
5
PSMC3 [secretory granule lumen]
(R-HSA-6800917)
PSMC3 [extracellular region]
(R-HSA-6806496)
PSMC3 [ficolin-1-rich granule lumen]
(R-HSA-6800429)
PSMC3 [nucleoplasm]
(R-HSA-174313)
PSMC3 [cytosol]
(R-HSA-68774)
0.527
2
UniProt:Q96LA8 PRMT6
1
PRMT6 [nucleoplasm]
(R-HSA-5226884)
0.508
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
14
UniProt:P04578-PRO_0000038427 ENV
0.462
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text