SEM1 [nucleoplasm]

Stable Identifier
R-HSA-8866665
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SHFM1, DSS1, 26S proteasome complex subunit DSS1, DSS1_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
18775730 Identification of a specific motif of the DSS1 protein required for proteasome interaction and p53 protein degradation

Tennant, RW, Dang, H, Cannon, RE, Humble, MM, Darden, TA, Trempus, CS, Williams, JG, Chang, FM, Betz, BL, Johnson, K, Wei, SJ

J. Mol. Biol. 2008
External Reference Information
External Reference
UniProt:P60896 SEM1
Gene Names
SEM1, DSS1, SHFDG1, SHFM1, C7orf76
Chain
chain:1-70
Reference Genes
BioGPS Gene:7979 SEM1
COSMIC (genes):SEM1 SEM1
CTD Gene:7979 SEM1
dbSNP Gene:7979 SEM1
ENSEMBL:ENSG00000127922 SEM1
ENSEMBL_homo_sapiens_GENE:ENSG00000127922.10 SEM1
KEGG Gene (Homo sapiens):7979 SEM1
Monarch:7979 SEM1
NCBI Gene:7979 SEM1
OMIM:601285 SEM1
Reference Transcript
Other Identifiers
11757388_x_at
11757676_x_at
11758812_at
202276_PM_at
202276_at
2818204
2818205
3062381
3062382
3062389
3062398
3062399
38744_at
7979
8141133
A_23_P42664
GE62879
GO:0000502
GO:0000724
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006281
GO:0006310
GO:0006406
GO:0006913
GO:0008541
GO:0030163
GO:0032039
GO:0032991
GO:0043161
GO:0043226
GO:0043248
GO:0065003
HMNXSV003004148
ILMN_1794505
PH_hs_0016340
PH_hs_0032700
U41515_at
Participates
as a component of
Other forms of this molecule
SEM1 [cytosol]
Inferred To
Ghost homologue of SEM1 [nucleoplasm] (Bos taurus)
Ghost homologue of SEM1 [nucleoplasm] (Caenorhabditis elegans)
Ghost homologue of SEM1 [nucleoplasm] (Canis familiaris)
Ghost homologue of SEM1 [nucleoplasm] (Danio rerio)
Ghost homologue of SEM1 [nucleoplasm] (Dictyostelium discoideum)
Ghost homologue of SEM1 [nucleoplasm] (Drosophila melanogaster)
Ghost homologue of SEM1 [nucleoplasm] (Gallus gallus)
Ghost homologue of SEM1 [nucleoplasm] (Mus musculus)
Ghost homologue of SEM1 [nucleoplasm] (Rattus norvegicus)
Ghost homologue of SEM1 [nucleoplasm] (Sus scrofa)
Cross References
RefSeq
OpenTargets
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (28)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P51587 BRCA2  20 0.83 10
 UniProt:Q5JVF3 PCID2      0.666 4
 UniProt:O43242 PSMD3  5 0.666 4
 UniProt:Q5JVF3-1 PCID2      0.611 3
 UniProt:Q01658 DR1  1 0.556 3
 UniProt:Q00403 GTF2B  1 0.556 3
 UniProt:Q9Y5Q9 GTF3C3  1 0.556 3
 UniProt:P35240-4 NF2      0.556 3
 UniProt:Q6NUL7 Q6NUL7      0.556 3
 UniProt:Q8WXH2 JPH3      0.556 3
 UniProt:P35637 FUS  1 0.556 3
 UniProt:Q5S007 LRRK2  1 0.556 3
 UniProt:P28799 GRN  2 0.556 3
 UniProt:P00441 SOD1  5 0.556 3
 UniProt:O00231 PSMD11  5 0.528 2
 UniProt:O60318 GANP      0.527 2
 UniProt:Q15386 UBE3C  1 0.527 4
 UniProt:Q9Y4E8 USP25  1 0.527 2
 UniProt:Q9UHD9 UBQLN2  1 0.527 3
 UniProt:O75832 PSMD10  2 0.527 2
 UniProt:Q9Y5K5 UCHL5  2 0.527 2
 UniProt:Q06323 PSME1  2 0.527 2
 UniProt:P54578 USP14  1 0.527 2
 UniProt:P35998 PSMC2  5 0.527 3
 UniProt:Q9BRP4 PAAF1      0.527 2
 UniProt:P54727 RAD23B  2 0.527 3
 UniProt:Q14997 PSME4  1 0.527 2
 UniProt:Q16186 ADRM1  1 0.462 3
Cite Us!