Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PSMD7 [cytosol]
Stable Identifier
R-HSA-68806
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
26S proteasome non-ATPase regulatory subunit 7, 26S proteasome regulatory subunit S12, Proteasome subunit p40, Mov34 protein homolog, 26S proteasome regulatory subunit RPN8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G1/S DNA Damage Checkpoints (Homo sapiens)
p53-Dependent G1/S DNA damage checkpoint (Homo sapiens)
p53-Dependent G1 DNA Damage Response (Homo sapiens)
Stabilization of p53 (Homo sapiens)
Autodegradation of the E3 ubiquitin ligase COP1 (Homo sapiens)
Proteasome mediated degradation of COP1 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
p53-Independent G1/S DNA damage checkpoint (Homo sapiens)
p53-Independent DNA Damage Response (Homo sapiens)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Homo sapiens)
Proteolytic degradation of ubiquitinated-Cdc25A (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Separation of Sister Chromatids (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Homo sapiens)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Proteasome-mediated degradation of PolyUb-FBXL7 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
GTSE1 facilitates proteasome-mediated degradation of TP53 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
Degradation of multiubiquitinated cell cycle proteins (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of Securin (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)
Degradation multiubiquitinated Cyclin A (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Regulation of APC/C activators between G1/S and early anaphase (Homo sapiens)
SCF-beta-TrCP mediated degradation of Emi1 (Homo sapiens)
SCF-mediated degradation of Emi1 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Ubiquitinated Cdc6 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Orc1 removal from chromatin (Homo sapiens)
Ubiquitinated Orc1 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Ubiquitin-dependent degradation of Cyclin D (Homo sapiens)
Proteasome mediated degradation of Cyclin D1 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
KEAP1-NFE2L2 pathway (Homo sapiens)
26S proteasome degrades Ub-NFE2L2 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ub UBXN7 is degraded by the 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Cellular response to hypoxia (Homo sapiens)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Homo sapiens)
Proteasome proteolyzes ub-HIF-alpha (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Ubiquitinated Cdc6 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Orc1 removal from chromatin (Homo sapiens)
Ubiquitinated Orc1 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
Signaling by ROBO receptors (Homo sapiens)
Regulation of expression of SLITs and ROBOs (Homo sapiens)
Proteasome degrades ubiquitinated ROBO3.1 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Hh mutants abrogate ligand secretion (Homo sapiens)
Hh mutants are degraded by ERAD (Homo sapiens)
processing defective Hh variants are degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
ABC transporter disorders (Homo sapiens)
Defective CFTR causes cystic fibrosis (Homo sapiens)
CFTR F508del is degraded by the 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
Vif-mediated degradation of APOBEC3G (Homo sapiens)
Proteosome-mediated degradation of APOBEC3G (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Vpu mediated degradation of CD4 (Homo sapiens)
Degradation of ubiquitinated CD4 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Homo sapiens)
26S proteasome degrades TP73 polyubiquitinated by ITCH (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
Regulation of RUNX2 expression and activity (Homo sapiens)
Proteasome degrades PolyUb-RUNX2 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Proteasome degrades polyubiquitinated RUNX2 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing-Cross presentation (Homo sapiens)
Cross-presentation of soluble exogenous antigens (endosomes) (Homo sapiens)
Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
Proteasomal cleavage of substrate (26S proteasome catalyst) (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Proteasomal cleavage of substrate (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Downstream signaling events of B Cell Receptor (BCR) (Homo sapiens)
Activation of NF-kappaB in B cells (Homo sapiens)
Ubiquitinated IkB is degraded (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
TNFR2 non-canonical NF-kB pathway (Homo sapiens)
26Sproteasome degrades K48polyUb-NIK (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
NIK-->noncanonical NF-kB signaling (Homo sapiens)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Protesomal degradation of K48polyUb-TRAF3 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Dectin-1 mediated noncanonical NF-kB signaling (Homo sapiens)
26S proteasome processes p-7S-p100:RELB to form p52:RELB (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated NF-kB activation (Homo sapiens)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of polyamines (Homo sapiens)
Regulation of ornithine decarboxylase (ODC) (Homo sapiens)
26S proteosome degrades ODC holoenzyme complex (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Metabolism of RNA (Homo sapiens)
Regulation of mRNA stability by proteins that bind AU-rich elements (Homo sapiens)
AUF1 (hnRNP D0) binds and destabilizes mRNA (Homo sapiens)
AUF1:mRNA complex is destroyed (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
UCH proteinases (Homo sapiens)
ADRM1 binds 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ADRM1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ADRM1:26S proteaseome binds UCHL5 (Homo sapiens)
ADRM1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ADRM1:26S proteasome:UCHL5 [cytosol] (Homo sapiens)
ADRM1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
ADRM1:26S proteaseome binds USP14 (Homo sapiens)
ADRM1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ADRM1:26S proteasome:USP14 [cytosol] (Homo sapiens)
ADRM1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Neddylation (Homo sapiens)
26S proteasome degrades HIFalpha (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
26S proteasome degrades Ub-NFE2L2 (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
26S- and NUB1-mediated degradation of NEDD8, UBD and their conjugates (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
NEDD8 and UBD bind NUB1 and the 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
NEDD8,UBD:NUB1:26S proteasome [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
ub UBXN7 is degraded by the 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Proteasome assembly (Homo sapiens)
Formation of the 19S regulatory particle lid (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Formation of the 19S regulatory particle precursor (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
19S RP precursor [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Formation of the 26S proteasome (Homo sapiens)
19S RP precursor [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Formation of the lid particle 2 (LP2) (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Formation of the spermatoproteasome (Homo sapiens)
19S RP precursor [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Spermatoproteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
PSMD11 binds PSMD7:PSMD12:PSMD13:PSMD14 (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
PTEN Regulation (Homo sapiens)
Regulation of PTEN stability and activity (Homo sapiens)
Proteasome degrades polyubiquitinated PTEN (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
Regulation of RAS by GAPs (Homo sapiens)
NF1 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
MAPK6/MAPK4 signaling (Homo sapiens)
MAPK6 is degraded by the 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
Degradation of GLI1 by the proteasome (Homo sapiens)
GLI1 is degraded by the proteasome after ubiquitination by ITCH (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Degradation of GLI2 by the proteasome (Homo sapiens)
GLI2 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
GLI3 is processed to GLI3R by the proteasome (Homo sapiens)
GLI3 is partially degraded by the proteasome to yield the GLI3 repressor (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Hedgehog 'on' state (Homo sapiens)
ub-GLI is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Hedgehog ligand biogenesis (Homo sapiens)
Hh C-terminal fragments are degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
PCP/CE pathway (Homo sapiens)
Asymmetric localization of PCP proteins (Homo sapiens)
PRICKLE1 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
Degradation of ubiquitinated beta catenin by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Degradation of AXIN (Homo sapiens)
Ub-RibC-AXIN is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Ubiquitinated AXIN is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Degradation of DVL (Homo sapiens)
Ubiquitinated DVL is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Ubiquitinated DVL1 is degraded by the proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
misfolded CFTR is degraded by the 26S proteasome (Homo sapiens)
26S proteasome [cytosol] (Homo sapiens)
19S regulatory particle [cytosol] (Homo sapiens)
19S RP lid [cytosol] (Homo sapiens)
19S RP lid particle 2 [cytosol] (Homo sapiens)
19S RP Lid Module 1 [cytosol] (Homo sapiens)
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
PSMD7 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51665 PSMD7
Gene Names
PSMD7, MOV34L
Chain
chain:1-324
Reference Genes
BioGPS Gene:5713 PSMD7
COSMIC (genes):PSMD7 PSMD7
CTD Gene:5713 PSMD7
dbSNP Gene:5713 PSMD7
ENSEMBL:ENSG00000103035 PSMD7
ENSEMBL_homo_sapiens_GENE:ENSG00000103035.11 PSMD7
HGNC:9565 PSMD7
KEGG Gene (Homo sapiens):5713 PSMD7
Monarch:5713 PSMD7
NCBI Gene:5713 PSMD7
OMIM:157970 PSMD7
UCSC:P51665 PSMD7
Reference Transcript
RefSeq:NM_002811.4 PSMD7
Other Identifiers
11729113_a_at
11729114_s_at
11746059_a_at
16821021
201705_PM_at
201705_at
3668618
3668619
3668625
3668626
3668627
3668628
3668629
3668631
3668634
3668635
3668636
3668637
3668638
3668639
3668640
40276_at
5713
7997230
945_at
A_14_P114737
A_23_P106741
D50063_at
GE57237
GO:0000502
GO:0003824
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005829
GO:0005838
GO:0008233
GO:0008237
GO:0016020
GO:0016787
GO:0030163
GO:0031410
GO:0034774
GO:0042803
GO:0043161
GO:0043226
GO:0070062
GO:0140096
GO:1904813
HMNXSV003019799
ILMN_1776173
PH_hs_0025797
TC16000612.hg
g4506230_3p_at
Participates
as an input of
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Homo sapiens)
as a component of
PSMD7:PSMD12:PSMD13:PSMD14 [cytosol] (Homo sapiens)
Other forms of this molecule
PSMD7 [secretory granule lumen]
PSMD7 [extracellular region]
PSMD7 [ficolin-1-rich granule lumen]
PSMD7 [nucleoplasm]
Inferred To
RPN8 [cytosol]
(Saccharomyces cerevisiae)
rpn-8 [cytosol]
(Caenorhabditis elegans)
Rpn8 [cytosol]
(Drosophila melanogaster)
PSMD7 [cytosol]
(Bos taurus)
PSMD7 [cytosol]
(Canis familiaris)
PSMD7 [cytosol]
(Gallus gallus)
PSMD7 [cytosol]
(Plasmodium falciparum)
PSMD7 [cytosol]
(Sus scrofa)
Psmd7 [cytosol]
(Mus musculus)
Psmd7 [cytosol]
(Rattus norvegicus)
psmd7 [cytosol]
(Danio rerio)
psmd7 [cytosol]
(Xenopus tropicalis)
psmD7 [cytosol]
(Dictyostelium discoideum)
rpn8 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_002802.2
OpenTargets
ENSG00000103035
GeneCards
P51665
HPA
ENSG00000103035-PSMD7
Ensembl
ENSP00000219313
,
ENST00000219313
,
ENSG00000103035
PRO
P51665
Pharos - Targets
P51665
PDB
7W39
,
5VGZ
,
5VFR
,
5VFS
,
7W38
,
5T0I
,
7W37
,
5VFP
,
5T0H
,
5VFQ
,
2O96
,
5T0C
,
2O95
,
6MSD
,
7QXN
,
5VFU
,
5VHH
,
6MSB
,
5L4K
,
7W3J
,
7QYA
,
7QY7
,
7W3I
,
6WJN
,
7QXX
,
6MSJ
,
7W3G
,
5VHS
,
7W3H
,
6WJD
,
5T0J
,
8CVT
,
7QXW
,
6MSK
,
5GJQ
,
7W3C
,
5VHI
,
7W3F
,
7QXP
,
5GJR
,
6MSH
,
5T0G
,
7QXU
,
6MSG
,
5VHF
,
7QYB
,
7W3M
,
7W3A
,
5VFT
,
7W3B
,
5LN3
,
7W3K
,
5M32
Interactors (38)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00487 PSMD14
5
PSMD14 [secretory granule lumen]
(R-HSA-6800926)
PSMD14 [extracellular region]
(R-HSA-6806511)
PSMD14 [ficolin-1-rich granule lumen]
(R-HSA-6800419)
PSMD14 [nucleoplasm]
(R-HSA-174329)
PSMD14 [cytosol]
(R-HSA-68722)
0.904
16
UniProt:Q15008 PSMD6
5
PSMD6 [secretory granule lumen]
(R-HSA-6801036)
PSMD6 [extracellular region]
(R-HSA-6806486)
PSMD6 [ficolin-1-rich granule lumen]
(R-HSA-6800440)
PSMD6 [nucleoplasm]
(R-HSA-174316)
PSMD6 [cytosol]
(R-HSA-68804)
0.802
6
UniProt:Q9Y5K5 UCHL5
2
UCHL5 [cytosol]
(R-HSA-1629778)
UCHL5 [nucleoplasm]
(R-HSA-5689584)
0.788
6
UniProt:P62195 PSMC5
2
PSMC5 [nucleoplasm]
(R-HSA-174312)
PSMC5 [cytosol]
(R-HSA-68780)
0.788
6
UniProt:P62191 PSMC1
2
PSMC1 [nucleoplasm]
(R-HSA-174338)
PSMC1 [cytosol]
(R-HSA-68768)
0.788
6
UniProt:P62333 PSMC6
2
PSMC6 [nucleoplasm]
(R-HSA-174319)
PSMC6 [cytosol]
(R-HSA-68783)
0.745
4
UniProt:P43686 PSMC4
2
PSMC4 [nucleoplasm]
(R-HSA-174315)
PSMC4 [cytosol]
(R-HSA-68777)
0.744
6
UniProt:O75832 PSMD10
1
PSMD10 [cytosol]
(R-HSA-68788)
0.744
5
UniProt:O00231 PSMD11
5
PSMD11 [secretory granule lumen]
(R-HSA-6800943)
PSMD11 [extracellular region]
(R-HSA-6806441)
PSMD11 [ficolin-1-rich granule lumen]
(R-HSA-6800436)
PSMD11 [nucleoplasm]
(R-HSA-174327)
PSMD11 [cytosol]
(R-HSA-68790)
0.731
5
UniProt:O00232 PSMD12
5
PSMD12 [secretory granule lumen]
(R-HSA-6800934)
PSMD12 [extracellular region]
(R-HSA-6806480)
PSMD12 [ficolin-1-rich granule lumen]
(R-HSA-6800416)
PSMD12 [nucleoplasm]
(R-HSA-174339)
PSMD12 [cytosol]
(R-HSA-68792)
0.725
5
UniProt:Q16186 ADRM1
2
ADRM1 [nucleoplasm]
(R-HSA-9918361)
ADRM1 [cytosol]
(R-HSA-5665939)
0.725
5
UniProt:Q13200 PSMD2
5
PSMD2 [secretory granule lumen]
(R-HSA-6800919)
PSMD2 [extracellular region]
(R-HSA-6806479)
PSMD2 [ficolin-1-rich granule lumen]
(R-HSA-6800435)
PSMD2 [nucleoplasm]
(R-HSA-174311)
PSMD2 [cytosol]
(R-HSA-68796)
0.725
6
UniProt:O43242 PSMD3
5
PSMD3 [secretory granule lumen]
(R-HSA-6800873)
PSMD3 [extracellular region]
(R-HSA-6806443)
PSMD3 [ficolin-1-rich granule lumen]
(R-HSA-6800408)
PSMD3 [nucleoplasm]
(R-HSA-174328)
PSMD3 [cytosol]
(R-HSA-68798)
0.725
5
UniProt:Q9UNM6 PSMD13
5
PSMD13 [secretory granule lumen]
(R-HSA-6800983)
PSMD13 [extracellular region]
(R-HSA-6806469)
PSMD13 [ficolin-1-rich granule lumen]
(R-HSA-6800413)
PSMD13 [nucleoplasm]
(R-HSA-174326)
PSMD13 [cytosol]
(R-HSA-68794)
0.669
4
UniProt:Q9BRP4 PAAF1
1
PAAF1 [cytosol]
(R-HSA-9907973)
0.669
4
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
10
UniProt:P55036 PSMD4
1
PSMD4 [cytosol]
(R-HSA-68800)
0.643
4
UniProt:Q16401 PSMD5
1
PSMD5 [cytosol]
(R-HSA-68802)
0.643
4
UniProt:P20618 PSMB1
7
PSMB1(1-28) [cytosol]
(R-HSA-9908143)
pro-PSMB1 [cytosol]
(R-HSA-9908139)
PSMB1 [secretory granule lumen]
(R-HSA-6803287)
PSMB1 [extracellular region]
(R-HSA-6806477)
PSMB1 [ficolin-1-rich granule lumen]
(R-HSA-6803340)
PSMB1 [nucleoplasm]
(R-HSA-174347)
PSMB1 [cytosol]
(R-HSA-68738)
0.643
3
UniProt:P48556 PSMD8
2
PSMD8 [nucleoplasm]
(R-HSA-174318)
PSMD8 [cytosol]
(R-HSA-68808)
0.643
4
UniProt:P28065 PSMB9
3
PSMB9(1-20) [cytosol]
(R-HSA-9908132)
PSMB9 [cytosol]
(R-HSA-68765)
pro-PSMB9 [cytosol]
(R-HSA-9908136)
0.643
5
UniProt:P17980 PSMC3
5
PSMC3 [secretory granule lumen]
(R-HSA-6800917)
PSMC3 [extracellular region]
(R-HSA-6806496)
PSMC3 [ficolin-1-rich granule lumen]
(R-HSA-6800429)
PSMC3 [nucleoplasm]
(R-HSA-174313)
PSMC3 [cytosol]
(R-HSA-68774)
0.643
4
UniProt:Q9Y4K3 TRAF6
8
K48polyUb-TRAF6 [cytosol]
(R-HSA-6783233)
PolyUb-TRAF6 [cytosol]
(R-HSA-6782845)
TRAF6 [endosome membrane]
(R-HSA-450272)
K63polyUb-TRAF6 [endosome membrane]
(R-HSA-450227)
TRAF6 [cytosol]
(R-HSA-166366)
K63polyUb-TRAF6 [cytosol]
(R-HSA-2685681)
K63polyUb-TRAF6 [plasma membrane]
(R-HSA-936980)
TRAF6 [plasma membrane]
(R-HSA-936955)
0.589
2
UniProt:P54252 ATXN3
2
ATXN3 [nucleoplasm]
(R-HSA-6783285)
ATXN3 [cytosol]
(R-HSA-5625607)
0.556
9
UniProt:Q5VTR2 RNF20
2
RNF20 [cytosol]
(R-HSA-9715141)
RNF20 [nucleoplasm]
(R-HSA-5689011)
0.527
2
UniProt:Q96EN9 REX1B
0.527
3
UniProt:Q01850 CDR2
0.527
2
UniProt:Q53HC0 CCD92
0.527
2
UniProt:O60826 CCDC22
2
CCDC22 [nucleoplasm]
(R-HSA-8955644)
CCDC22 [cytosol]
(R-HSA-8955640)
0.527
2
UniProt:P35998 PSMC2
5
PSMC2 [secretory granule lumen]
(R-HSA-6800994)
PSMC2 [extracellular region]
(R-HSA-6806472)
PSMC2 [ficolin-1-rich granule lumen]
(R-HSA-6800421)
PSMC2 [nucleoplasm]
(R-HSA-174332)
PSMC2 [cytosol]
(R-HSA-68771)
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.527
9
UniProt:Q99460 PSMD1
4
PSMD1 [extracellular region]
(R-HSA-6806194)
PSMD1 [azurophil granule lumen]
(R-HSA-6798741)
PSMD1 [nucleoplasm]
(R-HSA-174348)
PSMD1 [cytosol]
(R-HSA-68786)
0.527
3
UniProt:Q86UP2 KTN1
4
KTN1 [plasma membrane]
(R-HSA-9696518)
p-KTN1 [endoplasmic reticulum lumen]
(R-HSA-8956968)
KTN1 [endoplasmic reticulum lumen]
(R-HSA-8956694)
KTN1 [endoplasmic reticulum membrane]
(R-HSA-201604)
0.527
2
UniProt:Q5VIR6 VPS53
1
VPS53 [trans-Golgi network membrane]
(R-HSA-6811031)
0.527
2
UniProt:Q6PJG6 BRAT1
0.527
2
UniProt:P49720 PSMB3
2
PSMB3 [nucleoplasm]
(R-HSA-174341)
PSMB3 [cytosol]
(R-HSA-68747)
0.527
3
UniProt:P54252-1 ATXN3
0.499
2
UniProt:P04578-PRO_0000038427 ENV
0.462
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text