Reactome | PSMD1 [azurophil granule lumen]

PSMD1 [azurophil granule lumen]

Stable Identifier

R-HSA-6798741

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

azurophil granule lumen

Synonyms

26S proteasome non-ATPase regulatory subunit 1, 26S proteasome regulatory subunit S1, 26S proteasome subunit p112, RPN2

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99460 PSMD1

Gene Names

PSMD1

Chain

chain:1-953

Reference Genes

BioGPS Gene:5707 PSMD1

COSMIC (genes):PSMD1 PSMD1

CTD Gene:5707 PSMD1

dbSNP Gene:5707 PSMD1

ENSEMBL:ENSG00000173692.14 PSMD1

HGNC:9554 PSMD1

KEGG Gene (Homo sapiens):5707 PSMD1

Monarch:5707 PSMD1

NCBI Gene:5707 PSMD1

OMIM:617842 PSMD1

UCSC:Q99460 PSMD1

Reference Transcript

Other Identifiers

0003610446

11743902_at

11756579_a_at

1314_at

16892039

201198_PM_s_at

201198_s_at

201199_PM_s_at

201199_s_at

2531713

2531714

2531715

2531717

2531718

2531719

2531720

2531721

2531722

2531723

2531724

2531726

2531728

2531729

2531730

2531731

2531732

2531733

2531737

2531748

2531750

2531753

2531755

2531758

2531761

2531762

2531763

2531767

2531768

2531769

2531770

2531771

51788_at

5707

8049016

A_23_P209740

A_24_P128205

D44466_at

GE57222

GO:0000502

GO:0005515

GO:0005576

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005764

GO:0005773

GO:0005829

GO:0005838

GO:0008540

GO:0016020

GO:0022624

GO:0030163

GO:0030234

GO:0031410

GO:0031625

GO:0032991

GO:0034515

GO:0035578

GO:0042176

GO:0043161

GO:0043226

GO:0050790

GO:0098772

HMNXSV003045385

Hs.3887.0.S1_3p_a_at

ILMN_1702837

PH_hs_0000438

TC02001386.hg

TC02003882.hg

g4506224_3p_a_at

Participates

as a member of

Azurophil granule lumen proteins [azurophil granule lumen] (Homo sapiens)

Other forms of this molecule

PSMD1 [extracellular region]

PSMD1 [nucleoplasm]

PSMD1 [cytosol]

Inferred To

PSMD1 [azurophil granule lumen] (Bos taurus)

PSMD1 [azurophil granule lumen] (Canis familiaris)

PSMD1 [azurophil granule lumen] (Danio rerio)

PSMD1 [azurophil granule lumen] (Gallus gallus)

PSMD1 [azurophil granule lumen] (Plasmodium falciparum)

PSMD1 [azurophil granule lumen] (Sus scrofa)

Psmd1 [azurophil granule lumen] (Mus musculus)

Psmd1 [azurophil granule lumen] (Rattus norvegicus)

RPN2 [azurophil granule lumen] (Saccharomyces cerevisiae)

Rpn2 [azurophil granule lumen] (Drosophila melanogaster)

rpn-2 [azurophil granule lumen] (Caenorhabditis elegans)

rpn2 [azurophil granule lumen] (Schizosaccharomyces pombe)

psmD1 [azurophil granule lumen] (Dictyostelium discoideum)

psmd1 [azurophil granule lumen] (Xenopus tropicalis)

Cross References

RefSeq

NP_002798.2, NP_001177966.1

OpenTargets

ENSG00000173692

HPA

ENSG00000173692-PSMD1

GeneCards

Q99460

Ensembl

ENSP00000362738, ENSG00000173692, ENSP00000309474, ENSP00000503068, ENST00000308696, ENST00000373635, ENST00000677230

PRO

Q99460

Pharos - Targets

Q99460

PDB

6MSK, 6OI4, 6MSJ, 5VGZ, 5VFQ, 5VFS, 5L4K, 5VFR, 6WJD, 5VFT, 6UYI, 5VHF, 5LN3, 5M32, 5T0C, 6WJN, 6UYJ, 5VHH, 5VFU, 6MSB, 5GJQ, 5VHI, 6MSD, 5T0H, 5GJR, 5T0G, 6MSE, 5V1Z, 5T0I, 5VHS, 5V1Y, 6MSG, 5T0J, 6CO4, 5VFP, 6MSH

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q16186 ADRM1	1	ADRM1 [cytosol] (R-HSA-5665939)	0.676	5
UniProt:O00487 PSMD14	5	PSMD14 [secretory granule lumen] (R-HSA-6800926) PSMD14 [extracellular region] (R-HSA-6806511) PSMD14 [ficolin-1-rich granule lumen] (R-HSA-6800419) PSMD14 [nucleoplasm] (R-HSA-174329) PSMD14 [cytosol] (R-HSA-68722)	0.564	2
UniProt:Q9Y5K5 UCHL5	2	UCHL5 [cytosol] (R-HSA-1629778) UCHL5 [nucleoplasm] (R-HSA-5689584)	0.564	3
UniProt:P62333 PSMC6	2	PSMC6 [nucleoplasm] (R-HSA-174319) PSMC6 [cytosol] (R-HSA-68783)	0.553	2

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