Reactome | PSMD5 [cytosol]

PSMD5 [cytosol]

Stable Identifier

R-HSA-68802

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

26S proteasome non-ATPase regulatory subunit 5, 26S proteasome subunit S5B, 26S protease subunit S5 basic, Yeast Hsm3 ortholog

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16401 PSMD5

Gene Names

PSMD5, KIAA0072

Chain

initiator methionine:, chain:2-504

Reference Genes

BioGPS Gene:5711 PSMD5

COSMIC (genes):PSMD5 PSMD5

CTD Gene:5711 PSMD5

dbSNP Gene:5711 PSMD5

ENSEMBL:ENSG00000095261 PSMD5

HGNC:9563 PSMD5

KEGG:hsa:5711 PSMD5

Monarch:5711 PSMD5

NCBI Gene:5711 PSMD5

OMIM:604452 PSMD5

UCSC:Q16401 PSMD5

Reference Transcript

Other Identifiers

11739153_a_at

11757947_s_at

17097895

203447_PM_at

203447_at

3223647

3223648

3223649

3223650

3223651

3223652

3223656

3223657

3223658

3223660

3223661

3223662

3223664

3223666

3223667

3223668

3223669

3223671

3223672

3223673

32240_at

5711

8163795

A_23_P43434

A_24_P363802

A_33_P3305243

A_33_P3305250

A_33_P3305254

D31889_at

GE62823

GE79767

GO:0000502

GO:0005515

GO:0005654

GO:0005829

GO:0008540

GO:0022624

GO:0043248

GO:0065003

GO:0070682

HMNXSV003002570

HMNXSV003054739

Hs.193725.0.S2_3p_at

ILMN_1720926

PH_hs_0032096

S79862_s_at

TC09001539.hg

Participates

as an input of

PSMD5 and PSMD2 bind PSMC2:PSMC1 (Homo sapiens)

as an output of

as a component of

PSMD5:PSMC2:PSMC1:PSMD2 [cytosol] (Homo sapiens)

Inferred To

Psmd5 [cytosol] (Mus musculus)

Psmd5 [cytosol] (Rattus norvegicus)

PSMD5 [cytosol] (Bos taurus)

PSMD5 [cytosol] (Caenorhabditis elegans)

PSMD5 [cytosol] (Dictyostelium discoideum)

PSMD5 [cytosol] (Drosophila melanogaster)

PSMD5 [cytosol] (Gallus gallus)

PSMD5 [cytosol] (Schizosaccharomyces pombe)

PSMD5 [cytosol] (Sus scrofa)

Ghost homologue of PSMD5 [cytosol] (Danio rerio)

Ghost homologue of PSMD5 [cytosol] (Plasmodium falciparum)

Ghost homologue of PSMD5 [cytosol] (Saccharomyces cerevisiae)

Ghost homologue of PSMD5 [cytosol] (Xenopus tropicalis)

LOC610717 [cytosol] (Canis familiaris)

Cross References

OpenTargets

ENSG00000095261

ENSEMBL

ENSP00000210313, ENST00000210313, ENSP00000363011, ENSG00000095261, ENST00000373904

HPA

ENSG00000095261-PSMD5

GeneCards

PSMD5

PRO

Q16401

Pharos - Targets

Q16401

GlyGen

Q16401

Interactors (27)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P35998 PSMC2	5	PSMC2 [cytosol] (R-HSA-68771) PSMC2 [nucleoplasm] (R-HSA-174332) PSMC2 [ficolin-1-rich granule lumen] (R-HSA-6800421) PSMC2 [extracellular region] (R-HSA-6806472) PSMC2 [secretory granule lumen] (R-HSA-6800994)	0.96	25
UniProt:P62191 PSMC1	2	PSMC1 [cytosol] (R-HSA-68768) PSMC1 [nucleoplasm] (R-HSA-174338)	0.939	14
UniProt:P55036 PSMD4	1	PSMD4 [cytosol] (R-HSA-68800)	0.643	4
UniProt:O43242 PSMD3	5	PSMD3 [cytosol] (R-HSA-68798) PSMD3 [nucleoplasm] (R-HSA-174328) PSMD3 [ficolin-1-rich granule lumen] (R-HSA-6800408) PSMD3 [extracellular region] (R-HSA-6806443) PSMD3 [secretory granule lumen] (R-HSA-6800873)	0.643	4
UniProt:Q15008 PSMD6	5	PSMD6 [cytosol] (R-HSA-68804) PSMD6 [nucleoplasm] (R-HSA-174316) PSMD6 [ficolin-1-rich granule lumen] (R-HSA-6800440) PSMD6 [extracellular region] (R-HSA-6806486) PSMD6 [secretory granule lumen] (R-HSA-6801036)	0.643	3
UniProt:Q13200 PSMD2	5	PSMD2 [cytosol] (R-HSA-68796) PSMD2 [nucleoplasm] (R-HSA-174311) PSMD2 [ficolin-1-rich granule lumen] (R-HSA-6800435) PSMD2 [extracellular region] (R-HSA-6806479) PSMD2 [secretory granule lumen] (R-HSA-6800919)	0.643	5
UniProt:P62195 PSMC5	2	PSMC5 [cytosol] (R-HSA-68780) PSMC5 [nucleoplasm] (R-HSA-174312)	0.643	4
UniProt:P62333 PSMC6	2	PSMC6 [cytosol] (R-HSA-68783) PSMC6 [nucleoplasm] (R-HSA-174319)	0.643	4
UniProt:Q16186 ADRM1	2	ADRM1 [cytosol] (R-HSA-5665939) ADRM1 [nucleoplasm] (R-HSA-9918361)	0.643	4
UniProt:P17980 PSMC3	5	PSMC3 [cytosol] (R-HSA-68774) PSMC3 [nucleoplasm] (R-HSA-174313) PSMC3 [ficolin-1-rich granule lumen] (R-HSA-6800429) PSMC3 [extracellular region] (R-HSA-6806496) PSMC3 [secretory granule lumen] (R-HSA-6800917)	0.643	4
UniProt:P48556 PSMD8	2	PSMD8 [cytosol] (R-HSA-68808) PSMD8 [nucleoplasm] (R-HSA-174318)	0.643	4
UniProt:P51665 PSMD7	5	PSMD7 [cytosol] (R-HSA-68806) PSMD7 [nucleoplasm] (R-HSA-174309) PSMD7 [ficolin-1-rich granule lumen] (R-HSA-6800406) PSMD7 [extracellular region] (R-HSA-6806488) PSMD7 [secretory granule lumen] (R-HSA-6801008)	0.643	4
UniProt:O00232 PSMD12	5	PSMD12 [cytosol] (R-HSA-68792) PSMD12 [nucleoplasm] (R-HSA-174339) PSMD12 [ficolin-1-rich granule lumen] (R-HSA-6800416) PSMD12 [extracellular region] (R-HSA-6806480) PSMD12 [secretory granule lumen] (R-HSA-6800934)	0.643	4
UniProt:P49821 NDUFV1	1	NDUFV1 [mitochondrial inner membrane] (R-HSA-163926)	0.556	3
UniProt:Q9BX70 BTBD2			0.556	3
UniProt:P33299	4	PSMC2 [cytosol] (R-SCE-68771) PSMC2 [ficolin-1-rich granule lumen] (R-SCE-6800421) PSMC2 [extracellular region] (R-SCE-6806472) PSMC2 [secretory granule lumen] (R-SCE-6800994)	0.556	3
UniProt:Q12800 TFCP2			0.556	3
UniProt:Q9H0C5 BTBD1	1	BTBD1 [cytosol] (R-HSA-8851650)	0.556	3
UniProt:Q8WTX7 GATSL3	1	CASTOR1 [cytosol] (R-HSA-9640228)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P43686 PSMC4	2	PSMC4 [cytosol] (R-HSA-68777) PSMC4 [nucleoplasm] (R-HSA-174315)	0.527	3
UniProt:Q9UNM6 PSMD13	5	PSMD13 [cytosol] (R-HSA-68794) PSMD13 [nucleoplasm] (R-HSA-174326) PSMD13 [ficolin-1-rich granule lumen] (R-HSA-6800413) PSMD13 [extracellular region] (R-HSA-6806469) PSMD13 [secretory granule lumen] (R-HSA-6800983)	0.527	3
UniProt:O00487 PSMD14	5	PSMD14 [cytosol] (R-HSA-68722) PSMD14 [nucleoplasm] (R-HSA-174329) PSMD14 [ficolin-1-rich granule lumen] (R-HSA-6800419) PSMD14 [extracellular region] (R-HSA-6806511) PSMD14 [secretory granule lumen] (R-HSA-6800926)	0.527	2
UniProt:Q99460 PSMD1	4	PSMD1 [cytosol] (R-HSA-68786) PSMD1 [nucleoplasm] (R-HSA-174348) PSMD1 [azurophil granule lumen] (R-HSA-6798741) PSMD1 [extracellular region] (R-HSA-6806194)	0.527	3
UniProt:O75832 PSMD10	1	PSMD10 [cytosol] (R-HSA-68788)	0.527	3
UniProt:O00231 PSMD11	5	PSMD11 [cytosol] (R-HSA-68790) PSMD11 [nucleoplasm] (R-HSA-174327) PSMD11 [ficolin-1-rich granule lumen] (R-HSA-6800436) PSMD11 [extracellular region] (R-HSA-6806441) PSMD11 [secretory granule lumen] (R-HSA-6800943)	0.527	3
UniProt:Q8N448 LNX2			0.488	2

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