Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]

Stable Identifier
R-HSA-1911505
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi membrane
Synonyms
Sialylated FRINGE-modified NOTCH2 receptor precursor
Icon
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] icon
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q04721 NOTCH2
Gene Names
NOTCH2
Chain
signal peptide:1-25, chain:26-2471, chain:1666-2471, chain:1697-2471
Reference Genes
BioGPS Gene:4853 NOTCH2
COSMIC (genes):NOTCH2 NOTCH2
CTD Gene:4853 NOTCH2
dbSNP Gene:4853 NOTCH2
ENSEMBL:ENSG00000134250 NOTCH2
ENSEMBL_homo_sapiens_GENE:ENSG00000134250.21 NOTCH2
HGNC:7882 NOTCH2
KEGG Gene (Homo sapiens):4853 NOTCH2
Monarch:4853 NOTCH2
NCBI Gene:4853 NOTCH2
OMIM:600275 NOTCH2
UCSC:Q04721 NOTCH2
Reference Transcript
Other Identifiers
11719213_s_at
11732189_at
11732190_at
11745417_a_at
11745768_a_at
11745769_a_at
11752984_s_at
16691668
202443_PM_x_at
202443_x_at
202445_PM_s_at
202445_s_at
210756_PM_s_at
210756_s_at
212377_PM_s_at
212377_s_at
227067_PM_x_at
227067_x_at
2355658
2355661
2355662
2355665
2355667
2355668
2431114
2431115
2431116
2431117
2431118
2431119
2431120
2431121
2431123
2431124
2431125
2431127
2431128
2431129
2431130
2431131
2431133
2431135
2431136
2431137
2431139
2431140
2431141
2431143
2431144
2431150
2431151
2431152
2431153
2431155
2431156
2431157
2431158
2431159
2431160
2431162
2431169
2431174
2431180
2431201
2431202
2431203
2431237
2431239
38083_at
48486_at
4853
65285_r_at
7919095
A_23_P200792
A_33_P3258824
GE56584
GE61736
GO:0000122
GO:0000139
GO:0000987
GO:0001228
GO:0001701
GO:0001709
GO:0001889
GO:0001890
GO:0001947
GO:0002011
GO:0002315
GO:0002376
GO:0002437
GO:0003162
GO:0003184
GO:0003677
GO:0005509
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005794
GO:0005886
GO:0005929
GO:0006351
GO:0006355
GO:0006357
GO:0006915
GO:0006954
GO:0006959
GO:0007219
GO:0007275
GO:0007368
GO:0007399
GO:0007411
GO:0008283
GO:0008284
GO:0009887
GO:0009986
GO:0010629
GO:0010838
GO:0012501
GO:0016020
GO:0019899
GO:0023052
GO:0030097
GO:0030154
GO:0030326
GO:0030509
GO:0030513
GO:0035264
GO:0035556
GO:0035622
GO:0038023
GO:0042060
GO:0042742
GO:0043011
GO:0043065
GO:0043066
GO:0043226
GO:0043235
GO:0045672
GO:0045944
GO:0046579
GO:0046849
GO:0048856
GO:0050793
GO:0051059
GO:0051152
GO:0060089
GO:0060413
GO:0060674
GO:0061073
GO:0070374
GO:0070986
GO:0071228
GO:0072014
GO:0072015
GO:0072104
GO:0072574
GO:0072576
GO:0098542
GO:0140110
GO:1902895
GO:1990705
GO:2001204
HMNXSV003002044
HMNXSV003044517
HMNXSV003048364
Hs.8121.2.A1_3p_a_at
Hs.8121.3.A1_3p_a_at
ILMN_1656254
ILMN_1777845
ILMN_2405297
PH_hs_0000871
TC01003054.hg
TC01005750.hg
g11275977_3p_a_at
g13249343_3p_a_at
p375
Participates
as a candidate of
Other forms of this molecule
NOTCH2(1582-1665) [extracellular region]
NOTCH2(1666-1696) [plasma membrane]
NEXT2 [plasma membrane]
NICD2 [cytosol]
NICD2 [nucleoplasm]
Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane]
FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane]
Pre-NOTCH2 [endoplasmic reticulum membrane]
18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane]
NOTCH2(1582-2471) [plasma membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region]
NOTCH2(1582-2471) [Golgi membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane]
Inferred To
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (Gallus gallus)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (Xenopus tropicalis)
Modified Residues
Name
O-fucosyl-L-threonine at 78
Coordinate
78
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 120
Coordinate
120
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 158
Coordinate
158
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 197
Coordinate
197
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 235
Coordinate
235
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 314
Coordinate
314
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 352
Coordinate
352
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 470
Coordinate
470
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 696
Coordinate
696
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 771
Coordinate
771
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 809
Coordinate
809
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-serine at 925
Coordinate
925
PsiMod Name
O-fucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to an O-fucosylserine.
Name
O-fucosyl-L-threonine at 963
Coordinate
963
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 1001
Coordinate
1001
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 1039
Coordinate
1039
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 1077
Coordinate
1077
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 1163
Coordinate
1163
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 1201
Coordinate
1201
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-fucosyl-L-threonine at 1318
Coordinate
1318
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Name
O-glucosyl-L-serine at 150
Coordinate
150
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 381
Coordinate
381
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 462
Coordinate
462
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 500
Coordinate
500
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 538
Coordinate
538
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 613
Coordinate
613
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 651
Coordinate
651
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 688
Coordinate
688
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 726
Coordinate
726
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 763
Coordinate
763
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 801
Coordinate
801
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 879
Coordinate
879
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 955
Coordinate
955
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 1031
Coordinate
1031
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 1155
Coordinate
1155
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-glucosyl-L-serine at 1270
Coordinate
1270
PsiMod Name
O-glucosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-beta-glucosylated L-serine.
Name
O-fucosyl-L-threonine (alpha- N- acetylneuraminyl- (2?3)- beta- D- galactopyranosyl- (1?4)- 2- acetamido- 2- deoxy- ?- D- glucopyranosyl- (1?3)- 6- deoxy- alpha- L- galactopyranosyl group) at unknown position
Modification
alpha- N- acetylneuraminyl- (2?3)- beta- D- galactopyranosyl- (1?4)- 2- acetamido- 2- deoxy- ?- D- glucopyranosyl- (1?3)- 6- deoxy- alpha- L- galactopyranosyl group
PsiMod Name
O-fucosyl-L-threonine
PsiMod Definition
A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
GeneCards
HPA
Ensembl
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
Interactors (7)
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