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PXDN [extracellular region]
Stable Identifier
R-HSA-2559628
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Peroxidasin
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in extracellular matrix, focal adhesion and epithelial-to-mesenchymal transition (Homo sapiens)
MITF-M-dependent PXDN gene expression (Homo sapiens)
PXDN [extracellular region] (Homo sapiens)
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Crosslinking of collagen fibrils (Homo sapiens)
Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)
PXDN:Br- [extracellular region] (Homo sapiens)
PXDN [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92626 PXDN
Gene Names
PXDN, KIAA0230, MG50, PRG2, PXD01, VPO, VPO1
Chain
signal peptide:1-26, chain:27-1479, chain:27-1336
Reference Genes
BioGPS Gene:7837 PXDN
COSMIC (genes):PRG2 PXDN
COSMIC (genes):PXDN PXDN
CTD Gene:7837 PXDN
dbSNP Gene:7837 PXDN
ENSEMBL:ENSG00000130508 PXDN
HGNC:14966 PXDN
Monarch:7837 PXDN
NCBI Gene:7837 PXDN
OMIM:605158 PXDN
UCSC:Q92626 PXDN
Reference Transcript
RefSeq:NM_012293.2 PXDN
Other Identifiers
11716086_a_at
11754993_s_at
16893846
212012_PM_at
212012_at
212013_PM_at
212013_at
2467067
2467068
2467069
2467086
2467087
2467088
2467090
2467091
2467094
2467095
2467096
2467097
2467099
2467103
2467108
2467109
2467110
2467111
2467114
2467116
2467117
2467120
2467122
2467123
2467124
2467127
2467129
2467130
2467131
2467132
2467133
2467134
2467137
2467138
2467139
2467140
2467141
2467142
2467143
2467144
2467145
2467146
2467147
39327_at
65963_at
7837
8050007
A_23_P257144
A_33_P3238166
A_33_P3271455
D86983_at
GE57381
GO:0001525
GO:0001654
GO:0001960
GO:0002376
GO:0003824
GO:0004601
GO:0005152
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005604
GO:0005615
GO:0005783
GO:0006955
GO:0006979
GO:0007155
GO:0009986
GO:0016209
GO:0016491
GO:0016684
GO:0020037
GO:0030198
GO:0030199
GO:0030312
GO:0031012
GO:0042744
GO:0043226
GO:0043237
GO:0046872
GO:0048856
GO:0051260
GO:0062023
GO:0065003
GO:0070062
GO:0070207
GO:0070831
GO:0071711
GO:0098754
GO:0098772
GO:0098869
GO:0140825
HMNXSV003055551
Hs.118893.0.S1_3p_at
Hs.118893.0.S2_3p_at
ILMN_2363658
PH_hs_0006559
TC02001512.hg
Participates
as a component of
PXDN:Br- [extracellular region] (Homo sapiens)
as an output of
MITF-M-dependent PXDN gene expression (Homo sapiens)
Inferred To
PXDN [extracellular region]
(Bos taurus)
PXDN [extracellular region]
(Canis familiaris)
PXDN [extracellular region]
(Gallus gallus)
PXDN [extracellular region]
(Mus musculus)
PXDN [extracellular region]
(Rattus norvegicus)
PXDN [extracellular region]
(Sus scrofa)
PXDN [extracellular region]
(Xenopus tropicalis)
Cross References
ENSEMBL
ENST00000252804
,
ENSP00000252804
OpenTargets
ENSG00000130508
HPA
ENSG00000130508-PXDN
PRO
Q92626
Pharos - Targets
Q92626
GlyGen
Q92626
Orphanet
PXDN
HMDB Protein
HMDBP07959
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q08830 FGL1
0.527
2
UniProt:Q9BS26 ERP44
2
ERP44 [extracellular region]
(R-HSA-6806302)
ERP44 [specific granule lumen]
(R-HSA-6799567)
0.527
2
UniProt:Q03405 PLAUR
7
PLAUR [endoplasmic reticulum membrane]
(R-HSA-162703)
GPI-PLAUR [endoplasmic reticulum membrane]
(R-HSA-162687)
PLAUR(306-335) [endoplasmic reticulum lumen]
(R-HSA-162707)
PLAUR(23-335) [endoplasmic reticulum membrane]
(R-HSA-162866)
GPI-PLAUR [plasma membrane]
(R-HSA-158946)
PLAUR [plasma membrane]
(R-HSA-6806165)
GPI-PLAUR [specific granule membrane]
(R-HSA-6806143)
0.527
2
UniProt:P59665 DEFA1
9
DEFA1(20-94) [Golgi lumen]
(R-HSA-1467282)
DEFA1(66-94) [Golgi lumen]
(R-HSA-975663)
DEFA1(20-65) [Golgi lumen]
(R-HSA-8864970)
DEFA1(1-94) [Golgi lumen]
(R-HSA-1467215)
DEFA1(66-94) [extracellular region]
(R-HSA-1461998)
DEFA1(66-94) [azurophil granule lumen]
(R-HSA-1470038)
DEFA1(65-94) [extracellular region]
(R-HSA-1462022)
omega-N-(ADP-ribosyl)-L-arginine-DEFA1(65-94) [extracellular region]
(R-HSA-1972397)
DEFA1(65-94) [azurophil granule lumen]
(R-HSA-1470053)
0.527
2
UniProt:Q9NRD1 FBXO6
1
FBXO6 [cytosol]
(R-HSA-391296)
0.527
2
UniProt:Q99435 NELL2
1
NELL2 [extracellular region]
(R-HSA-9010198)
0.527
2
UniProt:Q96CS2 HAUS1
1
HAUS1 [cytosol]
(R-HSA-8855199)
0.527
2
UniProt:Q9BT09 CNPY3
1
CNPY3 [endoplasmic reticulum lumen]
(R-HSA-1678932)
0.527
2
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