Reactome | ANKRD28 [cytosol]

ANKRD28 [cytosol]

Stable Identifier

R-HSA-5685714

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        PP6 dephosphorylates SEC24 (Homo sapiens)
        
        PP6 [cytosol] (Homo sapiens)
        
        ANKRD28 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:O15084 ANKRD28

Gene Names

ANKRD28, KIAA0379

Chain

chain:1-1053

Reference Genes

BioGPS Gene:23243 ANKRD28

COSMIC (genes):ANKRD28 ANKRD28

CTD Gene:23243 ANKRD28

dbSNP Gene:23243 ANKRD28

ENSEMBL:ENSG00000206560 ANKRD28

HGNC:29024 ANKRD28

KEGG:hsa:23243 ANKRD28

Monarch:23243 ANKRD28

NCBI Gene:23243 ANKRD28

OMIM:611122 ANKRD28

UCSC:O15084 ANKRD28

Reference Transcript

Other Identifiers

11722637_a_at

11722638_at

11748347_a_at

11752240_a_at

16951247

213035_PM_at

213035_at

226025_PM_at

226025_at

229307_PM_at

229307_at

23243

2664453

2664454

2664455

2664456

2664457

2664458

2664459

2664461

2664462

2664463

2664464

2664465

2664466

2664467

2664468

2664469

2664471

2664472

2664473

2664474

2664475

2664476

2664478

2664480

2664481

2664482

2664483

2664484

2664485

2664487

2664489

2664490

2664491

2664493

2664494

2664496

2664497

2664498

2664501

2664506

2664507

2664510

2664511

2664516

2664518

2664522

2664523

2664524

2664525

2664526

2664527

2664528

2664529

2664530

2664531

2664536

2664540

2664541

2664542

2664543

35655_at

62174_at

71544_at

8085628

A_23_P109794

A_24_P217365

GE53095

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0043226

HMNXSV003004147

HMNXSV003004343

HMNXSV003055797

Hs.159971.1.S1_3p_at

Hs.32556.0.S1_3p_at

ILMN_1697594

ILMN_2232520

PH_hs_0039329

TC03001213.hg

Participates

as a component of

PP6 [cytosol] (Homo sapiens)

Other forms of this molecule

ANKRD28 [nucleoplasm]

Inferred To

Ankrd28 [cytosol] (Mus musculus)

Ankrd28 [cytosol] (Rattus norvegicus)

ANKRD28 [cytosol] (Bos taurus)

ANKRD28 [cytosol] (Canis familiaris)

ANKRD28 [cytosol] (Gallus gallus)

ANKRD28 [cytosol] (Sus scrofa)

PHO81 [cytosol] (Saccharomyces cerevisiae)

ankrd28 [cytosol] (Xenopus tropicalis)

HOS4 [cytosol] (Saccharomyces cerevisiae)

Homologues of ANKRD28 [cytosol] (Saccharomyces cerevisiae)

cnrM [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001182028.1, XP_005265053.1, XP_016861516.1, NP_001336206.1, XP_054201850.1, NP_001336207.1, XP_047303769.1, NP_001336212.1, NP_056014.2, XP_016861515.1, NP_001182027.1, XP_011531842.1

OpenTargets

ENSG00000206560

ENSEMBL

ENSG00000206560, ENST00000399451, ENST00000683139, ENSP00000397341, ENSP00000508086, ENST00000624145, ENSP00000485421, ENSP00000382379, ENST00000412318

HPA

ENSG00000206560-ANKRD28

GeneCards

ANKRD28

PRO

O15084

Pharos - Targets

O15084

GlyGen

O15084

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53350 PLK1	4	PLK1 [cytosol] (R-HSA-164603) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) p-T210-PLK1 [cytosol] (R-HSA-3000318) PLK1 [nucleoplasm] (R-HSA-156720)	0.643	3
UniProt:Q96CW1 AP2M1	6	AP2M1 [plasma membrane] (R-HSA-167585) AP2M1 [lysosomal membrane] (R-HSA-196144) AP2M1 [cytosol] (R-HSA-182227) AP2M1 [clathrin-coated endocytic vesicle membrane] (R-HSA-2130423) AP2M1 [endolysosome membrane] (R-HSA-6784828) p-T156 AP2M1 [cytosol] (R-HSA-8856805)	0.643	3
UniProt:Q14694 USP10	3	USP10 [nucleoplasm] (R-HSA-3222218) K63polyUb-USP10 [cytosol] (R-HSA-6782986) USP10 [cytosol] (R-HSA-6782974)	0.615	4
UniProt:Q96MU7 YTHDC1	1	YTHDC1 [nucleoplasm] (R-HSA-9935812)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.527	3
UniProt:Q04721 NOTCH2	18	NOTCH2(1582-1665) [extracellular region] (R-HSA-157652) NOTCH2(1666-1696) [plasma membrane] (R-HSA-157628) NEXT2 [plasma membrane] (R-HSA-157225) NICD2 [cytosol] (R-HSA-157642) NICD2 [nucleoplasm] (R-HSA-157942) Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911428) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911417) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911505) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane] (R-HSA-1983676) NOTCH2(1582-2471) [Golgi membrane] (R-HSA-157017) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region] (R-HSA-1983678) NOTCH2(1582-2471) [plasma membrane] (R-HSA-157228) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane] (R-HSA-1472874) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467379) 18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467363) Pre-NOTCH2 [endoplasmic reticulum membrane] (R-HSA-157025) FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane] (R-HSA-1911520) FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane] (R-HSA-1911518)	0.519	2

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