Pre-NOTCH2 [endoplasmic reticulum membrane]

Stable Identifier
R-HSA-157025
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
NOTCH2(26-2471), NOTCH2, Notch 2 receptor precursor
Icon
Pre-NOTCH2 [endoplasmic reticulum membrane] icon
Pre-NOTCH2 [endoplasmic reticulum membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q04721 NOTCH2
Gene Names
NOTCH2
Chain
signal peptide:1-25, chain:26-2471, chain:1666-2471, chain:1697-2471
Reference Genes
BioGPS Gene:4853 NOTCH2
COSMIC (genes):NOTCH2 NOTCH2
CTD Gene:4853 NOTCH2
dbSNP Gene:4853 NOTCH2
ENSEMBL:ENSG00000134250 NOTCH2
HGNC:7882 NOTCH2
KEGG:hsa:4853 NOTCH2
Monarch:4853 NOTCH2
NCBI Gene:4853 NOTCH2
OMIM:600275 NOTCH2
UCSC:Q04721 NOTCH2
Reference Transcript
Other Identifiers
11719212_a_at
11719213_s_at
11732189_at
11732190_at
11745417_a_at
11745768_a_at
11745769_a_at
11752984_s_at
16691668
16691718
202443_PM_x_at
202443_x_at
202445_PM_s_at
202445_s_at
210756_PM_s_at
210756_s_at
212377_PM_s_at
212377_s_at
227067_PM_x_at
227067_x_at
233951_PM_at
233951_at
2355649
2355658
2355661
2355662
2355663
2355665
2355667
2355668
2355669
2355670
2355671
2355672
2355673
2431114
2431115
2431116
2431117
2431118
2431119
2431120
2431121
2431123
2431124
2431125
2431126
2431127
2431128
2431129
2431130
2431131
2431133
2431134
2431135
2431136
2431137
2431139
2431140
2431141
2431143
2431144
2431145
2431146
2431147
2431148
2431149
2431150
2431151
2431152
2431153
2431155
2431156
2431157
2431158
2431159
2431160
2431162
2431163
2431167
2431168
2431169
2431173
2431174
2431179
2431180
2431186
2431201
2431202
2431203
2431204
2431237
2431239
2431259
38083_at
48486_at
4853
65285_r_at
7904702
7919095
A_21_P0001575
A_23_P200792
A_24_P50057
A_32_P5040
A_33_P3212645
A_33_P3258824
GE56584
GE61736
GO:0000122
GO:0000139
GO:0000987
GO:0001228
GO:0001701
GO:0001709
GO:0001889
GO:0001890
GO:0001947
GO:0002011
GO:0002315
GO:0002376
GO:0002437
GO:0003162
GO:0003184
GO:0003677
GO:0005509
GO:0005515
GO:0005576
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005886
GO:0005929
GO:0006355
GO:0006357
GO:0006915
GO:0006954
GO:0006959
GO:0007219
GO:0007275
GO:0007368
GO:0007399
GO:0007411
GO:0008283
GO:0008284
GO:0009887
GO:0009986
GO:0010629
GO:0010838
GO:0012501
GO:0016020
GO:0019899
GO:0030097
GO:0030154
GO:0030326
GO:0030509
GO:0030513
GO:0035264
GO:0035556
GO:0035622
GO:0038023
GO:0042060
GO:0042742
GO:0043011
GO:0043065
GO:0043066
GO:0043226
GO:0043235
GO:0045672
GO:0045944
GO:0046579
GO:0046849
GO:0048856
GO:0050793
GO:0051059
GO:0051152
GO:0060089
GO:0060413
GO:0060674
GO:0061073
GO:0070374
GO:0070986
GO:0071228
GO:0072014
GO:0072015
GO:0072104
GO:0072574
GO:0072576
GO:0098542
GO:0140110
GO:1902895
GO:1990705
GO:2001204
HMNXSV003002044
HMNXSV003029187
HMNXSV003044517
HMNXSV003048364
HMNXSV003049984
Hs.135721.0.A1_3p_at
Hs.8121.2.A1_3p_a_at
Hs.8121.3.A1_3p_a_at
ILMN_1656254
ILMN_1685445
ILMN_1747730
ILMN_1777758
ILMN_1777845
ILMN_2405297
PH_hs_0000871
PH_hs_0036012
TC01003054.hg
TC01005750.hg
TC01005751.hg
g11275977_3p_a_at
g13249343_3p_a_at
p17486
p375
Participates
as an output of
as a member of
Other forms of this molecule
NOTCH2(1582-1665) [extracellular region]
NOTCH2(1666-1696) [plasma membrane]
NEXT2 [plasma membrane]
NICD2 [cytosol]
NICD2 [nucleoplasm]
Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane]
NOTCH2(1582-2471) [Golgi membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region]
NOTCH2(1582-2471) [plasma membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane]
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane]
FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane]
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
HPA
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (7)
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