Reactome | INHBE [extracellular region]

INHBE [extracellular region]

Stable Identifier

R-HSA-1449700

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Inhibin beta E chain, INHBE_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P58166 INHBE

Gene Names

INHBE

Chain

signal peptide:1-19, propeptide:20-236, chain:237-350

Reference Genes

BioGPS Gene:83729 INHBE

COSMIC (genes):INHBE INHBE

CTD Gene:83729 INHBE

dbSNP Gene:83729 INHBE

ENSEMBL:ENSG00000139269 INHBE

HGNC:24029 INHBE

KEGG:hsa:83729 INHBE

Monarch:83729 INHBE

NCBI Entrez Gene:83729 INHBE

OMIM:612031 INHBE

UCSC:P58166 INHBE

Reference Transcript

RefSeq:NM_031479.5 INHBE

Other Identifiers

11736262_at

16752877

210587_PM_at

210587_at

3418112

3418113

3418114

3418115

3418116

3418117

3418119

3418121

7956426

83729

A_14_P129792

A_24_P141707

GE79817

GO:0005125

GO:0005179

GO:0005576

GO:0005615

GO:0007178

GO:0008083

GO:0030312

GO:0031012

GO:0032924

GO:0048018

GO:0098772

GO:1904178

HMNXSV003043838

ILMN_1811767

PH_hs_0029592

PH_hs_0032455

TC12000529.hg

g13477368_3p_at

Participates

as a component of

INHBE dimer [extracellular region] (Homo sapiens)

as a member of

INHBs [extracellular region] (Homo sapiens)

Inferred To

INHBE [extracellular region] (Bos taurus)

INHBE [extracellular region] (Canis familiaris)

INHBE [extracellular region] (Gallus gallus)

INHBE [extracellular region] (Sus scrofa)

inhbc.2 [extracellular region] (Xenopus tropicalis)

Inhbe [extracellular region] (Mus musculus)

Inhbe [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_113667.1

ENSEMBL

ENSG00000139269, ENSP00000266646, ENST00000266646

OpenTargets

ENSG00000139269

GeneCards

INHBE

HPA

ENSG00000139269-INHBE

PRO

P58166

Pharos - Targets

P58166

GlyGen

P58166

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q04721 NOTCH2	18	NOTCH2(1582-1665) [extracellular region] (R-HSA-157652) NOTCH2(1666-1696) [plasma membrane] (R-HSA-157628) NEXT2 [plasma membrane] (R-HSA-157225) NICD2 [cytosol] (R-HSA-157642) NICD2 [nucleoplasm] (R-HSA-157942) Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911428) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911417) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane] (R-HSA-1911505) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane] (R-HSA-1983676) NOTCH2(1582-2471) [Golgi membrane] (R-HSA-157017) 18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region] (R-HSA-1983678) NOTCH2(1582-2471) [plasma membrane] (R-HSA-157228) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane] (R-HSA-1472874) 18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467379) 18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane] (R-HSA-1467363) Pre-NOTCH2 [endoplasmic reticulum membrane] (R-HSA-157025) FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane] (R-HSA-1911520) FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane] (R-HSA-1911518)	0.527	2
UniProt:Q96RT1 ERBIN	1	ERBIN [plasma membrane] (R-HSA-1358718)	0.527	2
UniProt:Q9Y2C2 UST	1	UST [Golgi membrane] (R-HSA-2022058)	0.527	2
UniProt:P11021 HSPA5	6	HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [extracellular region] (R-HSA-351322)	0.527	2
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.527	2

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