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RABGGTB [cytosol]
Stable Identifier
R-HSA-8870419
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Geranylgeranyl transferase type-2 subunit beta ecNumber2.5.1.60/ecNumber, PGTB2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
RAB geranylgeranylation (Homo sapiens)
FarC-PTP4A2 binds RABGGTB (Homo sapiens)
FarC-PTP4A2:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTA and RABGGTB bind (Homo sapiens)
FarC-PTP4A2:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT binds the RAB-binding subunit (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT geranylgeranylates RAB proteins (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT:CHMs:RABs:GDP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGTA:RGGTB:GGPP [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT:CHM binds RABs (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
RGGT:CHMs:RABs:GDP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB:CHMs:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
RABGGTB [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P53611 RABGGTB
Gene Names
RABGGTB, GGTB
Chain
initiator methionine:1, chain:2-331
Reference Genes
BioGPS Gene:5876 RABGGTB
COSMIC (genes):RABGGTB RABGGTB
CTD Gene:5876 RABGGTB
dbSNP Gene:5876 RABGGTB
ENSEMBL:ENSG00000137955 RABGGTB
HGNC:9796 RABGGTB
KEGG Gene (Homo sapiens):5876 RABGGTB
Monarch:5876 RABGGTB
NCBI Gene:5876 RABGGTB
OMIM:179080 RABGGTB
Reference Transcript
RefSeq:NM_004582.3 RABGGTB
Other Identifiers
0004280324
11724300_a_at
11757294_x_at
209180_at
209181_s_at
213704_at
2342633
2342637
2342638
2342639
2342640
2342644
2342649
2342650
2342652
2342656
2342658
2342659
2342660
2342662
37703_at
5876
781_at
7902382
A_14_P128168
A_23_P85371
A_24_P336705
A_33_P3311618
GO:0003674
GO:0003824
GO:0004659
GO:0004663
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005829
GO:0005886
GO:0005968
GO:0006464
GO:0007601
GO:0008150
GO:0008219
GO:0008270
GO:0016740
GO:0016765
GO:0018215
GO:0018342
GO:0018344
GO:0019899
GO:0031267
GO:0032991
GO:0042981
GO:0043167
GO:0043687
GO:0046872
GO:0050877
HMNXSV003013751
ILMN_2163796
PH_hs_0004556
X98001_at
g1216503_3p_a_at
Participates
as an input of
FarC-PTP4A2 binds RABGGTB (Homo sapiens)
RABGGTA and RABGGTB bind (Homo sapiens)
as a component of
FarC-PTP4A2:RABGGTB [cytosol] (Homo sapiens)
RGGTA:RGGTB:GGPP [cytosol] (Homo sapiens)
RABGGTA:RABGGTB [cytosol] (Homo sapiens)
Other forms of this molecule
RABGGTB [plasma membrane]
Inferred To
RABGGTB [cytosol]
(Canis familiaris)
RABGGTB [cytosol]
(Gallus gallus)
RABGGTB [cytosol]
(Plasmodium falciparum)
Rabggtb [cytosol]
(Mus musculus)
Rabggtb [cytosol]
(Rattus norvegicus)
RabGGTb [cytosol]
(Drosophila melanogaster)
ptb1 [cytosol]
(Schizosaccharomyces pombe)
ggtb-1 [cytosol]
(Caenorhabditis elegans)
Ghost homologue of RABGGTB [cytosol]
(Bos taurus)
Ghost homologue of RABGGTB [cytosol]
(Sus scrofa)
rabggtb [cytosol]
(Danio rerio)
rabggtb [cytosol]
(Dictyostelium discoideum)
rabggtb [cytosol]
(Xenopus tropicalis)
BET2 [cytosol]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_004573.2
OpenTargets
ENSG00000137955
IntEnz
2.5.1.60
HPA
ENSG00000137955-RABGGTB
GeneCards
P53611
Ensembl
ENSG00000137955
,
ENST00000319942
,
ENSP00000317473
PRO
P53611
Pharos - Targets
P53611
GlyGen
P53611
HMDB Protein
HMDBP11879
PDB
6J6X
,
6J7F
,
6J7X
,
6J74
,
6O60
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P57081 WDR4
1
WDR4 [nucleoplasm]
(R-HSA-6782341)
0.718
6
UniProt:Q9UBV7 B4GALT7
4
B4GALT7 A186D [Golgi membrane]
(R-HSA-3621785)
B4GALT7 L206P [Golgi membrane]
(R-HSA-3621790)
B4GALT7 R270C [Golgi membrane]
(R-HSA-3621734)
B4GALT7 [Golgi membrane]
(R-HSA-1889950)
0.718
6
UniProt:Q92696 RABGGTA
2
RABGGTA [cytosol]
(R-HSA-8870418)
RABGGTA [plasma membrane]
(R-HSA-6801086)
0.666
4
UniProt:P20339 RAB5A
6
GGC-RAB5A [clathrin-coated endocytic vesicle membrane]
(R-HSA-8871125)
RAB5A [cytosol]
(R-HSA-2201187)
RAB5A [endosome membrane]
(R-HSA-452257)
RAB5A [early endosome membrane]
(R-HSA-2130175)
GGC-RAB5A [cytosol]
(R-HSA-8870432)
GGC-RAB5A [early endosome membrane]
(R-HSA-8875323)
0.569
3
UniProt:Q86YD3 TMM25
0.556
3
UniProt:Q7Z5A9 TAFA1
0.556
3
UniProt:P24592 IGFBP6
1
IGFBP6 [extracellular region]
(R-HSA-381475)
0.556
3
UniProt:Q96AX2 RAB37
5
GGC-RAB37 [cytosol]
(R-HSA-8873996)
RAB37 [cytosol]
(R-HSA-8873678)
RAB37 [azurophil granule membrane]
(R-HSA-6799607)
RAB37 [plasma membrane]
(R-HSA-6799686)
RAB37 [specific granule membrane]
(R-HSA-6799605)
0.488
2
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