Reactome | p-LTBP1 [endoplasmic reticulum lumen]

p-LTBP1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8957050

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

LTBP1, Latent-transforming growth factor beta-binding protein 1, LTBP1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14766 LTBP1

Gene Names

LTBP1

Chain

signal peptide:1-23, chain:24-1721

Reference Genes

BioGPS Gene:4052 LTBP1

COSMIC (genes):LTBP1 LTBP1

CTD Gene:4052 LTBP1

dbSNP Gene:4052 LTBP1

ENSEMBL:ENSG00000049323 LTBP1

ENSEMBL_homo_sapiens_GENE:ENSG00000049323.16 LTBP1

HGNC:6714 LTBP1

KEGG Gene (Homo sapiens):4052 LTBP1

Monarch:4052 LTBP1

NCBI Gene:4052 LTBP1

OMIM:150390 LTBP1

UCSC:Q14766 LTBP1

Reference Transcript

Other Identifiers

11728718_a_at

11728719_a_at

11741263_s_at

11741264_x_at

11746004_a_at

1495_at

16878947

202728_PM_s_at

202728_s_at

202729_PM_s_at

202729_s_at

2476512

2476513

2476514

2476515

2476516

2476517

2476518

2476519

2476522

2476536

2476552

2476565

2476566

2476567

2476580

2476582

2476592

2476594

2476597

2476598

2476600

2476601

2476602

2476603

2476604

2476605

2476606

2476608

2476609

2476612

2476616

2476619

2476621

2476623

2476624

2476638

2476639

2476643

2476644

2476645

2476646

2476647

2476656

2476658

2476659

2476660

2476661

2476662

2476663

2476664

4052

8041383

A_14_P103270

A_14_P118628

A_23_P43810

A_33_P3304655

GE61118

GO:0001527

GO:0003824

GO:0005024

GO:0005198

GO:0005201

GO:0005509

GO:0005515

GO:0005576

GO:0005783

GO:0005788

GO:0007178

GO:0016740

GO:0019838

GO:0023052

GO:0030312

GO:0031012

GO:0032991

GO:0035583

GO:0043226

GO:0050431

GO:0050436

GO:0060089

GO:0060090

GO:0062023

GO:0140096

GO:1901388

HMNXSV003026536

HMNXSV003026862

Hs.241257.0.S1_3p_a_at

ILMN_1656321

ILMN_1785402

M34057_at

PH_hs_0012930

TC02000219.hg

g4557730_3p_a_at

Participates

as a member of

FAM20C products [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

LTBP1 [endoplasmic reticulum lumen]

LTBP1 [extracellular region]

Inferred To

phospho-Ltbp1 [endoplasmic reticulum lumen] (Mus musculus)

phospho-Ltbp1 [endoplasmic reticulum lumen] (Rattus norvegicus)

phospho-p-LTBP1 [endoplasmic reticulum lumen] (Gallus gallus)

phospho-nid-1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)

phospho-LTBP1 [endoplasmic reticulum lumen] (Bos taurus)

phospho-LTBP1 [endoplasmic reticulum lumen] (Canis familiaris)

phospho-LTBP1 [endoplasmic reticulum lumen] (Sus scrofa)

phospho-ltbp1 [endoplasmic reticulum lumen] (Xenopus tropicalis)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_000618.3, NP_001159737.1, NP_996826.2, NP_001159736.1, XP_011531155.1, NP_001159738.1

OpenTargets

ENSG00000049323

HPA

ENSG00000049323-LTBP1

GeneCards

Q14766

Ensembl

ENSP00000385359, ENST00000404816, ENSG00000049323, ENST00000404525, ENST00000407925, ENSP00000386043, ENSP00000384091

PRO

Q14766

Pharos - Targets

Q14766

PDB

1KSQ

HMDB Protein

HMDBP14565

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06276 BCHE	2	BCHE [extracellular region] (R-HSA-434469) BCHE [plasma membrane] (R-HSA-3640835)	0.527	2
UniProt:P08254 MMP3	6	MMP3(55-99) [extracellular region] (R-HSA-1604687) MMP3(18-54) [extracellular region] (R-HSA-1604705) MMP3(55-477) [extracellular region] (R-HSA-1604735) MMP3(18-477) [extracellular region] (R-HSA-1604707) MMP3 [extracellular region] (R-HSA-8943665) MMP3(100-477) [extracellular region] (R-HSA-1430778)	0.527	2
UniProt:Q01523 DEFA5	5	DEFA5(1-94) [Golgi lumen] (R-HSA-1467267) DEFA5(20-94) [Golgi lumen] (R-HSA-1467208) DEFA5(20-94) [secretory granule lumen] (R-HSA-1471358) DEFA5(20-94) [extracellular region] (R-HSA-1471344) DEFA5(?-94) [extracellular region] (R-HSA-1462017)	0.527	2
UniProt:P09238 MMP10	2	MMP10 [extracellular region] (R-HSA-1442488) MMP10(18-476) [extracellular region] (R-HSA-1604748)	0.527	2