p-Y239,Y240,Y317-SHC1-2 [cytosol]

Stable Identifier
R-HSA-1433505
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-Y239,Y240,Y317-SHC1 p52, SHC-transforming protein 1, SHC1
Icon
p-Y239,Y240,Y317-SHC1-2 [cytosol] icon
p-Y239,Y240,Y317-SHC1-2 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P29353-2 SHC1
Gene Names
SHC1, SHC, SHCA
Participates
as a member of
as a candidate of
as an output of
as an input of
as a component of
Other forms of this molecule
p-Y239,Y240,Y317-SHC1-2 [plasma membrane]
p-Y317-SHC1-2 [cytosol]
SHC1-2 [cytosol]
p-S29,3Y-SHC1-2 [cytosol]
SHC1-2 [plasma membrane]
Inferred From
p-Y239,Y240,Y313-Shc1 [cytosol] (Mus musculus)
Inferred To
phospho-Shc1 [cytosol] (Mus musculus)
phospho-Shc1 [cytosol] (Rattus norvegicus)
phospho-SHC1 [cytosol] (Bos taurus)
phospho-SHC1 [cytosol] (Canis familiaris)
phospho-SHC1 [cytosol] (Gallus gallus)
phospho-SHC1 [cytosol] (Sus scrofa)
phospho-Shc [cytosol] (Drosophila melanogaster)
Ghost homologue of p-Y239,Y240,Y317-SHC1-2 [cytosol] (Xenopus tropicalis)
Modified Residues
Name
O4'-phospho-L-tyrosine at 239
Coordinate
239
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 240
Coordinate
240
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 317
Coordinate
317
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
OpenTargets
ENSEMBL
HPA
GeneCards
ZINC - Substances
ZINC target
PRO
Pharos - Targets
GlyGen
ZINC - Predictions - Purchasable
PDB
Interactors (40)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62993 GRB2  1 0.976 33
 UniProt:P00533 EGFR  20 0.976 44
 UniProt:Q05209 PTPN12  2 0.856 9
 UniProt:P62994 Grb2  3 0.822 5
 UniProt:P04626 ERBB2  20 0.821 16
 UniProt:P27986 PIK3R1  16 0.816 6
 UniProt:P22681 CBL  20 0.77 5
 UniProt:P21860 ERBB3      0.762 7
 UniProt:O95782 AP2A1  5 0.725 6
 UniProt:Q96CW1 AP2M1  6 0.643 5
 UniProt:O94973 AP2A2  6 0.643 4
 UniProt:Q16832 DDR2  1 0.632 3
 UniProt:Q15303 ERBB4      0.609 6
 UniProt:Q12774 ARHGEF5  1 0.597 4
 UniProt:P05067 APP  20 0.589 6
 UniProt:P06213 INSR  6 0.573 2
 UniProt:Q9UM73 ALK  20 0.569 3
 UniProt:P29353 SHC1  5 0.564 2
 UniProt:Q07889 SOS1  3 0.564 2
 UniProt:P35968 KDR  5 0.564 2
 UniProt:Q13137 CACO2      0.553 3
 UniProt:P26954  4 0.544 4
 UniProt:Q9UQC2 GAB2  5 0.544 2
 UniProt:P33151 CDH5  2 0.544 2
 UniProt:P16573  11 0.544 3
 UniProt:P63010 AP2B1  4 0.527 3
 UniProt:Q05655 PRKCD  12 0.527 3
 UniProt:P63104 YWHAZ  2 0.527 2
 UniProt:Q93008 USP9X  1 0.527 3
 UniProt:Q38SD2 LRRK1      0.527 3
 UniProt:Q8TF42 UBS3B      0.527 3
 UniProt:P32927 CSF2RB  6 0.527 4
 UniProt:Q9H706 GARE1      0.527 4
 UniProt:P13569 CFTR  17 0.519 6
 UniProt:P03495 NS1      0.508 2
 UniProt:P46108 CRK  1 0.483 3
 UniProt:Q02763 TEK  2 0.462 2
 UniProt:Q08345-1 DDR1      0.462 4
 UniProt:A9UF07 A9UF07      0.462 4
 UniProt:P04629 NTRK1  4 0.462 2
Cite Us!