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AP2A2(1-939) [secretory granule membrane]
Stable Identifier
R-HSA-6800412
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule membrane
Synonyms
Adaptor protein AP2A2
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
AP2A2(1-939) [secretory granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O94973 AP2A2
Gene Names
AP2A2, ADTAB, CLAPA2, HIP9, HYPJ, KIAA0899
Chain
chain:1-939
Reference Genes
BioGPS Gene:161 AP2A2
COSMIC (genes):AP2A2 AP2A2
CTD Gene:161 AP2A2
dbSNP Gene:161 AP2A2
ENSEMBL:ENSG00000183020 AP2A2
HGNC:562 AP2A2
KEGG Gene (Homo sapiens):161 AP2A2
Monarch:161 AP2A2
NCBI Gene:161 AP2A2
OMIM:607242 AP2A2
UCSC:O94973 AP2A2
Reference Transcript
RefSeq:NM_012305.3 AP2A2
RefSeq:NM_001242837.1 AP2A2
Other Identifiers
0005340021
11741016_a_at
11741017_s_at
11755014_a_at
161
16720440
211779_x_at
212159_x_at
212161_3p_at
212161_at
215764_3p_x_at
215764_x_at
32228_at
3316451
3316452
3316453
3316454
3316455
3316471
3316477
3316481
3316484
3316488
3316492
3316493
3316494
3316502
3316508
3316512
3316514
3316515
3316516
3316520
3316528
3316532
3316540
3316542
3316543
3316544
3316546
3316547
3316548
3316549
3316550
3316551
3316552
3316553
3316554
3316555
3316556
3316557
3316558
3316559
3316560
3316562
7937533
A_14_P126629
A_23_P21853
A_24_P339974
A_24_P932418
A_33_P3311863
GE53571
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005764
GO:0005768
GO:0005773
GO:0005829
GO:0005886
GO:0005905
GO:0006810
GO:0006886
GO:0006897
GO:0006898
GO:0007165
GO:0007267
GO:0008150
GO:0008289
GO:0009056
GO:0015031
GO:0016020
GO:0016192
GO:0019886
GO:0019899
GO:0019900
GO:0019901
GO:0019904
GO:0030117
GO:0030122
GO:0030131
GO:0030666
GO:0030667
GO:0030669
GO:0030674
GO:0031410
GO:0032802
GO:0032991
GO:0034383
GO:0035615
GO:0036020
GO:0043226
GO:0043312
GO:0044403
GO:0045334
GO:0048013
GO:0048856
GO:0050690
GO:0060071
GO:0061024
GO:0072583
GO:0097718
GO:0101003
GO:0140312
HMNXSV003023222
HMNXSV003045833
Hs.19121.0.S2_3p_a_at
Hs.19121.0.S2_3p_at
Hs.19121.0.S2_3p_x_at
Hs.19121.1.S1_3p_a_at
Hs.19121.1.S1_3p_at
ILMN_1803779
PH_hs_0001684
TC11000036.hg
g13544040_3p_s_at
Participates
as a member of
Secretory granule membrane proteins [secretory granule membrane] (Homo sapiens)
Other forms of this molecule
AP2A2(1-939) [endolysosome membrane]
AP2A2(1-939) [ficolin-1-rich granule membrane]
AP2A2(1-939) [plasma membrane]
AP2A2(1-939) [clathrin-coated endocytic vesicle membrane]
AP2A2(1-939) [cytosol]
Inferred To
AP-2alpha [secretory granule membrane]
(Drosophila melanogaster)
apa-2 [secretory granule membrane]
(Caenorhabditis elegans)
apl3 [secretory granule membrane]
(Schizosaccharomyces pombe)
ap2a1-2 [secretory granule membrane]
(Dictyostelium discoideum)
AP2A2(1-939) [secretory granule membrane]
(Plasmodium falciparum)
AP2A2 [secretory granule membrane]
(Canis familiaris)
AP2A2 [secretory granule membrane]
(Gallus gallus)
AP2A2 [secretory granule membrane]
(Sus scrofa)
Ap2a2 [secretory granule membrane]
(Mus musculus)
Ap2a2 [secretory granule membrane]
(Rattus norvegicus)
APL3 [secretory granule membrane]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_036437.1
,
NP_001229766.1
OpenTargets
ENSG00000183020
GeneCards
O94973
HPA
ENSG00000183020-AP2A2
Ensembl
ENSP00000327694
,
ENST00000332231
,
ENSP00000413234
,
ENST00000528815
,
ENST00000448903
,
ENSP00000431630
,
ENSG00000183020
PRO
O94973
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29353 SHC1
5
p-Y427-SHC1 [cytosol]
(R-HSA-74684)
SHC1 [cytosol]
(R-HSA-74680)
p-Y349,Y350-SHC1 [cytosol]
(R-HSA-180276)
p-Y-SHC1 [cytosol]
(R-HSA-162568)
p-Y349,Y350,Y427-SHC1 [cytosol]
(R-HSA-912321)
0.643
4
UniProt:Q96CW1 AP2M1
6
AP2M1 [clathrin-coated endocytic vesicle membrane]
(R-HSA-2130423)
AP2M1 [cytosol]
(R-HSA-182227)
AP2M1 [plasma membrane]
(R-HSA-167585)
AP2M1 [endolysosome membrane]
(R-HSA-6784828)
AP2M1 [lysosomal membrane]
(R-HSA-196144)
p-T156 AP2M1 [cytosol]
(R-HSA-8856805)
0.527
2
UniProt:P98078
3
Dab2 [lysosomal membrane]
(R-MMU-2980807)
Dab2 [cytosol]
(R-MMU-8862456)
Dab2 [plasma membrane]
(R-MMU-2980808)
0.499
2
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