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RFFL [nucleoplasm]
Stable Identifier
R-HSA-6804433
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
E3 ubiquitin-protein ligase rififylin, CARP2, Caspases-8 and -10-associated RING finger protein 2, FYVE-RING finger protein Sakura, Fring, RNF34L, RING finger protein 34-like, RNF189, RING finger protein 189
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Expression and Degradation (Homo sapiens)
Regulation of TP53 Degradation (Homo sapiens)
RNF34 or RFFL ubiquitinates phosphorylated TP53 (Homo sapiens)
RNF34,RFFL [nucleoplasm] (Homo sapiens)
RFFL [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WZ73 RFFL
Gene Names
RFFL, RNF189, RNF34L
Chain
chain:1-363
Reference Genes
COSMIC (genes):RFFL RFFL
dbSNP Gene:117584 RFFL
ENSEMBL:ENSG00000092871 RFFL
Participates
as a member of
RNF34,RFFL [nucleoplasm] (Homo sapiens)
Inferred To
Rffl [nucleoplasm]
(Mus musculus)
Rffl [nucleoplasm]
(Rattus norvegicus)
RFFL [nucleoplasm]
(Bos taurus)
RFFL [nucleoplasm]
(Sus scrofa)
rffl [nucleoplasm]
(Danio rerio)
rffl [nucleoplasm]
(Xenopus tropicalis)
dRNF34 [nucleoplasm]
(Drosophila melanogaster)
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29353 SHC1
5
p-Y-SHC1 [cytosol]
(R-HSA-162568)
SHC1 [cytosol]
(R-HSA-74680)
p-Y349,Y350,Y427-SHC1 [cytosol]
(R-HSA-912321)
p-Y349,Y350-SHC1 [cytosol]
(R-HSA-180276)
p-Y427-SHC1 [cytosol]
(R-HSA-74684)
0.527
3
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