p-5Y-NTRK1 [plasma membrane]

Stable Identifier
R-HSA-3009413
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
p-NTRK1, High affinity nerve growth factor receptor, NTRK1_HUMAN, NTRK1
Icon
p-5Y-NTRK1 [plasma membrane] icon
p-5Y-NTRK1 [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P04629 NTRK1
Gene Names
NTRK1, MTC, TRK, TRKA
Chain
signal peptide:1-32, chain:33-796
Reference Genes
BioGPS Gene:4914 NTRK1
COSMIC (genes):NTRK1 NTRK1
CTD Gene:4914 NTRK1
dbSNP Gene:4914 NTRK1
ENSEMBL:ENSG00000198400 NTRK1
ENSEMBL_homo_sapiens_GENE:ENSG00000198400 NTRK1
HGNC:8031 NTRK1
KEGG Gene (Homo sapiens):4914 NTRK1
Monarch:4914 NTRK1
NCBI Gene:4914 NTRK1
OMIM:191315 NTRK1
UCSC:P04629 NTRK1
Reference Transcript
Other Identifiers
0000130093
11741674_a_at
16672186
1892_s_at
1HE7
1SHC
1WWA
1WWW
208605_s_at
2361762
2361765
2361767
2361768
2361769
2361770
2361771
2361773
2361774
2361775
2361776
2361777
2361778
2361779
2361781
2361783
2361784
2361785
2361787
2361789
2361790
2IFG
2N90
35799
36805_s_at
4606
4914
4AOJ
4CRP
4F0I
4GT5
4PMM
4PMP
4PMS
4PMT
4YNE
4YPS
5H3Q
5I8A
5JFS
5JFV
5JFW
5JFX
5KMI
5KMJ
5KMK
5KML
5KMM
5KMN
5KMO
5KVT
5WR7
6D1Y
6D1Z
6D20
76570
7906244
A_23_P34804
A_24_P265506
AAA36770
AAH62580
AAI36555
AAI44240
AAP88292
AHW56542
BAA34355
BAG35582
CAA27243
CAA29888
CAA44719
CAA59936
CAB004606
CCDS1161
CCDS30890
CCDS30891
E9PQG0
ENSG00000198400
ENSP00000357179
ENSP00000376120
ENSP00000431418
ENST00000368196
ENST00000392302
ENST00000524377
EntrezGene:4914
g4585711_3p_a_at
GE57874
GO:0000003
GO:0000166
GO:0000186
GO:0000902
GO:0001934
GO:0002376
GO:0003674
GO:0004672
GO:0004713
GO:0004714
GO:0004888
GO:0005004
GO:0005030
GO:0005166
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005886
GO:0005887
GO:0006464
GO:0006468
GO:0006950
GO:0007165
GO:0007169
GO:0007267
GO:0007275
GO:0007399
GO:0007411
GO:0007568
GO:0007611
GO:0007623
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0009058
GO:0009314
GO:0009968
GO:0009986
GO:0010465
GO:0010623
GO:0010976
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0019233
GO:0019899
GO:0019900
GO:0021553
GO:0022607
GO:0030154
GO:0030183
GO:0030424
GO:0030425
GO:0031410
GO:0031667
GO:0031901
GO:0031902
GO:0032991
GO:0034641
GO:0035094
GO:0038083
GO:0038179
GO:0038180
GO:0040011
GO:0042490
GO:0042493
GO:0042803
GO:0043025
GO:0043066
GO:0043068
GO:0043121
GO:0043167
GO:0043226
GO:0043235
GO:0043410
GO:0043524
GO:0043547
GO:0046579
GO:0046777
GO:0048011
GO:0048013
GO:0048015
GO:0048406
GO:0048485
GO:0048678
GO:0048856
GO:0050877
GO:0050965
GO:0050966
GO:0051092
GO:0051599
GO:0051602
GO:0051965
GO:0051968
GO:0060009
GO:0060384
GO:0060385
GO:0061368
GO:0070374
GO:0071316
GO:0071363
GO:1901215
GO:1990090
HGNC:8031
HPA035799
HPA076570
ILMN_1731777
ILMN_1770307
ILMN_2326075
IPR000483
IPR000719
IPR001245
IPR001611
IPR002011
IPR007110
IPR008266
IPR011009
IPR013783
IPR017441
IPR020461
IPR020635
IPR020777
IPR031635
IPR032675
IPR036179
J3KP20
LRG_261
MIM:155240
MIM:191315
MIM:256800
NM_001007792
NM_001012331
NM_002529
NP_001007793
NP_001012331
NP_002520
NTRK1
NTRK1-202
NTRK1-203
NTRK1-206
PF07714
PF13855
PF16920
PH_hs_0019265
PR00109
PR01939
PR01940
SM00082
SM00219
TC01001328.hg
uc001fqf.2
uc001fqh.2
uc001fqi.2
UPI000013D5D3
UPI0000204AA8
UPI00003665B8
X5DR71
Participant Of
hasComponent
Other forms of this molecule
p-5Y-NTRK1 [Golgi membrane]
NTRK1 [Golgi membrane]
NTRK1 [plasma membrane]
Inferred To
Ghost homologue of p-5Y-NTRK1 [plasma membrane] (Taeniopygia guttata)
Homologues of p-5Y-NTRK1 [plasma membrane] (Danio rerio)
Homologues of p-5Y-NTRK1 [plasma membrane] (Gallus gallus)
phospho-p-5Y-NTRK1 [plasma membrane] (Bos taurus)
phospho-p-5Y-NTRK1 [plasma membrane] (Canis familiaris)
phospho-p-5Y-NTRK1 [plasma membrane] (Danio rerio)
phospho-p-5Y-NTRK1 [plasma membrane] (Gallus gallus)
phospho-p-5Y-NTRK1 [plasma membrane] (Mus musculus)
phospho-p-5Y-NTRK1 [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-NTRK1 [plasma membrane] (Sus scrofa)
phospho-p-5Y-NTRK1 [plasma membrane] (Xenopus tropicalis)
Modified Residues
Name
O4'-phospho-L-tyrosine at 490
Coordinate
490
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 670
Coordinate
670
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 674
Coordinate
674
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 675
Coordinate
675
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 785
Coordinate
785
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
GeneCards
ZINC - Substances
ZINC target
PRO
BRENDA (Homo sapiens)
ZINC - Predictions - Purchasable
Orphanet
PDB
Interactors (10)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P01138 NGF  7 0.683 3
 UniProt:P01138-PRO_0000019600 NGF      0.544 2
 UniProt:Q8K4V6 Q8K4V6      0.524 2
 UniProt:O75385 ULK1  7 0.499 2
 UniProt:Q13501 SQSTM1  2 0.499 2
 UniProt:P04629 NTRK1  4 0.488 2
 UniProt:Q99523 SORT1  2 0.463 3
 UniProt:P27986 PIK3R1  15 0.462 2
 UniProt:P19174 PLCG1  6 0.462 2
 UniProt:P29353 SHC1  5 0.462 2