Reactome | PTGES3 [nucleoplasm]

PTGES3 [nucleoplasm]

Stable Identifier

R-HSA-5082403

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Prostaglandin E synthase 3, cPGES

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External Reference Information

External Reference

UniProt:Q15185 PTGES3

Gene Names

PTGES3, P23, TEBP

Chain

chain:1-160

Reference Genes

BioGPS Gene:10728 PTGES3

COSMIC (genes):PTGES3 PTGES3

CTD Gene:10728 PTGES3

dbSNP Gene:10728 PTGES3

ENSEMBL:ENSG00000110958 PTGES3

HGNC:16049 PTGES3

KEGG Gene (Homo sapiens):10728 PTGES3

Monarch:10728 PTGES3

NCBI Gene:10728 PTGES3

OMIM:607061 PTGES3

UCSC:Q15185 PTGES3

Reference Transcript

Other Identifiers

0000450193

10728

11743372_s_at

11747662_x_at

11751818_x_at

11753366_x_at

16766283

1EJF

1LG0

200627_at

2421920

2421921

2473546

2793347

3163060

32548_at

3261927

34319

3458058

3458059

3458060

3458061

3458065

3458070

3458073

3458076

3458078

3458092

38672

38673

7964250

A0A024RB32

A0A087WYT3

AAA18537

AAH03005

AAH21167

AC117378

AK291945

AK295208

AK298147

AK298160

B4DDC6

BAF84634

BAG58204

BAG60423

BAG60433

BC003005

BC021167

CAB034319

CCDS31836

CCDS61158

CCDS61159

CCDS61160

CH471054

EAW96953

EAW96956

EAW96957

EAW96958

ENSG00000110958

ENSP00000262033

ENSP00000402385

ENSP00000405299

ENSP00000414892

ENST00000262033

ENST00000262033.10

ENST00000414274

ENST00000414274.7

ENST00000436399

ENST00000436399.6

ENST00000448157

ENST00000448157.6

EntrezGene:10728

EntrezGene:PTGES3

g12804292_3p_at

g12804292_3p_x_at

GE79257

GO:0000723

GO:0000781

GO:0001516

GO:0003674

GO:0003720

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005694

GO:0005697

GO:0005737

GO:0005829

GO:0006259

GO:0006457

GO:0006629

GO:0006631

GO:0006633

GO:0006693

GO:0006805

GO:0006950

GO:0007004

GO:0007165

GO:0008150

GO:0009058

GO:0016779

GO:0016853

GO:0019371

GO:0019899

GO:0022607

GO:0022618

GO:0032991

GO:0034641

GO:0042327

GO:0042592

GO:0043226

GO:0044281

GO:0050220

GO:0050821

GO:0051082

GO:0051085

GO:0051087

GO:0051131

GO:0051276

GO:0051879

GO:0051973

GO:0065003

GO:0070182

GO:0101031

GO:1900034

GO:1905323

HGNC:16049

HPA038672

HPA038673

ILMN_1667916

ILMN_1719749

ILMN_1752566

IPR007052

IPR008978

L24804

L24804_at

MIM:607061

NM_001282601

NM_001282602

NM_001282603

NM_001282605

NM_006601

NP_001269530

NP_001269531

NP_001269532

NP_001269534

NP_006592

PF04969

PTGES3

PTGES3-201

PTGES3-202

PTGES3-203

PTGES3-204

TC12001612.hg

TC12002910.hg

UPI0000052BAD

UPI0000052BAE

UPI00006DFC9F

UPI00017A7309

XM_005268576

XM_006719199

XM_011537773

XM_011537774

XP_005268633

XP_006719262

XP_011536075

XP_011536076

Participant Of

output

hasComponent

Other forms of this molecule

PTGES3 [cytosol]

Inferred To

Ghost homologue of PTGES3 [nucleoplasm] (Gallus gallus)

wos2 [nucleoplasm] (Schizosaccharomyces pombe)

PTGES3 [nucleoplasm] (Bos taurus)

PTGES3 [nucleoplasm] (Dictyostelium discoideum)

PTGES3 [nucleoplasm] (Drosophila melanogaster)

PTGES3 [nucleoplasm] (Plasmodium falciparum)

PTGES3 [nucleoplasm] (Sus scrofa)

PTGES3 [nucleoplasm] (Xenopus tropicalis)

Ptges3 [nucleoplasm] (Mus musculus)

Ptges3 [nucleoplasm] (Rattus norvegicus)

SBA1 [nucleoplasm] (Saccharomyces cerevisiae)

ATP5F1B [nucleoplasm] (Canis familiaris)

daf-41 [nucleoplasm] (Caenorhabditis elegans)

ptges3b [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_001269534.1, NP_001269531.1, NP_006592.3, NP_001269533.1, NP_001269530.1, NP_001269532.1

OpenTargets

ENSG00000110958

GeneCards

Q15185

HPA

ENSG00000110958-PTGES3

Ensembl

ENSP00000262033, ENST00000436399, ENSP00000402385, ENST00000414274, ENSG00000110958, ENSP00000414892, ENSP00000405299, ENST00000448157, ENST00000262033

PRO

Q15185

HMDB Protein

HMDBP10674

PDB

1EJF, 1LG0

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P07900 HSP90AA1	8	HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [cytosol] (R-HSA-192864) HSP90AA1 [lysosomal lumen] (R-HSA-9622850)	0.756	6
UniProt:P08238 HSP90AB1	6	HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [lysosomal lumen] (R-HSA-9622846)	0.744	4
UniProt:P53041 PPP5C	2	PPP5C [cytosol] (R-HSA-5675402) PPP5C [nucleoplasm] (R-HSA-5683410)	0.527	2
UniProt:O14654 IRS4	2	IRS4 [plasma membrane] (R-HSA-2424297) p-Y-IRS4 [plasma membrane] (R-HSA-2424302)	0.499	2
UniProt:Q9UKV8 AGO2	2	AGO2 [cytosol] (R-HSA-209723) EIF2C2 [nucleoplasm] (R-HSA-5578701)	0.499	3
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2