Reactome | IFT122 [ciliary tip]

IFT122 [ciliary tip]

Stable Identifier

R-HSA-5625346

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

ciliary tip

Synonyms

IFT-A 122, SPG, WDR10, WDR140, IFT A

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9HBG6 IFT122

Gene Names

IFT122, SPG, WDR10, WDR140

Chain

chain:1-1241

Reference Genes

BioGPS Gene:55764 IFT122

COSMIC (genes):IFT122 IFT122

CTD Gene:55764 IFT122

dbSNP Gene:55764 IFT122

ENSEMBL:ENSG00000163913 IFT122

HGNC:13556 IFT122

KEGG:hsa:55764 IFT122

Monarch:55764 IFT122

NCBI Gene:55764 IFT122

OMIM:606045 IFT122

UCSC:Q9HBG6 IFT122

Reference Transcript

Other Identifiers

16945375

241336_PM_at

241336_at

2641636

2641642

2641644

2641668

2641669

2641670

2641671

2641672

2641676

2641677

2641678

2641679

2641680

2641681

2641682

2641683

2641684

2641685

2641687

2641691

2641692

2641693

2641694

2641697

2641698

2641701

2641702

2641706

2641707

2641711

2641712

2641714

2641715

2641719

2641720

2641722

2641724

2641725

2641726

2641734

2641735

2641736

2641737

2641738

2641740

2641741

2641747

2641748

2641749

2641750

2641753

2641754

2641755

2641759

2641761

2694505

2694509

55764

63162_f_at

63163_f_at

8082523

A_14_P112088

A_14_P135646

A_19_P00317132

GE55904

GE85217

GE857129

GO:0001843

GO:0005515

GO:0005654

GO:0005737

GO:0005815

GO:0005829

GO:0005856

GO:0005929

GO:0007018

GO:0007399

GO:0007507

GO:0008589

GO:0010172

GO:0016020

GO:0021513

GO:0030030

GO:0030991

GO:0031514

GO:0031965

GO:0032391

GO:0035050

GO:0035115

GO:0035556

GO:0035720

GO:0035721

GO:0036064

GO:0042073

GO:0042995

GO:0043226

GO:0044782

GO:0045184

GO:0045879

GO:0048593

GO:0048856

GO:0060173

GO:0060271

GO:0060971

GO:0061512

GO:0072594

GO:0097542

GO:0097730

GO:1905515

HMNXSV003015698

HMNXSV003025438

Hs.193981.0.A1_3p_at

ILMN_1666593

ILMN_1720724

ILMN_1742379

ILMN_2366177

PH_hs_0022326

TC03000692.hg

p11496

Participates

as a component of

IFT A [ciliary tip] (Homo sapiens)

Other forms of this molecule

IFT122 [cilium]

Inferred To

daf-10 [ciliary tip] (Caenorhabditis elegans)

Ift122 [ciliary tip] (Mus musculus)

Ift122 [ciliary tip] (Rattus norvegicus)

ift122 [ciliary tip] (Xenopus tropicalis)

IFT122 [ciliary tip] (Bos taurus)

IFT122 [ciliary tip] (Canis familiaris)

IFT122 [ciliary tip] (Gallus gallus)

IFT122 [ciliary tip] (Sus scrofa)

Cross References

RefSeq

NP_443711.2, NP_060732.2, NP_001267474.1, NP_443716.1, NP_443715.1, NP_001267470.1, NP_001267475.1

OpenTargets

ENSG00000163913

ENSEMBL

ENSG00000163913, ENST00000507564, ENST00000689005, ENSP00000323973, ENST00000296266, ENSP00000509186, ENSP00000324005, ENSP00000324165, ENSP00000510168, ENSP00000296266, ENST00000693233, ENST00000349441, ENSP00000425536, ENST00000348417, ENST00000347300

HPA

ENSG00000163913-IFT122

GeneCards

IFT122

PRO

Q9HBG6

Pharos - Targets

Q9HBG6

Orphanet

IFT122

PDB

8BBG, 8BBE, 8FH3, 8BBF, 8FGW

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.865	8
UniProt:Q96RY7 IFT140	2	IFT140 [cilium] (R-HSA-5610382) IFT140 [ciliary tip] (R-HSA-5625345)	0.823	7
UniProt:Q8NEZ3 WDR19	2	WDR19 [cilium] (R-HSA-5610446) WDR19 [ciliary tip] (R-HSA-5625347)	0.8	7
UniProt:Q96FT9 IFT43	2	IFT43 [cilium] (R-HSA-5617619) IFT43 [ciliary tip] (R-HSA-5625348)	0.8	7
UniProt:Q9P2L0 WDR35	2	WDR35 [ciliary tip] (R-HSA-5625351) WDR35 [cilium] (R-HSA-5610448)	0.74	5
UniProt:Q7Z4L5 TTC21B	2	TTC21B [ciliary tip] (R-HSA-5625349) TTC21B [cilium] (R-HSA-5610430)	0.704	5
UniProt:Q86VG3 IFTAP			0.643	4
UniProt:O00295 TULP2			0.643	4
UniProt:Q99615 DNAJC7	2	DNAJC7 [nucleoplasm] (R-HSA-5255408) DNAJC7 [cytosol] (R-HSA-5252099)	0.643	3
UniProt:Q9Q2G4 Q9Q2G4			0.558	3
UniProt:Q15185 PTGES3	2	PTGES3 [nucleoplasm] (R-HSA-5082403) PTGES3 [cytosol] (R-HSA-265269)	0.527	3
UniProt:Q9Y2S2 CRYL1	1	CRYL1 [cytosol] (R-HSA-5661279)	0.527	2
UniProt:O60884 DNAJA2	1	DNAJA2 [cytosol] (R-HSA-3371555)	0.527	3
UniProt:Q96FT9-2 IFT43			0.527	3
UniProt:Q9P2L0-2 WDR35			0.527	2
UniProt:O00311 CDC7	1	CDC7 [nucleoplasm] (R-HSA-51781)	0.508	2
UniProt:Q9BU61 NDUFAF3	1	NDUFAF3 [mitochondrial inner membrane] (R-HSA-5689126)	0.508	2
UniProt:Q4G0X9 CCD40			0.508	2
UniProt:Q01813 PFKP	1	PFKP [cytosol] (R-HSA-71452)	0.508	2