Reactome | AIP [nucleoplasm]

AIP [nucleoplasm]

Stable Identifier

R-HSA-8937156

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

AH receptor-interacting protein, AIP_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00170 AIP

Gene Names

AIP, XAP2

Chain

chain:1-330

Reference Genes

BioGPS Gene:9049 AIP

COSMIC (genes):AIP AIP

CTD Gene:9049 AIP

dbSNP Gene:9049 AIP

ENSEMBL:ENSG00000110711 AIP

HGNC:358 AIP

KEGG Gene (Homo sapiens):9049 AIP

Monarch:9049 AIP

NCBI Gene:9049 AIP

OMIM:605555 AIP

UCSC:O00170 AIP

Reference Transcript

Other Identifiers

0006110022

11715980_at

16727908

201781_s_at

201782_s_at

3337140

3337141

3337142

3337145

3337147

3337149

3337150

3337152

3337153

36586_at

7941927

9049

GO:0000413

GO:0003674

GO:0003712

GO:0003713

GO:0003755

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006457

GO:0006464

GO:0006605

GO:0006626

GO:0006805

GO:0006810

GO:0007005

GO:0007165

GO:0008134

GO:0008150

GO:0009058

GO:0010738

GO:0015031

GO:0016020

GO:0016853

GO:0017162

GO:0022417

GO:0032991

GO:0034641

GO:0034751

GO:0035722

GO:0036004

GO:0043226

GO:0045893

GO:0051082

GO:0051344

GO:0051604

HMNXSV003056212

Hs.75305.0.S1_3p_a_at

ILMN_2103841

PH_hs_0024902

PH_hs_0035930

TC11000693.hg

U78521_at

Participates

as a component of

Other forms of this molecule

AIP [cytosol]

Inferred To

Aip [nucleoplasm] (Mus musculus)

Aip [nucleoplasm] (Rattus norvegicus)

aipr-1 [nucleoplasm] (Caenorhabditis elegans)

AIP [nucleoplasm] (Canis familiaris)

AIP [nucleoplasm] (Gallus gallus)

AIP [nucleoplasm] (Sus scrofa)

AIP [nucleoplasm] (Xenopus tropicalis)

Ghost homologue of AIP [nucleoplasm] (Drosophila melanogaster)

aip [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_003968.3, NP_001289888.1, NP_001289889.1

OpenTargets

ENSG00000110711

GeneCards

O00170

HPA

ENSG00000110711-AIP

Ensembl

ENSG00000110711, ENST00000279146, ENSP00000279146

PRO

O00170

Pharos - Targets

O00170

Orphanet

18425

GlyGen

O00170

PDB

4APO, 4AIF, 2LKN

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08238 HSP90AB1	6	HSP90AB1 [lysosomal lumen] (R-HSA-9622846) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491)	0.829	8
UniProt:O00408 PDE2A	1	PDE2A [cytosol] (R-HSA-418499)	0.602	6
UniProt:P00533 EGFR	20	p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211)	0.553	2
UniProt:Q92985 IRF7	5	p-S477,S479-IRF7 [cytosol] (R-HSA-450318) IRF7 [endosome membrane] (R-HSA-450274) IRF7 [cytosol] (R-HSA-450281) p-S477,S479-IRF7 [nucleoplasm] (R-HSA-450270) K63polyUb-IRF7 [endosome membrane] (R-HSA-975154)	0.499	2
UniProt:P35869 AHR	2	AHR [nucleoplasm] (R-HSA-8937190) AHR [cytosol] (R-HSA-8936842)	0.463	3

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