Reactome | TBRG4 [mitochondrial matrix]

TBRG4 [mitochondrial matrix]

Stable Identifier

R-HSA-9837166

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

fullName evidence="9"FAST kinase domain-containing protein 4, FAKD4_HUMAN, FASTKD4

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q969Z0 TBRG4

Gene Names

TBRG4, CPR2, FASTKD4, KIAA0948

Chain

transit peptide:1-107, chain:108-631

Reference Genes

BioGPS Gene:9238 TBRG4

COSMIC (genes):TBRG4 TBRG4

CTD Gene:9238 TBRG4

dbSNP Gene:9238 TBRG4

ENSEMBL:ENSG00000136270 TBRG4

ENSEMBL_homo_sapiens_GENE:ENSG00000136270.14 TBRG4

HGNC:17443 TBRG4

KEGG Gene (Homo sapiens):9238 TBRG4

Monarch:9238 TBRG4

NCBI Gene:9238 TBRG4

OMIM:611325 TBRG4

UCSC:Q969Z0 TBRG4

Reference Transcript

Other Identifiers

11734700_a_at

17057433

220789_PM_s_at

220789_s_at

3049027

3049028

3049029

3049031

3049032

3049033

3049035

3049036

3049039

3049042

3049044

3049045

3049050

3049052

3049053

3049057

3049058

3049059

3049060

3049063

51855_at

8139468

9238

A_23_P215658

GE54111

GO:0000963

GO:0003723

GO:0005515

GO:0005739

GO:0005759

GO:0008284

GO:0016071

GO:0035770

GO:0043226

GO:0044528

GO:0051726

GO:0090615

GO:0140053

ILMN_1783728

ILMN_1809047

ILMN_2414848

PH_hs_0028003

TC07001351.hg

g4758045_3p_s_at

Participates

as a component of

TBRG4:12S rRNA,16S rRNA, MT-ATP6 mRNA, MTCO1,2,3 mRNA,MT-CYB mRNA,MT-ND1,2,3,4,5,6 mRNA [mitochondrial matrix] (Homo sapiens)

as an input of

TBRG4 (FASTKD4) binds mitochondrial rRNAs and mRNAs (Homo sapiens)

Inferred To

Dmel\CG13850 [mitochondrial matrix] (Drosophila melanogaster)

TBRG4 [mitochondrial matrix] (Bos taurus)

TBRG4 [mitochondrial matrix] (Canis familiaris)

TBRG4 [mitochondrial matrix] (Gallus gallus)

TBRG4 [mitochondrial matrix] (Plasmodium falciparum)

TBRG4 [mitochondrial matrix] (Sus scrofa)

Homologues of TBRG4 [mitochondrial matrix] (Plasmodium falciparum)

Tbrg4 [mitochondrial matrix] (Mus musculus)

Tbrg4 [mitochondrial matrix] (Rattus norvegicus)

tbrg4 [mitochondrial matrix] (Danio rerio)

tbrg4 [mitochondrial matrix] (Xenopus tropicalis)

fask-1 [mitochondrial matrix] (Caenorhabditis elegans)

Cross References

RefSeq

NP_004740.2, NP_954573.1, NP_112162.1

OpenTargets

ENSG00000136270

GeneCards

Q969Z0

HPA

ENSG00000136270-TBRG4

Ensembl

ENSP00000420597, ENST00000494076, ENSG00000136270, ENST00000258770, ENSP00000354992, ENSP00000258770, ENST00000361278, ENST00000395655, ENSP00000379016

PRO

Q969Z0

Pharos - Targets

Q969Z0

Interactors (37)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P52815 MRPL12	2	MRPL12 [mitochondrial matrix] (R-HSA-9839674) MRPL12 [mitochondrial inner membrane] (R-HSA-5368256)	0.615	3
UniProt:Q9NRY5 FAM114A2	2	FAM114A2(1-327)-BRAF(439-766) fusion [cytosol] (R-HSA-6802321) FAM114A2(1-327)-p-BRAF(439-766) fusion [cytosol] (R-HSA-6802525)	0.601	4
UniProt:Q6RW13 AGTRAP	2	AGTRAP(1-159)-p-BRAF(288-545) fusion [cytosol] (R-HSA-6802511) AGTRAP(1-159)-BRAF(288-545) fusion [cytosol] (R-HSA-6802262)	0.556	3
UniProt:Q8WZ55 BSND	1	BSND [plasma membrane] (R-HSA-2854996)	0.556	3
UniProt:Q8WW34-2 TMEM239			0.556	3
UniProt:Q86X02 CDR2L			0.556	3
UniProt:B7ZLI8 B7ZLI8			0.556	3
UniProt:O15126 SCAMP1	2	SCAMP1 [plasma membrane] (R-HSA-6806161) SCAMP1 [specific granule membrane] (R-HSA-6806140)	0.556	3
UniProt:Q13137 CACO2			0.556	3
UniProt:Q6RW13-2 AGTRAP			0.556	3
UniProt:Q8WV19 SFT2A			0.556	3
UniProt:Q96DZ9-2 CMTM5			0.556	3
UniProt:Q7Z3Y8 KRT27	1	KRT27 [cytosol] (R-HSA-6809587)	0.556	3
UniProt:Q9H400 LIME1			0.556	3
UniProt:Q04118 PRB3			0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:Q9UBN6 TNFRSF10D	1	TNFRSF10D [plasma membrane] (R-HSA-5633374)	0.556	3
UniProt:Q969L2 MAL2			0.556	3
UniProt:Q8IZR5-2 Q8IZR52			0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q8TD16-2 BICD2			0.556	3
UniProt:Q8IZU0 FAM9B			0.556	3
UniProt:Q96D09 GASP2			0.556	3
UniProt:P41587 VIPR2	1	VIPR2 [plasma membrane] (R-HSA-420227)	0.527	2
UniProt:P32970 CD70	1	CD70 [plasma membrane] (R-HSA-5667139)	0.527	3
UniProt:Q9H813 PACC1			0.527	2
UniProt:Q9UQV4 LAMP3			0.527	3
UniProt:Q9P0K9 FRS1L			0.527	2
UniProt:O95274 LYPD3	2	cleaved GPI-LYPD3 [extracellular region] (R-HSA-8941013) GPI-LYPD3 [plasma membrane] (R-HSA-8940752)	0.527	3
UniProt:A2RU67 F234B			0.527	4
UniProt:Q8TCS8 PNPT1	1	PNPT1 [mitochondrial matrix] (R-HSA-9836559)	0.527	2
UniProt:Q01151 CD83			0.527	2
UniProt:Q96FM1 PGAP3			0.499	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	5
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2

Cite Us!