Reactome | ARFGEF2 [cytosol]

ARFGEF2 [cytosol]

Stable Identifier

R-HSA-391301

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y6D5 ARFGEF2

Gene Names

ARFGEF2, ARFGEP2, BIG2

Chain

chain:1-1785

Reference Genes

BioGPS Gene:10564 ARFGEF2

COSMIC (genes):ARFGEF2 ARFGEF2

CTD Gene:10564 ARFGEF2

dbSNP Gene:10564 ARFGEF2

ENSEMBL:ENSG00000124198 ARFGEF2

ENSEMBL_homo_sapiens_GENE:ENSG00000124198.10 ARFGEF2

HGNC:15853 ARFGEF2

KEGG Gene (Homo sapiens):10564 ARFGEF2

Monarch:10564 ARFGEF2

NCBI Gene:10564 ARFGEF2

OMIM:605371 ARFGEF2

UCSC:Q9Y6D5 ARFGEF2

Reference Transcript

RefSeq:NM_006420.2 ARFGEF2

Other Identifiers

10564

11721062_s_at

11721063_a_at

16914628

215931_PM_s_at

215931_s_at

218098_PM_at

218098_at

222518_PM_at

222518_at

31996_at

34484_at

3888056

3888057

3888058

3888065

3888066

3888068

3888069

3888070

3888071

3888076

3888077

3888078

3888080

3888081

3888082

3888083

3888084

3888086

3888089

3888091

3888092

3888093

3888094

3888095

3888096

3888099

3888100

3888101

3888103

3888105

3888106

3888107

3888110

3888111

3888112

3888113

3888114

3888115

3888116

3888117

3888118

3888120

3888123

3888124

3888125

3888127

3888128

3888129

3888130

3888131

3888132

51179_at

67858_at

8063242

88053_at

A_14_P130933

A_14_P135226

A_23_P5995

A_33_P3271925

GE58402

GO:0000139

GO:0001881

GO:0005085

GO:0005515

GO:0005737

GO:0005768

GO:0005794

GO:0005802

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005879

GO:0005929

GO:0006887

GO:0006893

GO:0007032

GO:0008092

GO:0010256

GO:0015031

GO:0016020

GO:0016192

GO:0017022

GO:0023052

GO:0030425

GO:0031410

GO:0032012

GO:0032279

GO:0032280

GO:0032760

GO:0034237

GO:0035556

GO:0042995

GO:0043197

GO:0043226

GO:0043231

GO:0045202

GO:0048471

GO:0050811

GO:0055037

GO:0098772

GO:0098793

GO:0098794

GO:0098978

GO:0098982

HMNXSV003036560

Hs.118249.0.S2_3p_at

Hs.118249.0.S3_3p_at

Hs.118249.1.S1_3p_a_at

ILMN_1789990

PH_hs_0023706

TC20000382.hg

Participates

as a candidate of

unfolded CCT/TRiC substrate candidates [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_006411.2

OpenTargets

ENSG00000124198

GeneCards

Q9Y6D5

HPA

ENSG00000124198-ARFGEF2

Ensembl

ENSG00000124198, ENST00000371917, ENSP00000360985

PRO

Q9Y6D5

Pharos - Targets

Q9Y6D5

Orphanet

15946

HMDB Protein

HMDBP08318

PDB

3L8N, 3SWV

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC5 M	10	M [plasma membrane] (R-COV-9755780) N-glycan M [virion membrane] (R-COV-9694385) M [virion membrane] (R-COV-9694320) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum membrane] (R-COV-9767620) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684)	0.527	2
UniProt:Q14432 PDE3A	1	PDE3A [cytosol] (R-HSA-418505)	0.499	5
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2

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