Reactome | CYB5R1 [platelet alpha granule membrane]

CYB5R1 [platelet alpha granule membrane]

Stable Identifier

R-HSA-8848891

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet alpha granule membrane

Synonyms

NADH-cytochrome b5 reductase 1, NB5R1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UHQ9 CYB5R1

Gene Names

CYB5R1, NQO3A2, UNQ3049/PRO9865

Chain

chain:1-305

Reference Genes

BioGPS Gene:51706 CYB5R1

COSMIC (genes):CYB5R1 CYB5R1

CTD Gene:51706 CYB5R1

dbSNP Gene:51706 CYB5R1

ENSEMBL:ENSG00000159348 CYB5R1

ENSEMBL_homo_sapiens_GENE:ENSG00000159348.13 CYB5R1

HGNC:13397 CYB5R1

KEGG Gene (Homo sapiens):51706 CYB5R1

Monarch:51706 CYB5R1

NCBI Gene:51706 CYB5R1

OMIM:608341 CYB5R1

UCSC:Q9UHQ9 CYB5R1

Reference Transcript

RefSeq:NM_016243.2 CYB5R1

Other Identifiers

11743184_a_at

11748576_a_at

11748855_a_at

16698136

202263_PM_at

202263_at

2451490

2451492

2451494

2451495

2451497

2451499

2451501

2451503

2451505

2451508

2451510

2451513

35329_at

51706

7923516

A_23_P52101

GE62615

GO:0003824

GO:0004128

GO:0005515

GO:0005576

GO:0005615

GO:0005739

GO:0005783

GO:0005789

GO:0005829

GO:0005886

GO:0006629

GO:0006694

GO:0008202

GO:0015701

GO:0016020

GO:0016126

GO:0016491

GO:0031092

GO:0031410

GO:0043226

GO:0070062

GO:0071949

HMNXSV003034575

ILMN_1729237

PH_hs_0023860

TC01003712.hg

g7706454_3p_at

Participates

as a member of

Platelet alpha granule membrane components that are released on degranulation [platelet alpha granule membrane] (Homo sapiens)

Other forms of this molecule

CYB5R1 [plasma membrane]

CYB5R1 [endoplasmic reticulum membrane]

Inferred To

Homologues of CYB5R1 [platelet alpha granule membrane] (Saccharomyces cerevisiae)

CYB5R1 [platelet alpha granule membrane] (Bos taurus)

CYB5R1 [platelet alpha granule membrane] (Canis familiaris)

CYB5R1 [platelet alpha granule membrane] (Danio rerio)

CYB5R1 [platelet alpha granule membrane] (Dictyostelium discoideum)

CYB5R1 [platelet alpha granule membrane] (Drosophila melanogaster)

CYB5R1 [platelet alpha granule membrane] (Mus musculus)

CYB5R1 [platelet alpha granule membrane] (Rattus norvegicus)

CYB5R1 [platelet alpha granule membrane] (Saccharomyces cerevisiae)

CYB5R1 [platelet alpha granule membrane] (Schizosaccharomyces pombe)

CYB5R1 [platelet alpha granule membrane] (Sus scrofa)

AIM33 [platelet alpha granule membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_057327.2

OpenTargets

ENSG00000159348

GeneCards

Q9UHQ9

HPA

ENSG00000159348-CYB5R1

Ensembl

ENSP00000356218, ENST00000367249, ENSG00000159348

PRO

Q9UHQ9

Pharos - Targets

Q9UHQ9

HMDB Protein

HMDBP07263

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:A8MV81 HIGD1C	1	HIGD1C [mitochondrial inner membrane] (R-HSA-9865734)	0.556	3
UniProt:Q9UHF4 IL20RA	1	IL20RA [plasma membrane] (R-HSA-448713)	0.527	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	4

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