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XPO5 [cytosol]
Stable Identifier
R-HSA-847719
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Exportin-5, XPO5_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Gene Silencing by RNA (Homo sapiens)
MicroRNA (miRNA) biogenesis (Homo sapiens)
Exportin complex translocates pre-miRNA to cytosol (Homo sapiens)
RAN:GDP:Exportin-5 [cytosol] (Homo sapiens)
XPO5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HAV4 XPO5
Gene Names
XPO5, KIAA1291, RANBP21
Chain
initiator methionine:, chain:2-1204
Reference Genes
BioGPS Gene:57510 XPO5
COSMIC (genes):XPO5 XPO5
CTD Gene:57510 XPO5
dbSNP Gene:57510 XPO5
ENSEMBL:ENSG00000124571 XPO5
ENSEMBL_homo_sapiens_GENE:ENSG00000124571.18 XPO5
HGNC:17675 XPO5
KEGG Gene (Homo sapiens):57510 XPO5
Monarch:57510 XPO5
NCBI Gene:57510 XPO5
OMIM:607845 XPO5
UCSC:Q9HAV4 XPO5
Reference Transcript
RefSeq:NM_020750.2 XPO5
Other Identifiers
11729164_a_at
11729165_a_at
17019425
223055_PM_s_at
223055_s_at
223056_PM_s_at
223056_s_at
223057_PM_s_at
223057_s_at
2954679
2954680
2954681
2954682
2954683
2954684
2954685
2954686
2954687
2954688
2954689
2954691
2954693
2954696
2954697
2954698
2954700
2954701
2954704
2954707
2954709
2954710
2954718
2954721
2954722
2954723
2954724
2954725
2954726
2954727
2954730
2954733
2954736
2954737
2954738
2954739
2954740
2954742
2954743
2954744
2954745
2954746
2954747
2954748
2954749
2954750
2954751
55709_at
57510
72060_at
78327_at
8126588
A_23_P256855
A_33_P3228366
A_33_P3228375
GE53870
GO:0000049
GO:0003723
GO:0003729
GO:0005049
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006405
GO:0006611
GO:0006886
GO:0006913
GO:0010586
GO:0015031
GO:0016442
GO:0031047
GO:0031267
GO:0035281
GO:0042565
GO:0043226
GO:0070883
GO:0140104
GO:1905172
HMNXSV003042259
Hs.9805.0.S1_3p_a_at
ILMN_1759495
PH_hs_0023015
TC06001751.hg
TC06003653.hg
g10444426_3p_a_at
g12652756_3p_a_at
Participates
as a component of
RAN:GDP:Exportin-5 [cytosol] (Homo sapiens)
Other forms of this molecule
XPO5 [nucleoplasm]
Inferred To
MSN5 [cytosol]
(Saccharomyces cerevisiae)
LOC100486598 [cytosol]
(Xenopus tropicalis)
Ranbp21 [cytosol]
(Drosophila melanogaster)
XPO5 [cytosol]
(Bos taurus)
XPO5 [cytosol]
(Canis familiaris)
XPO5 [cytosol]
(Gallus gallus)
XPO5 [cytosol]
(Schizosaccharomyces pombe)
XPO5 [cytosol]
(Sus scrofa)
xpo5 [cytosol]
(Dictyostelium discoideum)
xpo5.2 [cytosol]
(Xenopus tropicalis)
Homologues of XPO5 [cytosol]
(Xenopus tropicalis)
Xpo5 [cytosol]
(Mus musculus)
Xpo5 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_065801.1
OpenTargets
ENSG00000124571
GeneCards
Q9HAV4
HPA
ENSG00000124571-XPO5
Ensembl
ENSG00000124571
,
ENSP00000265351
,
ENST00000265351
PRO
Q9HAV4
Pharos - Targets
Q9HAV4
PDB
3A6P
,
5YU6
,
5YU7
HMDB Protein
HMDBP08620
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.564
2
UniProt:P0DTC7 7a
5
7a [endolysosome membrane]
(R-COV-9755945)
7a [endoplasmic reticulum membrane]
(R-COV-9727308)
7a [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694750)
7a [endocytic vesicle membrane]
(R-COV-9694645)
7a [virion membrane]
(R-COV-9694648)
0.547
2
UniProt:Q68D85 NCR3LG1
1
NCR3LG1 [plasma membrane]
(R-HSA-5683240)
0.527
3
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
8
UniProt:P05919 vpu
6
VPU (P05919) protein [cytosol]
(R-HIV-173223)
VPU (P05919) [endoplasmic reticulum membrane]
(R-HIV-180550)
VPU (P05919) protein [extracellular region]
(R-HIV-175522)
VPU (P05919) protein [nucleoplasm]
(R-HIV-175200)
VPU (P05919) [Golgi membrane]
(R-HIV-3149439)
VPU (P05919) [plasma membrane]
(R-HIV-3149423)
0.462
2
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