Reactome | p-CHP1 [plasma membrane]

p-CHP1 [plasma membrane]

Stable Identifier

R-HSA-5333747

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

phosphorylated Calcineurin B homologous protein 1, CHP1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q99653 CHP1

Gene Names

CHP1, CHP

Chain

initiator methionine:, chain:2-195

Reference Genes

BioGPS Gene:11261 CHP1

COSMIC (genes):CHP1 CHP1

CTD Gene:11261 CHP1

dbSNP Gene:11261 CHP1

ENSEMBL:ENSG00000187446 CHP1

HGNC:17433 CHP1

KEGG:hsa:11261 CHP1

Monarch:11261 CHP1

NCBI Gene:11261 CHP1

OMIM:606988 CHP1

UCSC:Q99653 CHP1

Reference Transcript

RefSeq:NM_007236.5 CHP1

Other Identifiers

11261

11754517_a_at

11756650_a_at

207993_PM_s_at

207993_s_at

214665_PM_s_at

214665_s_at

2862214

2934425

35018_at

3590342

3590343

3590347

3590348

3590349

3590352

3590353

3590355

3590356

3590359

3590360

3590361

3590362

3590363

3590364

3590366

3590367

3907071

49347_at

7982878

80180_at

84419_at

A_14_P116755

A_23_P100111

A_23_P112801

GE55456

GE59284

GO:0000139

GO:0001578

GO:0001933

GO:0004860

GO:0005215

GO:0005509

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005793

GO:0005856

GO:0005886

GO:0005925

GO:0006355

GO:0006469

GO:0006611

GO:0006813

GO:0006886

GO:0006913

GO:0007010

GO:0007264

GO:0008017

GO:0008092

GO:0010923

GO:0012505

GO:0015031

GO:0015385

GO:0015459

GO:0015630

GO:0016020

GO:0019900

GO:0022406

GO:0030133

GO:0031122

GO:0031397

GO:0031410

GO:0031953

GO:0032088

GO:0032417

GO:0035725

GO:0042308

GO:0043226

GO:0045121

GO:0046872

GO:0048306

GO:0050821

GO:0051222

GO:0051453

GO:0055085

GO:0060050

GO:0061024

GO:0061025

GO:0070062

GO:0070885

GO:0071073

GO:0071468

GO:0090314

GO:0098772

GO:1990351

HMNXSV003016165

HMNXSV003035406

Hs.85301.3.S1_3p_s_at

ILMN_1779401

PH_hs_0030056

TC15000304.hg

U61538_at

g6005730_3p_a_at

Participates

as a component of

p-CHP1:Ca2+ [plasma membrane] (Homo sapiens)

Inferred To

phospho-chpf-1 [plasma membrane] (Caenorhabditis elegans)

phospho-chp1 [plasma membrane] (Xenopus tropicalis)

phospho-CHP1 [plasma membrane] (Bos taurus)

phospho-CHP1 [plasma membrane] (Gallus gallus)

phospho-CHP1 [plasma membrane] (Sus scrofa)

phospho-p-CHP1 [plasma membrane] (Canis familiaris)

phospho-Chp1 [plasma membrane] (Mus musculus)

phospho-Chp1 [plasma membrane] (Rattus norvegicus)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

RefSeq

NP_009167.1

ENSEMBL

ENST00000334660, ENSG00000187446, ENSP00000335632

OpenTargets

ENSG00000187446

GeneCards

CHP1

HPA

ENSG00000187446-CHP1

PRO

Q99653

Pharos - Targets

Q99653

GlyGen

Q99653

HMDB Protein

HMDBP02240

PDB

7DSV, 7DSX, 7X2U, 2E30

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q86UL3 GPAT4	1	AGPAT6 [endoplasmic reticulum membrane] (R-HSA-549099)	0.564	2
calcium(2+) [ChEBI:29108]	20	Ca2+ [endosome membrane] (R-ALL-5210949) Ca2+ [platelet dense granule lumen] (R-ALL-114582) Ca2+ [sarcoplasmic reticulum lumen] (R-ALL-2855229) Ca2+ [mitochondrial intermembrane space] (R-ALL-8949232) Ca2+ [lysosomal lumen] (R-ALL-1606834) Ca2+ [endocytic vesicle lumen] (R-ALL-8851519) Ca2+ [mitochondrial matrix] (R-ALL-8949220) Ca2+ [endoplasmic reticulum-Golgi intermediate compartment] (R-ALL-9706979) Ca2+ [Golgi lumen] (R-ALL-167012) Ca2+ [platelet dense tubular network lumen] (R-ALL-139827) Ca2+ [platelet dense tubular network membrane] (R-ALL-141090) Ca2+ [plasma membrane] (R-ALL-140648) Ca2+ [secretory granule lumen] (R-ALL-216801) Ca2+ [nuclear envelope] (R-ALL-2318767) Ca2+ [nucleoplasm] (R-ALL-29496) Ca2+ [mitochondrial inner membrane] (R-ALL-1524102) Ca2+ [endoplasmic reticulum membrane] (R-ALL-1500625) Ca2+ [cytosol] (R-ALL-74016) Ca2+ [extracellular region] (R-ALL-74112) Ca2+ [endoplasmic reticulum lumen] (R-ALL-111875)	0.558	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	4
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2

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