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phospho-Upf1 [cytosol]
Stable Identifier
R-RNO-927856
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
cytosol
Synonyms
p-4S-UPF1, A0A0U1RS25
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Rattus norvegicus)
Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Rattus norvegicus)
mRNA Cleaved by SMG6 [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
mRNA Cleaved by SMG6 [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
phospho-Upf1 [cytosol] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:A0A0U1RS25
Gene Names
Upf1
Reference Genes
ENSEMBL:ENSRNOG00000020134
UCSC:A0A0U1RS25 Upf1
Reference Transcript
RefSeq:XM_003751566.4 Upf1
RefSeq:XM_003752880.4 Upf1
Other Identifiers
10787579
17707182
5711228
5773204
5830403
6108355
6118629
6166025
6217815
6293505
6615073
684558
A_44_P1046976
A_64_P000549
A_64_P008672
GO:0000184
GO:0000781
GO:0000785
GO:0000956
GO:0003677
GO:0003682
GO:0003723
GO:0003724
GO:0003824
GO:0004386
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006260
GO:0006281
GO:0006449
GO:0008270
GO:0016071
GO:0016787
GO:0016887
GO:0032200
GO:0032201
GO:0032204
GO:0032508
GO:0035145
GO:0036121
GO:0042162
GO:0043226
GO:0044530
GO:0044770
GO:0044877
GO:0061014
GO:0061158
GO:0071044
GO:0140097
GO:0140098
GO:0140657
GO:1905746
PH_rn_0016737
Participates
as a component of
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
mRNA Cleaved by SMG6 [cytosol] (Rattus norvegicus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
This entity regulates
Positively
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex
(Rattus norvegicus)
Other forms of this molecule
Upf1 [cytosol]
Inferred From
p-4S-UPF1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1089 (in Homo sapiens)
Coordinate
1089
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1107 (in Homo sapiens)
Coordinate
1107
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1084 (in Homo sapiens)
Coordinate
1084
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1127 (in Homo sapiens)
Coordinate
1127
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ENSEMBL
ENSRNOP00000075905
,
ENSRNOT00000092446
RGD
1589127
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q01728
1
SLC8A1 [plasma membrane]
(R-RNO-425681)
0.462
2
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