Reactome | ALYREF [nucleoplasm]

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - RNA Polymerase II Transcription Termination (Homo sapiens)
    - Cleavage of mRNA at the 3'-end (Homo sapiens)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
        
        EJC [nucleoplasm] (Homo sapiens)
        
        ALYREF [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Homo sapiens)
        
        ALYREF [nucleoplasm] (Homo sapiens)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
        
        EJC [nucleoplasm] (Homo sapiens)
        
        ALYREF [nucleoplasm] (Homo sapiens)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Homo sapiens)
        
        ALYREF, FYTTD1, LUZP4 [nucleoplasm] (Homo sapiens)
        
        ALYREF [nucleoplasm] (Homo sapiens)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96FV9 THOC1	1	THOC1 [nucleoplasm] (R-HSA-8849130)	0.749	7
UniProt:Q13838 DDX39B	1	DDX39B [nucleoplasm] (R-HSA-8849139)	0.702	4
UniProt:Q9UBU9 NXF1	2	NXF1 [nucleoplasm] (R-HSA-111690) NXF1 [cytosol] (R-HSA-156481)	0.656	4
UniProt:Q8NI27 THOC2	1	THOC2 [nucleoplasm] (R-HSA-8849134)	0.643	4
UniProt:P31749 AKT1	13	p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308-AKT1 [cytosol] (R-HSA-198634) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356)	0.639	5
UniProt:Q13769 THOC5	1	THOC5 [nucleoplasm] (R-HSA-8849111)	0.623	5
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.597	3
UniProt:Q9Y3Y2 CHTOP	1	CHTOP [nucleoplasm] (R-HSA-8849147)	0.558	8
UniProt:Q6I9Y2 THOC7	1	THOC7 [nucleoplasm] (R-HSA-8849145)	0.527	2
UniProt:Q9H1J1 UPF3A	1	UPF3A [cytosol] (R-HSA-927801)	0.527	2
UniProt:P06493 CDK1	10	CDK1 [nucleoplasm] (R-HSA-68889) CDK1 [endoplasmic reticulum membrane] (R-HSA-264424) CDK1 [cytosol] (R-HSA-170075) p-T161-CDK1 [nucleoplasm] (R-HSA-170066) p-T161-CDK1 [cytosol] (R-HSA-157415) p-T14,Y15,T161-CDK1 [cytosol] (R-HSA-170071) p-T14,T161-CDK1 [nucleoplasm] (R-HSA-170078) p-T14,Y15,T161-CDK1 [nucleoplasm] (R-HSA-170074) p-T14-CDK1 [nucleoplasm] (R-HSA-170045) p-T14-CDK1 [cytosol] (R-HSA-170064)	0.499	4
UniProt:Q2HR75 ICP27			0.463	2