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phospho-p-4S-UPF1 [cytosol]
Stable Identifier
R-DME-927856
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q9VYS3
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Drosophila melanogaster)
Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
phospho-p-4S-UPF1 [cytosol] (Drosophila melanogaster)
SMG6 hydrolyzes mRNA with premature termination codon (Drosophila melanogaster)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
phospho-p-4S-UPF1 [cytosol] (Drosophila melanogaster)
mRNA Cleaved by SMG6 [cytosol] (Drosophila melanogaster)
phospho-p-4S-UPF1 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VYS3
Reference Genes
BioGPS Gene:32153
ENSEMBL:FBgn0030354
FlyBase:FBgn0030354
KEGG:dme:Dmel_CG1559
Monarch:32153
NCBI Gene:32153
UCSC:Q9VYS3
Reference Transcript
RefSeq:NM_132539.3
RefSeq:NM_001298216.1
Other Identifiers
144906_at
1623513_at
32153
GO:0000184
GO:0003677
GO:0003723
GO:0003724
GO:0003824
GO:0004386
GO:0005524
GO:0005737
GO:0008270
GO:0016071
GO:0016787
GO:0016887
GO:0032508
GO:0036121
GO:0036464
GO:0043226
GO:0046872
GO:0071456
GO:0071598
GO:0140097
GO:0140098
GO:0140657
GO:1990124
GO:2000624
Participates
as a component of
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Drosophila melanogaster)
mRNA Cleaved by SMG6 [cytosol] (Drosophila melanogaster)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Drosophila melanogaster)
Other forms of this molecule
UPF1 [cytosol]
HELZ2 [nucleoplasm]
Inferred From
p-4S-UPF1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1089 (in Homo sapiens)
Coordinate
1089
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1107 (in Homo sapiens)
Coordinate
1107
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1084 (in Homo sapiens)
Coordinate
1084
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1127 (in Homo sapiens)
Coordinate
1127
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_572767.1
,
NP_001285145.1
ENSEMBL
FBpp0073433
,
FBgn0030354
,
FBtr0342744
,
FBtr0073596
,
FBpp0309612
IntEnz
3.6.4.12
,
3.6.4.13
FlyBase
FBgn0030354
PRO
Q9VYS3
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O61307 TENM
0.462
2
UniProt:Q0KHS0 Q0KHS0
0.462
2
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