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phospho-upf1 [cytosol]
Stable Identifier
R-XTR-927856
Type
Protein [EntityWithAccessionedSequence]
Species
Xenopus tropicalis
Compartment
cytosol
Synonyms
p-4S-UPF1, A0A6I8T1P3
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Xenopus tropicalis)
Nonsense-Mediated Decay (NMD) (Xenopus tropicalis)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Xenopus tropicalis)
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex (Xenopus tropicalis)
mRNA Cleaved by SMG6 [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Xenopus tropicalis)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
SMG6 hydrolyzes mRNA with premature termination codon (Xenopus tropicalis)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
mRNA Cleaved by SMG6 [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Xenopus tropicalis)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
phospho-upf1 [cytosol] (Xenopus tropicalis)
External Reference Information
External Reference
UniProt:A0A6I8T1P3
Gene Names
upf1
Reference Genes
BioGPS Gene:100135270 upf1
ENSEMBL:ENSXETG00000013602
KEGG Gene (Xenopus tropicalis):100135270 upf1
Monarch:100135270 upf1
NCBI Gene:100135270 upf1
Reference Transcript
RefSeq:XM_002938826.5 upf1
Other Identifiers
100135270
GO:0000184
GO:0003677
GO:0003723
GO:0003724
GO:0003824
GO:0004386
GO:0005524
GO:0005737
GO:0008270
GO:0010468
GO:0016071
GO:0016787
GO:0046872
GO:0140098
GO:0140657
Participates
as a component of
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Xenopus tropicalis)
mRNA Cleaved by SMG6 [cytosol] (Xenopus tropicalis)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Xenopus tropicalis)
This entity regulates
Positively
Decay of mRNA in SMG6:SMG5:SMG7:mRNA complex
(Xenopus tropicalis)
Other forms of this molecule
upf1 [cytosol]
upf1 [nucleoplasm]
Inferred From
p-4S-UPF1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1089 (in Homo sapiens)
Coordinate
1089
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1107 (in Homo sapiens)
Coordinate
1107
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1084 (in Homo sapiens)
Coordinate
1084
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1127 (in Homo sapiens)
Coordinate
1127
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
XP_002938872.2
Xenbase
XB-GENE-6258022
Ensembl
ENSXETT00000069946
,
ENSXETP00000101161
,
ENSXETG00000013602
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