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CCNA1 [cytosol]
Stable Identifier
R-HSA-157446
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Cyclin A1
Icon
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)
Formation of Cyclin A:Cdc2 complexes (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
CCNA:CDK1 [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Myt-1 mediated phosphorylation of Cyclin A:Cdc2 (Homo sapiens)
CCNA:CDK1 [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
CCNA:p-T14-CDK1 [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Translocation of Cyclin A:phospho-Cdc2 (Thr 14) to the nucleus (Homo sapiens)
CCNA:p-T14-CDK1 [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)
Association of Cyclin A with the APC/C (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Degradation multiubiquitinated Cyclin A (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
Formation of Cyclin A:Cdk2 complexes (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
CCNA:CDK2 [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
Translocation of Cyclin A:Cdk2 complexes to the nucleus (Homo sapiens)
CCNA:CDK2 [cytosol] (Homo sapiens)
CCNA [cytosol] (Homo sapiens)
CCNA1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P78396 CCNA1
Gene Names
CCNA1
Chain
chain:1-465
Reference Genes
BioGPS Gene:8900 CCNA1
COSMIC (genes):CCNA1 CCNA1
CTD Gene:8900 CCNA1
dbSNP Gene:8900 CCNA1
ENSEMBL:ENSG00000133101 CCNA1
HGNC:1577 CCNA1
KEGG:hsa:8900 CCNA1
Monarch:8900 CCNA1
NCBI Gene:8900 CCNA1
OMIM:604036 CCNA1
UCSC:P78396 CCNA1
Reference Transcript
RefSeq:XM_011535296.2 CCNA1
RefSeq:NM_001111045.1 CCNA1
RefSeq:NM_003914.3 CCNA1
RefSeq:XM_011535295.2 CCNA1
RefSeq:NM_001111047.1 CCNA1
RefSeq:NM_001111046.1 CCNA1
RefSeq:XM_011535294.2 CCNA1
Other Identifiers
11732350_a_at
16774053
1914_at
205899_PM_at
205899_at
3485675
3485676
3485677
3485678
3485679
3485680
3485681
3485682
3485683
3485684
3485686
3485687
3485688
3485689
3485691
3485692
7968637
8900
A_14_P104510
A_23_P48414
GE80093
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0007141
GO:0007283
GO:0015630
GO:0016538
GO:0022414
GO:0043226
GO:0044772
GO:0051301
GO:0097121
GO:0097123
GO:0097124
GO:0098772
GO:0140013
HMNXSV003022709
ILMN_2157099
PH_hs_0019647
TC13000124.hg
U66838_at
g4502610_3p_at
Participates
as a candidate of
CCNA [cytosol] (Homo sapiens)
Other forms of this molecule
PolyUb-CCNA1 [nucleoplasm]
CCNA1 [nucleoplasm]
Inferred To
CCNA1 [cytosol]
(Bos taurus)
CCNA1 [cytosol]
(Caenorhabditis elegans)
CCNA1 [cytosol]
(Canis familiaris)
CCNA1 [cytosol]
(Gallus gallus)
CCNA1 [cytosol]
(Sus scrofa)
Ccna1 [cytosol]
(Mus musculus)
Ccna1 [cytosol]
(Rattus norvegicus)
CycA [cytosol]
(Drosophila melanogaster)
cya-1 [cytosol]
(Caenorhabditis elegans)
Homologues of CCNA1 [cytosol]
(Caenorhabditis elegans)
ccna1 [cytosol]
(Danio rerio)
ccna1 [cytosol]
(Xenopus tropicalis)
crs1 [cytosol]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_003905.1
,
XP_011533598.1
,
XP_011533597.1
,
NP_001104516.1
,
XP_011533596.1
,
NP_001104515.1
,
NP_001104517.1
ENSEMBL
ENST00000255465
,
ENSP00000486017
,
ENSP00000486482
,
ENST00000440264
,
ENST00000625767
,
ENSP00000400666
,
ENST00000630422
,
ENSP00000255465
OpenTargets
ENSG00000133101
HPA
ENSG00000133101-CCNA1
PRO
P78396
Pharos - Targets
P78396
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P38936 CDKN1A
5
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
CDKN1A [nucleoplasm]
(R-HSA-182585)
CDKN1A [cytosol]
(R-HSA-182512)
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
0.838
8
UniProt:P46527 CDKN1B
8
p-T187-CDKN1B [nucleoplasm]
(R-HSA-187525)
CDKN1B [nucleoplasm]
(R-HSA-182563)
p-Y88-CDKN1B [nucleoplasm]
(R-HSA-8942808)
p-Y88-CDKN1B [cytosol]
(R-HSA-8848438)
CDKN1B [cytosol]
(R-HSA-198622)
p-T157-CDKN1B [cytosol]
(R-HSA-198629)
p-S10 CDKN1B [nucleoplasm]
(R-HSA-9632832)
p-S10 CDKN1B [cytosol]
(R-HSA-9632829)
0.783
7
UniProt:Q05397 PTK2
11
p-6Y-PTK2 [cytosol]
(R-HSA-354128)
p-Y397-PTK2 [cytosol]
(R-HSA-354068)
PTK2 [cytosol]
(R-HSA-201621)
PTK2(1-772) [cytosol]
(R-HSA-202827)
PTK2(773-1052) [cytosol]
(R-HSA-202829)
p-5Y-PTK2 [cytosol]
(R-HSA-5218711)
p-5Y,S732-PTK2 [cytosol]
(R-HSA-5229006)
p-6Y,S732-PTK2 [cytosol]
(R-HSA-5218694)
pY-PTK2 [cytosol]
(R-HSA-9632393)
p-Y194,Y397-PTK2 [cytosol]
(R-HSA-8874600)
p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
(R-HSA-8874613)
0.536
2
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