Reactome | UQCRC1 [mitochondrial inner membrane]

UQCRC1 [mitochondrial inner membrane]

Stable Identifier

R-HSA-164284

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

Ubiquinol-cytochrome-c reductase complex core protein I, Complex III core protein I

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P31930 UQCRC1

Gene Names

UQCRC1

Chain

transit peptide:1-34, chain:35-480

Reference Genes

BioGPS Gene:7384 UQCRC1

COSMIC (genes):UQCRC1 UQCRC1

CTD Gene:7384 UQCRC1

dbSNP Gene:7384 UQCRC1

ENSEMBL:ENSG00000010256 UQCRC1

HGNC:12585 UQCRC1

KEGG Gene (Homo sapiens):7384 UQCRC1

Monarch:7384 UQCRC1

NCBI Gene:7384 UQCRC1

OMIM:191328 UQCRC1

UCSC:P31930 UQCRC1

Reference Transcript

RefSeq:NM_003365.2 UQCRC1

Other Identifiers

11743979_a_at

11747855_a_at

16953568

201903_at

2673510

2673511

2673512

2673516

2673517

2673518

2673519

2673521

2673522

2673524

2673526

2673527

2673529

2673530

2673533

2673534

283_at

7384

8087100

GE57651

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005743

GO:0005746

GO:0005750

GO:0006091

GO:0006119

GO:0006122

GO:0008121

GO:0008150

GO:0009060

GO:0014823

GO:0016020

GO:0016491

GO:0019899

GO:0031625

GO:0032991

GO:0043167

GO:0043226

GO:0043279

GO:0044877

GO:0046872

GO:0070469

L16842_at

PH_hs_0027224

TC03001384.hg

g4507840_3p_at

Participates

as a component of

Ubiquinol-cytochrome c reductase [mitochondrial inner membrane] (Homo sapiens)

Inferred To

qcr1 [mitochondrial inner membrane] (Schizosaccharomyces pombe)

MAS1 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

UQCR-C1 [mitochondrial inner membrane] (Drosophila melanogaster)

mppB [mitochondrial inner membrane] (Dictyostelium discoideum)

UQCRC1 [mitochondrial inner membrane] (Canis familiaris)

UQCRC1 [mitochondrial inner membrane] (Gallus gallus)

UQCRC1 [mitochondrial inner membrane] (Sus scrofa)

Uqcrc1 [mitochondrial inner membrane] (Mus musculus)

Uqcrc1 [mitochondrial inner membrane] (Rattus norvegicus)

uqcrc1 [mitochondrial inner membrane] (Danio rerio)

uqcrc1 [mitochondrial inner membrane] (Xenopus tropicalis)

COR1 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Homologues of UQCRC1 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_003356.2

OpenTargets

ENSG00000010256

HPA

ENSG00000010256-UQCRC1

GeneCards

P31930

Ensembl

ENST00000203407, ENSP00000203407, ENSG00000010256

PRO

P31930

Pharos - Targets

P31930

GlyGen

P31930

Orphanet

25021

HMDB Protein

HMDBP00987

PDB

5XTI, 5XTE, 5XTH

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P26641 EEF1G	3	EEF1G [cytosol] (R-HSA-156925) EEF1G(1-343)-p-6Y ALK(1106-1620) fusion [cytosol] (R-HSA-9710850) EEF1G(1-343)-ALK(1106-1620) fusion [cytosol] (R-HSA-9710839)	0.556	3
UniProt:Q00169 PITPNA	1	PITPNA [cytosol] (R-HSA-418391)	0.556	3
UniProt:Q06547-2 GABPB1	1	NRF2 beta-2 subunit [nucleoplasm] (R-HSA-1592200)	0.556	3
UniProt:O14744 PRMT5	3	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609)	0.556	3

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