Reactome | PFDN2 [cytosol]

PFDN2 [cytosol]

Stable Identifier

R-HSA-379544

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UHV9 PFDN2

Gene Names

PFDN2, PFD2, HSPC231

Chain

chain:1-154

Reference Genes

BioGPS Gene:5202 PFDN2

COSMIC (genes):PFDN2 PFDN2

CTD Gene:5202 PFDN2

dbSNP Gene:5202 PFDN2

ENSEMBL:ENSG00000143256 PFDN2

HGNC:8867 PFDN2

KEGG:hsa:5202 PFDN2

Monarch:5202 PFDN2

NCBI Gene:5202 PFDN2

OMIM:613466 PFDN2

UCSC:Q9UHV9 PFDN2

Reference Transcript

Other Identifiers

11716524_a_at

16695572

218336_PM_at

218336_at

2440609

2440611

2440613

2440614

2440616

2440617

2440620

2440621

48923_at

5202

57039_s_at

7921786

A_23_P51906

GE61143

GO:0001540

GO:0005515

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0006457

GO:0016272

GO:0043226

GO:0044183

GO:0050821

GO:0051082

GO:0051495

GO:0061077

GO:0101031

GO:1905907

GO:1990062

HMNXSV003046159

ILMN_1678754

PH_hs_0015402

TC01003416.hg

g12408674_3p_s_at

Participates

as a component of

Prefoldin [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSP00000356989, ENSG00000143256, ENST00000368010

OpenTargets

ENSG00000143256

GeneCards

PFDN2

HPA

ENSG00000143256-PFDN2

PRO

Q9UHV9

Pharos - Targets

Q9UHV9

GlyGen

Q9UHV9

PDB

6NRC, 6NRB, 7WU7, 6NRD, 6NR9, 6NR8

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.671	4
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.669	4
UniProt:Q13164 MAPK7	4	p-T218,Y221-MAPK7 [nucleoplasm] (R-HSA-198738) p-T218,Y221-MAPK7 [cytosol] (R-HSA-198721) MAPK7 [cytosol] (R-HSA-198754) MAPK7 [nucleoplasm] (R-HSA-199961)	0.643	4
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.643	3
UniProt:P63000 RAC1	6	RAC1 [plasma membrane] (R-HSA-351141) RAC1 [cytosol] (R-HSA-442615) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [secretory granule membrane] (R-HSA-6804770) RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802)	0.556	3
UniProt:P31930 UQCRC1	1	UQCRC1 [mitochondrial inner membrane] (R-HSA-164284)	0.556	3
UniProt:Q7KZ85 SUPT6H	1	SUPT6H [nucleoplasm] (R-HSA-8932908)	0.527	2
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.527	2
UniProt:Q92466 DDB2	3	DDB2 [nucleoplasm] (R-HSA-53491) PAR-DDB2 [nucleoplasm] (R-HSA-5696654) PolyUb-DDB2 [nucleoplasm] (R-HSA-6783035)	0.527	3
UniProt:O60508 CDC40	1	CDC40 [nucleoplasm] (R-HSA-72062)	0.527	2
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.527	2
UniProt:Q8IXW5 RPAP2	1	RPAP2 [nucleoplasm] (R-HSA-6810227)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	8

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