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ARHGDIB [cytosol]
Stable Identifier
R-HSA-195081
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rho GDIbeta/GDI2
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GDIs block activation of CDC42 (Homo sapiens)
CDC42 GDIs [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
CDC42:GDP:CDC42 GDIs [cytosol] (Homo sapiens)
CDC42 GDIs [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GDIs block activation of RAC1 (Homo sapiens)
ARHGDIA,ARHGDIB [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RAC1:GDP:RAC1 GDIs [cytosol] (Homo sapiens)
ARHGDIA,ARHGDIB [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GDIs block activation of RAC3 (Homo sapiens)
RAC3 GDIs [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RAC3:GDP:RAC3 GDIs [cytosol] (Homo sapiens)
RAC3 GDIs [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
GDIs block activation of RHOA (Homo sapiens)
ARHGDIA,ARHGDIB [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RHOA GDIs:RHOA:GDP [cytosol] (Homo sapiens)
ARHGDIA,ARHGDIB [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RHOG GTPase cycle (Homo sapiens)
GDIs block activation of RHOG (Homo sapiens)
ARHGDIA,ARHGDIB,ARHGDIG [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RHOG GDIs:RHOG:GDP [cytosol] (Homo sapiens)
ARHGDIA,ARHGDIB,ARHGDIG [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RHOH GTPase cycle (Homo sapiens)
GDIs bind RHOH (Homo sapiens)
ARHGDIA,ARHGDIB,ARHGDIG [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
RHOH:GTP:RHOH GDIs [cytosol] (Homo sapiens)
ARHGDIA,ARHGDIB,ARHGDIG [cytosol] (Homo sapiens)
ARHGDIB [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P52566 ARHGDIB
Gene Names
ARHGDIB, GDIA2, GDID4, RAP1GN1
Chain
initiator methionine:1, chain:2-201
Reference Genes
BioGPS Gene:397 ARHGDIB
COSMIC (genes):ARHGDIB ARHGDIB
CTD Gene:397 ARHGDIB
dbSNP Gene:397 ARHGDIB
ENSEMBL:ENSG00000111348 ARHGDIB
HGNC:679 ARHGDIB
KEGG Gene (Homo sapiens):397 ARHGDIB
Monarch:397 ARHGDIB
NCBI Gene:397 ARHGDIB
OMIM:602843 ARHGDIB
UCSC:P52566 ARHGDIB
Reference Transcript
RefSeq:NM_001321421.1 ARHGDIB
RefSeq:NM_001321423.1 ARHGDIB
RefSeq:NM_001321420.1 ARHGDIB
RefSeq:NM_001175.6 ARHGDIB
RefSeq:NM_001321422.1 ARHGDIB
Other Identifiers
0004150156
11715466_at
11715467_s_at
1555812_a_at
16761843
1984_s_at
201288_at
3445787
3445788
3445789
3445790
3445791
3445796
3445799
3445801
3445802
3445803
3445804
3445807
397
7961532
A_23_P151075
GE57665
GE86119
GO:0000003
GO:0003674
GO:0003924
GO:0005094
GO:0005096
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005829
GO:0005856
GO:0007010
GO:0007155
GO:0007162
GO:0007165
GO:0007266
GO:0007275
GO:0008150
GO:0016020
GO:0019899
GO:0030234
GO:0031267
GO:0031410
GO:0035023
GO:0040011
GO:0043226
GO:0043547
GO:0048856
GO:0048870
GO:0050790
GO:0051056
GO:0070062
GO:0071461
GO:1901164
GO:2000249
HMNXSV003008142
ILMN_1678143
L20688_at
TC12001278.hg
X89399_s_at
g10835001_3p_at
Participates
as a member of
CDC42 GDIs [cytosol] (Homo sapiens)
ARHGDIA,ARHGDIB [cytosol] (Homo sapiens)
ARHGDIA,ARHGDIB,ARHGDIG [cytosol] (Homo sapiens)
as a candidate of
RAC3 GDIs [cytosol] (Homo sapiens)
Inferred To
RDI1 [cytosol]
(Saccharomyces cerevisiae)
arhgdig [cytosol]
(Danio rerio)
rhi-1 [cytosol]
(Caenorhabditis elegans)
RhoGDI [cytosol]
(Drosophila melanogaster)
ARHGDIB [cytosol]
(Bos taurus)
ARHGDIB [cytosol]
(Canis familiaris)
ARHGDIB [cytosol]
(Gallus gallus)
ARHGDIB [cytosol]
(Schizosaccharomyces pombe)
ARHGDIB [cytosol]
(Sus scrofa)
Arhgdib [cytosol]
(Mus musculus)
Arhgdib [cytosol]
(Rattus norvegicus)
rdiA [cytosol]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001308352.1
,
NP_001308349.1
,
NP_001308351.1
,
NP_001166.3
,
NP_001308350.1
OpenTargets
ENSG00000111348
GeneCards
P52566
HPA
ENSG00000111348-ARHGDIB
Ensembl
ENSP00000444860
,
ENST00000228945
,
ENSP00000440560
,
ENST00000541546
,
ENSG00000111348
,
ENSP00000228945
,
ENST00000541644
PRO
P52566
Pharos - Targets
P52566
GlyGen
P52566
HMDB Protein
HMDBP01787
PDB
5H1D
,
1DS6
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.556
3
UniProt:P01100 FOS
2
FOS [nucleoplasm]
(R-HSA-450216)
p-T325,T331,S362,S374-FOS [nucleoplasm]
(R-HSA-450283)
0.556
3
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